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Effect of an Insulin-Like Growth Factor Binding Protein Fusion Protein on Thymidine Incorporation in Neuroblastoma and Rhabdomyosarcoma Cell Lines

Autor: Brian L. Dake, Leon A. Bach, Mary Boes, Robert S. Bar

Publikováno v: Endocrinology. 145:3369-3374

A fusion protein, FP 6/3, composed of IGF binding protein (IGFBP)-6 and IGFBP-3 was synthesized where the complete sequences of each binding protein were fused together into a single chimeric protein. The orientation of this fusion protein's structur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaa00fd3a935f3160eaf5cee2aafd413
https://doi.org/10.1210/en.2003-1667

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Structure–function relationships of insulin-like growth factor binding protein 6 (IGFBP-6) and its chimeras

Autor: Alexander Sandra, M Bateman, Brian L. Dake, Robert S. Bar, Mary Boes, Kevin L. Knudtson, Barbara A. Booth

Publikováno v: Growth Hormone & IGF Research. 12:91-98

Insulin-like growth factor binding protein 6 (IGFBP-6) is a high-affinity IGFBP with substantially greater affinity for insulin-like growth factor-II (IGF-II) than IGF-I. IGFBP-6(3) is a chimera which has a 20 amino acidC -terminal portion of IGFBP-6

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66e5041f98e4941576cfda38f6d6811d
https://doi.org/10.1054/ghir.2001.0266

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Distribution of Chimeric IGF Binding Protein (IGFBP)-3 and IGFBP-4 in the Rat Heart: Importance of C-Terminal Basic Region

Autor: Kevin L. Knudtson, Brian L. Dake, Robert S. Bar, Alexander Sandra, Mary Boes, Barbara A. Booth

Publikováno v: Endocrinology. 142:3749-3755

IGF binding proteins-3 and -4, whether given in the perfused rat heart or given iv in the intact animal, cross the microvascular endothelium of the heart and distribute in subendothelial tissues. IGF binding protein-3, like IGF-I/II, localizes in car

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc1596b6ba81287769330c1e8ec3a15
https://doi.org/10.1210/endo.142.9.8353

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Isolation and characterization of plasmin-generated bioactive fragments of IGFBP-3

Autor: Barbara A. Booth, Robert S. Bar, Brian L. Dake, Mary Boes

Publikováno v: American Journal of Physiology-Endocrinology and Metabolism. 276:E450-E454

Insulin-like growth factor-binding protein-3 (IGFBP-3) was digested with plasmin, and the proteolytic fragments were isolated by HPLC and tested for bioactivity as measured by stimulation of glucose uptake in microvessel endothelial cells. Two of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08106f0ec512d7656386433ccdc658e8
https://doi.org/10.1152/ajpendo.1999.276.3.e450

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Transcriptional and Posttranscriptional Regulation of Insulin-Like Growth Factor Binding Protein-3 by Cyclic Adenosine 3′,5′-Monophosphate: Messenger RNA Stabilization Is Accompanied by Decreased Binding of a 42-kDa Protein to a Uridine-Rich Domain in the 3′-Untranslated Region

Autor: J. Nwankwo, Robert S. Bar, Mary Boes, Y. Zhong, Ngozi E. Erondu, Brian L. Dake

Publikováno v: Molecular Endocrinology. 13:495-504

The Madin Darby bovine kidney (MDBK) cell line was used to investigate the mechanisms underlying the cAMP regulation of insulin-like growth factor binding protein-3 (IGFBP-3) gene expression. Treatment of confluent monolayers either with forskolin or

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::814fbef45b73be8d8456d4c7c01fa40f
https://doi.org/10.1210/mend.13.3.0252

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Social Work With Homeless Women in Emergency Rooms: A Strengths-Feminist Perspective

Autor: Mary Boes, Katherine van Wormer

Publikováno v: Affilia. 12:408-426

This article presents a combined strengths-feminist framework for work with homeless women. The framework focuses on the survival skills of homeless women (many of whom are mothers and victims of wife abuse)-resources that emergency room social worke

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb8eed1568bcd7873839c80dd1e2da11
https://doi.org/10.1177/088610999701200404

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Bovine Insulin-Like Growth Factor Binding Protein-3: Organization of the Chromosomal Gene and Functional Analysis of Its Promoter

Autor: Ngozi E. Erondu, B. Toland, Robert S. Bar, Brian L. Dake, David R. Moser, Mary Boes

Publikováno v: Endocrinology. 138:2856-2862

Insulin-like growth factor binding protein-3 (IGFBP-3), the major IGFBP in the circulation, is synthesized by the vascular endothelium in vivo and has been shown to be an important modulator of the physiological effects of IGF. IGFBP-3 is regulated b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494989dc10adcb291d0a1d727c5c1eff
https://doi.org/10.1210/endo.138.7.5288

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Humor in the Emergency Room: A Social Work Perspective

Autor: Katherine van Wormer, Mary Boes

Publikováno v: Health & Social Work. 22:87-92

Social workers can learn much about the uses of humor from workers in the turbulent and fast-paced atmosphere of a large city hospital emergency room in which it flourishes. This article illustrates staff use of five varieties of humor in this stress

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0d87d505a8cbe4c6c7a2f735cf6870d
https://doi.org/10.1093/hsw/22.2.87

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