Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Mary Brinkoetter"'
Autor:
Huizhi Gong, Xiaowen Liu, Joo Young Huh, O-P R Hamnvik, Christos S. Mantzoros, John P. Chamberland, Mary Brinkoetter
Publikováno v:
International Journal of Obesity. 39:1548-1557
Obesity is characterized by chronic inflammation and immune dysregulation, as well as insulin resistance, but the link between obesity and adaptive immunity remains to be fully studied. To elucidate the role of adaptive immunity on body composition,
Autor:
Bang-Bon Koo, Rafael Rojas, Mary Brinkoetter, Panagiotis Papageorgiou, Christos S. Mantzoros, Florencia Ziemke, Olivia M. Farr, Christina G. Fiorenza
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 99:E2529-E2538
Context: Leptin is a key regulator of energy intake and expenditure. Individuals with congenital leptin deficiency demonstrate structural and functional brain changes when given leptin. However, whether acquired leptin deficiency may operate similarl
Autor:
Cindy Crowell-Doom, Kyung Hee Park, Nicole Usher, Kyoung Eun Joung, Eric Dearing, Christos S. Mantzoros, Judith A. Crowell, Elizabeth Ollen, Sarah Trifiletti, Mary Brinkoetter, Cynthia Davis, Lesya Zaichenko
Publikováno v:
Metabolism. 63:199-206
Objective This study examined whether a novel indicator of overall childhood adversity, incorporating number of adversities, severity, and chronicity, predicted central obesity beyond contributions of “modifiable” risk factors including psychosoc
Autor:
Christos S. Mantzoros, Ole-Petter R. Hamnvik, Lesya Zaichenko, Mary Brinkoetter, John P. Chamberland, Joo-Pin Foo, Bindiya Thakkar, Konstantinos N. Aronis
Publikováno v:
Obesity. 21:E527-E532
Objective Undercarboxylated osteocalcin (ucOC) is a bone marker with potent metabolic effects. Leptin regulates Esp gene expression and osteocalcin carboxylation in animal models. We aim to elucidate day/night patterns of ucOC levels, whether short-t
Autor:
Huizhi Gong, Nikolaos Perakakis, Xiaowen Liu, Ole-Petter R. Hamnvik, John P. Chamberland, Christos S. Mantzoros, Mary Brinkoetter
Publikováno v:
Metabolism: clinical and experimental. 65(12)
Obesity is associated with chronic low-grade inflammation leading to insulin resistance and diabetes. Adiponectin is an adipokine that regulates inflammatory responses. The aim of our study was to investigate whether any effects of adiponectin agains
Publikováno v:
Yonsei Medical Journal
Leptin, a peptide hormone secreted by adipocytes in proportion of the amount of energy stored in fat, plays a central role in regulating human energy homeostasis. In addition, leptin plays a significant permissive role in the physiological regulation
Autor:
Xiaowen Liu, Jutta M. Nagel, Jin-Rong Zhou, George L. Blackburn, Christos S. Mantzoros, Mary Brinkoetter, Sunali Shah, Faidon Magkos, John P. Chamberland
Publikováno v:
Nutrition. 28:67-75
Animal studies have demonstrated that dietary supplementation with flaxseed oil inhibits colorectal cancer growth. Recent data indicate that walnuts have strong antiproliferative properties against colon cancer cells in vitro but no previous study ha
Autor:
Sharon H. Chou, Anastasia Koniaris, Elizabeth Sienkiewicz, Faidon Magkos, Konstantinos N. Aronis, Kalliopi M. Arampatzi, Mary Brinkoetter, Chuanyun Gao, John P. Chamberland, Christos S. Mantzoros
Publikováno v:
Metabolism. 60:1211-1221
Strenuously exercising young women with hypothalamic amenorrhea are hypoleptinemic and have low bone mineral density (BMD) and content (BMC), which predispose them to increased fracture risk. Short-term leptin replacement in these women corrects many
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 301:E99-E104
Animal studies in vivo indicate that leptin treatment in extremely leptin-sensitive ob/ ob mice reduces body weight exclusively by reducing fat mass and that it increases muscle mass by downregulating myostatin expression. Data from human trials are
Autor:
Ivana Nikić, Thomas Misgeld, Stephanie Potz, Mary Brinkoetter, Martin Kerschensteiner, Sharmon M. Knecht, Derron L. Bishop
Publikováno v:
Nature Methods. 8:568-570
The correlation of light and electron microscopy of complex tissues remains a major challenge. Here we report near-infrared branding (NIRB), which facilitates such correlation by using a pulsed, near-infrared laser to create defined fiducial marks in