Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mary Bushman"'
Publikováno v:
PLoS Biology, Vol 16, Iss 8, p e2005712 (2018)
In the malaria parasite P. falciparum, drug resistance generally evolves first in low-transmission settings, such as Southeast Asia and South America. Resistance takes noticeably longer to appear in the high-transmission settings of sub-Saharan Afric
Externí odkaz:
https://doaj.org/article/c34f9a2dd305494eb4acae3d079111b3
Publikováno v:
PLoS Genetics, Vol 9, Iss 3, p e1003312 (2013)
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR), together with associated genes (cas), form the CRISPR-cas adaptive immune system, which can provide resistance to viruses and plasmids in bacteria and archaea. Here, we use mathemati
Externí odkaz:
https://doaj.org/article/c29d0fe055684e7c930721cbbc87d2e8
Publikováno v:
Cell Host & Microbe. 29:1048-1051
If enough individuals in a population are immune to a pathogen, it cannot cause an outbreak. Deliberately seeking such herd immunity through infection during a potentially lethal pandemic is contrary to all principles of public health, given the pote
Publikováno v:
European Journal of Epidemiology
Nonpharmaceutical interventions, such as contact tracing and quarantine, have been the primary means of controlling the spread of SARS-CoV-2; however, it remains uncertain which interventions are most effective at reducing transmission at the populat
Autor:
Marc Lipsitch, Benjamin J. Cowling, Gabriel M. Leung, Kathy Leung, Joseph T. Wu, Rene Niehus, Mary Bushman, Nishant Kishore, Pablo Martinez de Salazar
Publikováno v:
Nature Medicine
As of 29 February 2020 there were 79,394 confirmed cases and 2,838 deaths from COVID-19 in mainland China. Of these, 48,557 cases and 2,169 deaths occurred in the epicenter, Wuhan. A key public health priority during the emergence of a novel pathogen
Autor:
Nina Wale, Pamela J. Yeh, Robin N Thompson, Farrah Bashey, Christina L. Faust, Ana I. Bento, Philipp Schwabl, Troy Day, Mary Bushman, Caroline K. Glidden, David R. Daversa, Sylvain Gandon, Lauren M. Childs, Andrew F. Read, Helen J. Wearing, Amy R. Sweeny, Fletcher W. Halliday, Ann T. Tate, Molly E. Gallagher, Megan A. Greischar, Amrita Bhattacharya, Kathryn A. Hanley, Nicole Mideo, Helen K. Alexander, Tsukushi Kamiya
Publikováno v:
Evolution, Medicine, and Public Health
Evolution, medicine, and public health
Alexander, H K, Bashey, F, Bento, A I, Bhattacharya, A, Bushman, M, Childs, L M, Daversa, D R, Day, T, Faust, C L, Gallagher, M E, Gandon, S, Glidden, C K, Halliday, F W, Hanley, K A, Kamiya, T, Read, A F, Schwabl, P, Sweeny, A R, Tate, A T, Thompson, R N, Wale, N, Wearing, H J, Yeh, P J, Mideo, N & Greischar, M A 2020, ' Evolutionary consequences of feedbacks between within-host competition and disease control ', Evolution, Medicine and Public Health, vol. 2020, no. 1, pp. 30-34 . https://doi.org/10.1093/emph/eoaa004
Evolution, medicine, and public health
Alexander, H K, Bashey, F, Bento, A I, Bhattacharya, A, Bushman, M, Childs, L M, Daversa, D R, Day, T, Faust, C L, Gallagher, M E, Gandon, S, Glidden, C K, Halliday, F W, Hanley, K A, Kamiya, T, Read, A F, Schwabl, P, Sweeny, A R, Tate, A T, Thompson, R N, Wale, N, Wearing, H J, Yeh, P J, Mideo, N & Greischar, M A 2020, ' Evolutionary consequences of feedbacks between within-host competition and disease control ', Evolution, Medicine and Public Health, vol. 2020, no. 1, pp. 30-34 . https://doi.org/10.1093/emph/eoaa004
Lay Summary: Competition often occurs among diverse parasites within a single host, but control efforts could change its strength. We examined how the interplay between competition and control could shape the evolution of parasite traits like drug re
Population impact of SARS-CoV-2 variants with enhanced transmissibility and/or partial immune escape
Publikováno v:
Cell
SARS-CoV-2 variants of concern exhibit varying degrees of transmissibility and, in some cases, escape from acquired immunity. Much effort has been devoted to measuring these phenotypes, but understanding their impact on the course of the pandemic –
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edd34980a95d8225c9ab58270443746b
https://doi.org/10.1101/2021.08.26.21262579
https://doi.org/10.1101/2021.08.26.21262579
Autor:
Newsha Ghaeli, Mariana Matus, Xiaoqiong Gu, Steven F Rhode, Eric J. Alm, Fuqing Wu, Janelle R. Thompson, Amy Xiao, Katya Moniz, Mary Bushman, William P. Hanage, Katherine H. Huang, Kyle A. McElroy, Katelyn Foppe, Noriko Endo, Wei Lin Lee, Claire Duvallet, Stefan Wuertz, Jianbo Zhang, Peter R. Chai, Timothy B. Erickson, Federica Armas
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 2
article-version (status) pre
article-version (number) 2
Wastewater-based disease surveillance is a promising approach for monitoring community outbreaks. Here we describe a nationwide campaign to monitor SARS-CoV-2 in the wastewater of 159 counties in 40 U.S. states, covering 13% of the U.S. population fr
Autor:
William P. Hanage, Steven F Rhode, Timothy B. Erickson, Katya Moniz, Xiaoqiong Gu, Kyle A. McElroy, Federica Armas, Janelle R. Thompson, Claire Duvallet, Jianbo Zhang, Amy Xiao, Maxim Imakaev, Eric J. Alm, Mariana Matus, Hongjie Chen, Peter R. Chai, Wei Lin Lee, Brian J. Arnold, Franciscus Chandra, Newsha Ghaeli, Fuqing Wu, Mary Bushman, Noriko Endo
Publikováno v:
medRxiv
article-version (status) pre
article-version (number) 1
Water Research
article-version (status) pre
article-version (number) 1
Water Research
Wastewater surveillance has emerged as a useful tool in the public health response to the COVID-19 pandemic. While wastewater surveillance has been applied at various scales to monitor population-level COVID-19 dynamics, there is a need for quantitat
Autor:
Newsha Ghaeli, Megan A. Brown, Mariana Matus, Claire Duvallet, Janelle R. Thompson, Stefan Wuertz, Jianbo Zhang, Federica Armas, Fuqing Wu, Richard Bonneau, Amy Xiao, Kyle A. McElroy, William P. Hanage, Mauricio Santillana, Steven F Rhode, Joshua A. Tucker, Katelyn Foppe, Jonathan Nagler, Xiaoqiong Gu, Katherine H. Huang, Eric J. Alm, Mary Bushman, Katya Moniz, Noriko Endo, Shijie Zhao, Wei Lin Lee, Peter R. Chai, Timothy B. Erickson
Publikováno v:
mSystems
medRxiv
article-version (status) pre
article-version (number) 1
medRxiv
article-version (status) pre
article-version (number) 1
Wastewater-based surveillance is a promising approach for proactive outbreak monitoring. SARS-CoV-2 is shed in stool early in the clinical course and infects a large asymptomatic population, making it an ideal target for wastewater-based monitoring.