Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mary B. Sevigny"'
Publikováno v:
Cancer Letters. 443:157-166
SL-1-39 [1-(4-chloro-3-methylphenyl)-3-(4-nitrophenyl)thiourea] is a new flexible heteroarotinoid (Flex-Het) analog derived from the parental compound, SHetA2, previously shown to inhibit cell growth across multiple cancer types. The current study ai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9af47220cab2c38b95eddd00bd430c6
https://doi.org/10.1016/j.canlet.2018.11.022
https://doi.org/10.1016/j.canlet.2018.11.022
Publikováno v:
The FASEB Journal. 35
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ceecf8962cfa368aae2d9b779ea6476
https://doi.org/10.1096/fasebj.2021.35.s1.01710
https://doi.org/10.1096/fasebj.2021.35.s1.01710
Autor:
Maryam M.J. Fallatah, Mary B. Sevigny, Emily Ginn, Jihyun Baek, Hongye Zou, Maggie C. Louie, Shengquan Liu
Publikováno v:
European journal of pharmacology. 862
Flexible heteroarotinoids (Flex-Hets) are compounds with promising anti-cancer activities. SHetA2, a first-generation Flex-Het, has been shown to inhibit the growth of cervical, head and neck, kidney, lung, ovarian, prostate, and breast cancers. Howe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c39a74329797908fc30e99d72119e910
https://pubmed.ncbi.nlm.nih.gov/31494077
https://pubmed.ncbi.nlm.nih.gov/31494077
Publikováno v:
Cancer letters. 408
SL-1-18 (1-(chrysen-6-yl)-3-(4-nitrophenyl)thiourea) is new flexible heteroarotinoid (Flex-Het) analog derived from the parent compound, SHetA2, and our previous study showed comparable activity to SHetA2 in terms of inhibiting ER+ breast cancer cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b431e090ff517a4ef1cc9dc0620d8068
https://pubmed.ncbi.nlm.nih.gov/28844711
https://pubmed.ncbi.nlm.nih.gov/28844711
Publikováno v:
Molecular Carcinogenesis. 54:1014-1025
Cadmium is an environmental carcinogen that usually enters the body at minute concentrations through diet or cigarette smoke and bioaccumulates in soft tissues. In past studies, cadmium has been shown to contribute to the development of more aggressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::490c69850896bfc1c32203c5f2d71bad
https://doi.org/10.1002/mc.22170
https://doi.org/10.1002/mc.22170
Publikováno v:
Pharmacological Research. 65:445-450
Prostanoids play an important role in a variety of physiological and pathophysiological processes including inflammation and cancer. The rate-limiting step in the prostanoid biosynthesis pathway is catalyzed by cyclooxygenase-2 (COX-2). COX-2 exists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee73914e64b3a4b97661c119e6296ceb
https://doi.org/10.1016/j.phrs.2012.01.001
https://doi.org/10.1016/j.phrs.2012.01.001
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials
Background Antimicrobial resistance (AMR) is a major threat to global public health. Medicinal plants have long been used as remedies for infectious diseases by native cultures around the world and have the potential for providing effective treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffe1e64e818e60b412ee1cb7bda30dda
http://europepmc.org/articles/PMC4443625
http://europepmc.org/articles/PMC4443625
Publikováno v:
FEBS Letters. 580:6533-6536
Cyclooxygenase-2 (COX-2) catalyzes the rate-limiting step in the prostanoid biosynthesis pathway, converting arachidonic acid into prostaglandin H2. COX-2 exists as 72 and 74kDa glycoforms, the latter resulting from an additional oligosaccharide chai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc243e356869ef3d5b331cac086ef2c
https://doi.org/10.1016/j.febslet.2006.10.073
https://doi.org/10.1016/j.febslet.2006.10.073
Publikováno v:
Molecular carcinogenesis. 54(10)
Cadmium is an environmental carcinogen that usually enters the body at minute concentrations through diet or cigarette smoke and bioaccumulates in soft tissues. In past studies, cadmium has been shown to contribute to the development of more aggressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::daaea76bafaa78150ed8b79689b8aecd
https://pubmed.ncbi.nlm.nih.gov/24798214
https://pubmed.ncbi.nlm.nih.gov/24798214
Publikováno v:
Proceedings of the National Academy of Sciences. 98:12227-12232
Excessive activation of poly(ADP-ribose) polymerase 1 (PARP1) leads to NAD+depletion and cell death during ischemia and other conditions that generate extensive DNA damage. When activated by DNA strand breaks, PARP1 uses NAD+as substrate to form ADP-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e33dd827686fd9d8e2ce5402560e8b73
https://doi.org/10.1073/pnas.211202598
https://doi.org/10.1073/pnas.211202598