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pro vyhledávání: '"Mary Banks"'
Autor:
Mary Banks
Publikováno v:
Poster Presentations.
Autor:
Mary Banks
Publikováno v:
Poster Presentations.
`I enjoyed and was challenged by reading this book, and learned from, and with, it. It is useful for browsing and for a deeper exploration of chosen topics. It offers a healthy enrichment for all who have a dynamic interest in the external and intern
Autor:
Mary Banks
Publikováno v:
Poster Presentations.
Introduction Traditional hospice delivery of rehabilitation to outpatients and day service attendees involved face-to-face appointments and group sessions. For our organisation, like many others, the COVID-19 pandemic halted this, and became a cataly
Publikováno v:
Cardiovascular Toxicology. 17:487-493
The MEK inhibitor trametinib was approved in 2013 for the treatment of unresectable or metastatic melanoma with a BRAF V600E mutation, the most common pathogenic mutation in melanoma. Trametinib blocks activation of ERK1/2, inhibiting cell proliferat
Publikováno v:
Journal of Empirical Research on Human Research Ethics. 12:150-160
Proposals for research concerning fetal and/or placental tissue may be refused institutional review board (IRB) review, effectively preventing the research from occurring. We conducted an anonymous electronic survey of IRB chairs to determine their a
Autor:
Jonathan H, Fox, Teal, Connor, Megan, Stiles, Jibrin, Kama, Zhen, Lu, Kathryn, Dorsey, Gregory, Lieberman, Gregory, Liebermann, Ellen, Sapp, Robert A, Cherny, Mary, Banks, Irene, Volitakis, Marian, DiFiglia, Oksana, Berezovska, Ashley I, Bush, Steven M, Hersch
Publikováno v:
Journal of Biological Chemistry. 286:18320-18330
Huntington disease (HD) is a progressive neurodegenerative disorder caused by expression of polyglutamine-expanded mutant huntingtin protein (mhtt). Most evidence indicates that soluble mhtt species, rather than insoluble aggregates, are the importan
Publikováno v:
Journal of Empirical Research on Human Research Ethics. 6:33-38
Institutional review boards (IRBs) protect human research subjects by reviewing research to ensure compliance with federal regulations and institutional policies. One of the most important functions of IRBs is to ensure that investigators anticipate,
Autor:
Christina M. Lill, Anne V. Thomas, Bradley T. Hyman, Oksana Berezovska, Lauren Herl, Phill Jones, Mary Banks, Amy Deng, Robert Spoelgen
Publikováno v:
Molecular and Cellular Neuroscience. 41:166-174
Alzheimer's disease is characterized by accumulation of toxic beta-amyloid (Abeta) in the brain and neuronal death. Several mutations in presenilin (PS1) and beta-amyloid precursor protein (APP) associate with an increased Abeta(42/40) ratio. Abeta(4
Autor:
Bradley T. Hyman, Takeshi Kihara, Shun Shimohama, Koichi Ando, Ayae Kinoshita, Takaaki Nishimoto, Christina M. Lill, Ryosuke Takahashi, Mary Banks, Hachiro Sugimoto, Kengo Uemura, Oksana Berezovska, Megumi Asada, Nobuhisa Aoyagi, Masakazu Kubota
Publikováno v:
Journal of Neurochemistry. 108:350-360
In neurons, Presenilin 1(PS1)/gamma-secretase is located at the synapses, bound to N-cadherin. We have previously reported that N-cadherin-mediated cell-cell contact promotes cell-surface expression of PS1/gamma-secretase. We postulated that N-cadher