Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mary Beth Bowen-Yacyshyn"'
Publikováno v:
Digestive Diseases and Sciences. 41:2493-2498
Increased intestinal permeability and the CD45RO isoform expression of the leukocyte common antigen on peripheral blood CD20+ B cells are found in Crohn's disease. Others have observed that multiple sclerosis (MS) patients may have an increased risk
Publikováno v:
Scandinavian Journal of Immunology. 43:449-455
P-glycoprotein 170 encoded by the MDR-1 gene mediates export of substrates including some immunosuppressive drugs. Rapamycin was compared to cyclosporine A for its ability to inhibit P-glycoprotein on normal human peripheral blood mononuclear cells (
Publikováno v:
Human immunology. 60(8)
The clinical benefit of Cyclosporine A (CsA) in IBD is controversial. Drugs including CsA are substrates of the P-glycoprotein-170 (Pgp-170) cell surface pump. Although the mechanism of action of CsA is complex, we determined that Pgp-170 might be ex
Autor:
William R. Shanahan, Daniel L. Kisner, Mary Beth Bowen-Yacyshyn, C. Frank Bennett, Lawrence D. Jewell, Joseph A. Tami, Bruce R. Yacyshyn
Publikováno v:
Gastroenterology. 114(6)
Intercellular adhesion molecule 1 (ICAM-1) plays an important role in the trafficking and activation of leukocytes and is up-regulated in inflamed mucosa in Crohn's disease. ISIS 2302 is an antisense phosphorothioate oligodeoxynucleotide that inhibit
Publikováno v:
Gastroenterology. 124:A494
Publikováno v:
Gastroenterology. 118:A571
Publikováno v:
Gastroenterology. 118:A1335
Publikováno v:
Gastroenterology. 118:A1335
Autor:
Susanne Acklin, Grant Mcfadden, Mary Beth Bowen-Yacyshyn, Bruce R. Yacyshyn, Norma Yachimec, Alexandra Lucas
Publikováno v:
Gastroenterology. 118:A1335
Publikováno v:
Gastroenterology. 114:A1118