Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Mary C. Gannon"'
Publikováno v:
Physiological Reports, Vol 8, Iss 19, Pp n/a-n/a (2020)
Abstract Objective We have been interested in determining the effects of dietary changes on fuel metabolism and regulation in men with type 2 diabetes mellitus (T2DM). In this study, the changes in 24‐hr circulating lipid profiles were determined w
Externí odkaz:
https://doaj.org/article/a104266f49624e7b958bf13d90c2d064
Publikováno v:
Journal of Diabetes Science and Technology. 16:1532-1540
Background: Current mathematical models of postprandial glucose metabolism in people with normal and impaired glucose tolerance rely on insulin measurements and are therefore not applicable in clinical practice. This research aims to develop a model
Autor:
Mary C. Gannon, Talene A. Yacoubian
Publikováno v:
Trends Pharmacol Sci
14-3-3 proteins enact a wide range of cellular functions through protein-protein interactions with client proteins. Kaplan and colleagues [1] recently demonstrated that a semi-synthetic compound was able to selectively stabilize or disrupt specific i
Autor:
Alyssa Klop, Rachel Underwood, Navya Kapa, Talene A. Yacoubian, Sidhanth Chandra, Mary C. Gannon, Aneesh Pathak
Publikováno v:
Acta Neuropathologica Communications, Vol 9, Iss 1, Pp 1-16 (2021)
Acta Neuropathologica Communications
Acta Neuropathologica Communications
Alpha-synuclein (αsyn) is the key component of proteinaceous aggregates termed Lewy Bodies (LBs) that pathologically define a group of disorders known as synucleinopathies, including Parkinson’s Disease (PD) and Dementia with Lewy Bodies (DLB). α
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103b209666496658d2107c2c6082caf8
https://doi.org/10.1101/2020.11.17.387415
https://doi.org/10.1101/2020.11.17.387415
Publikováno v:
Physiological Reports
Physiological Reports, Vol 8, Iss 19, Pp n/a-n/a (2020)
Physiological Reports, Vol 8, Iss 19, Pp n/a-n/a (2020)
Objective We have been interested in determining the effects of dietary changes on fuel metabolism and regulation in men with type 2 diabetes mellitus (T2DM). In this study, the changes in 24‐hr circulating lipid profiles were determined when the m
Publikováno v:
Computer methods and programs in biomedicine. 200
Background and objective\ud The oral minimal model (OMM) of glucose dynamics is a prominent method for assessing postprandial glucose metabolism. The model yields estimates of insulin sensitivity and the meal-related appearance of glucose from insuli
Autor:
Bingdong Sha, Zhenghui Liu, Mary C. Gannon, Shun Yan, Jiahui Tao, Qin Wang, Takaomi C. Saido, Takashi Saito, Fang Zhang, C. Dirk Keene, Yunjia Chen, Sixue Zhang, Wendy Feng, Kai Jiao, Erik D. Roberson, Huaxi Xu
Publikováno v:
Sci Transl Med
The brain noradrenergic system is critical for normal cognition and is affected at early stages in Alzheimer's disease (AD). Here, we reveal a previously unappreciated direct role of norepinephrine signaling in connecting β-amyloid (Aβ) and tau, tw
Publikováno v:
European Journal of Clinical Pharmacology
Purpose A large number of medications have been implicated in the genesis of gynecomastia. However, gynecomastia is common in men, asymptomatic, increases with age, and is considered to be due to an increased estradiol/testosterone ratio. This compli
Publikováno v:
Metabolism. 64:253-262
Objective Hyperglycemia improves when patients with type 2 diabetes are placed on a weight-loss diet. Improvement typically occurs soon after diet implementation. This rapid response could result from low fuel supply (calories), lower carbohydrate co
The amyloid precursor protein (APP) has long been appreciated for its role in Alzheimer's disease (AD) pathology. However, less is known about the physiologic function of APP outside of AD. Particularly, whether and how APP may regulate functions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df5c5048f74bc7b018f61961dfdd05bf
https://europepmc.org/articles/PMC5602903/
https://europepmc.org/articles/PMC5602903/