Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Mary Cherian-Shaw"'
Autor:
Evgenia Gerasimovskaya, Rahul S. Patil, Adrian Davies, McKenzie E. Maloney, Liselle Simon, Basmah Mohamed, Mary Cherian-Shaw, Alexander D. Verin
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
The purinergic signaling system is an evolutionarily conserved and critical regulatory circuit that maintains homeostatic balance across various organ systems and cell types by providing compensatory responses to diverse pathologies. Despite cardiova
Externí odkaz:
https://doaj.org/article/42e1427200574c2595c2de227c691497
Autor:
Pushpankur Ghoshal, Bhupesh Singla, Huiping Lin, Mary Cherian-Shaw, Rebekah Tritz, Caleb A. Padgett, Farlyn Hudson, Hanfang Zhang, Brian K. Stansfield, Gábor Csányi
Publikováno v:
Redox Biology, Vol 27, Iss , Pp - (2019)
Neurofibromin, the protein product of the neurofibromatosis type 1 (NF1) tumor suppressor gene, is a negative regulator of Ras signaling. Patients with mutations in NF1 have a strong predisposition for cardiovascular disease, which contributes to the
Externí odkaz:
https://doaj.org/article/c6b788497f584fccae6f02f8da35ba5a
Autor:
Christine M Gross, Ruslan Rafikov, Sanjiv Kumar, Saurabh Aggarwal, P Benson Ham, Mary Louise Meadows, Mary Cherian-Shaw, Archana Kangath, Supriya Sridhar, Rudolf Lucas, Stephen M Black
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0119918 (2015)
Lipopolysaccharide (LPS) derived from the outer membrane of gram-negative bacteria induces acute lung injury (ALI) in mice. This injury is associated with lung edema, inflammation, diffuse alveolar damage, and severe respiratory insufficiency. We hav
Externí odkaz:
https://doaj.org/article/f2c4dc4e9346442ab7e622bd3ea70116
Autor:
John Henry Dasinger, Samuel D. Walton, Emily C. Burns, Mary Cherian-Shaw, Justine M. Abais-Battad, David L. Mattson
Publikováno v:
American journal of physiology. Renal physiology. 323(6)
Salt-sensitive hypertension, increases in blood pressure in response to increased salt intake, is associated with an increased risk of morbidity, mortality, and end-organ damage compared with salt-resistant hypertension. The Dahl salt-sensitive (SS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55a4ade1837bd867a4d2b910940a1a17
https://pubmed.ncbi.nlm.nih.gov/36108053
https://pubmed.ncbi.nlm.nih.gov/36108053
Autor:
John Henry Dasinger, Justine Abais-Battad, Mary Cherian-Shaw, Emily Burns, Samuel Walton, David Mattson
Publikováno v:
Physiology. 38
Preeclampsia (PE) is a pregnancy-specific disorder that is characterized by hypertension and proteinuria (maternal syndrome). Our group has demonstrated that Dahl salt-sensitive rats maintained on a low salt casein-based diet (SSC) develop maternal s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29dccbb1f68d013713fd014c24e47662
https://doi.org/10.1152/physiol.2023.38.s1.5733410
https://doi.org/10.1152/physiol.2023.38.s1.5733410
Autor:
Emily Burns, John Dasinger, Mary Cherian-Shaw, Samuel Walton, Justine Abais-Battad, David Mattson
Publikováno v:
Physiology. 38
Renal inflammation accompanies hypertension and renal damage in Dahl Salt-Sensitive rats fed a high salt diet (HS, 4.0% NaCl). Via a transcriptomics approach, we previously found cluster of differentiation 14 (CD14) and toll-like receptor 4 (TLR4), p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c7892b4bd69bad6e7515321cc379670
https://doi.org/10.1152/physiol.2023.38.s1.5734225
https://doi.org/10.1152/physiol.2023.38.s1.5734225
Autor:
Hannah Godley, John Henry Dasinger, Mary Cherian-Shaw, Aleksandra Zamaro, Denisha Spires, Daria Ilatovskaya, David Mattson, Justine Abias-Battad, Jennifer Sullivan
Publikováno v:
Physiology. 38
There are numerous reports that male Dahl rats have greater increases in BP with a high-salt (HS) diet than females, yet women have been suggested to be more salt-sensitive than men. Since the typical Western diet consists of both HS and high-fat (HF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a91ea18d5143da002a07d2061e103391
https://doi.org/10.1152/physiol.2023.38.s1.5733195
https://doi.org/10.1152/physiol.2023.38.s1.5733195
Autor:
Samuel Walton, John Henry Dasinger, Mary Cherian-Shaw, Emily Burns, Justine Abais-Battad, David Mattson
Publikováno v:
Physiology. 38
Infiltration of T cells into the kidney of the Dahl Salt Sensitive (SS), a rat model of human disease, accompanies the development of salt-sensitive hypertension and renal damage. Deletion of T cells on the Dahl SS genetic background (SSCD247-/-) att
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::838bebae59def96f9f55cc45509dfdea
https://doi.org/10.1152/physiol.2023.38.s1.5733783
https://doi.org/10.1152/physiol.2023.38.s1.5733783
Autor:
Bhupesh Singla, Hui-Ping Lin, WonMo Ahn, Jiean Xu, Qian Ma, Moses Sghayyer, Kunzhe Dong, Mary Cherian-Shaw, Jiliang Zhou, Yuqing Huo, Joseph White, Gábor Csányi
Publikováno v:
Cardiovasc Res
AimsInhibitors of the anti-phagocytic CD47-SIRPα immune checkpoint are currently in clinical development for a variety of haematological and solid tumours. Application of immune checkpoint inhibitors to the cardiovascular field is limited by the lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::081846986d462303861eb777f74b3381
https://doi.org/10.1093/cvr/cvab369
https://doi.org/10.1093/cvr/cvab369
Autor:
David L. Mattson, Rebekah L. Gundry, John Henry Dasinger, Theodore Keppel, Hayley Lund, Jeylan Zemaj, Daniel J. Fehrenbach, Mary Cherian-Shaw, Justine M. Abais-Battad, Melinda R. Dwinell, Aron M. Geurts
Publikováno v:
Hypertension. 77:228-240
Genomic sequence and gene expression association studies in animals and humans have identified genes that may be integral in the pathogenesis of various diseases. CD14 (cluster of differentiation 14)—a cell surface protein involved in innate immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae11cd7f8bfc652c9d8e4967bb3d91e5
https://doi.org/10.1161/hypertensionaha.120.14928
https://doi.org/10.1161/hypertensionaha.120.14928