Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Mary Ann Comunale"'
Autor:
Benjamin S. Haslund-Gourley, Kyra Woloszczuk, Jintong Hou, Jennifer Connors, Gina Cusimano, Mathew Bell, Bhavani Taramangalam, Slim Fourati, Nathan Mege, Mariana Bernui, Matthew C. Altman, Florian Krammer, Harm van Bakel, IMPACC Network, Holden T. Maecker, Nadine Rouphael, Joann Diray-Arce, Brian Wigdahl, Michele A. Kutzler, Charles B. Cairns, Elias K. Haddad, Mary Ann Comunale
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract The glycosylation of IgG plays a critical role during human severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, activating immune cells and inducing cytokine production. However, the role of IgM N-glycosylation has not be
Externí odkaz:
https://doaj.org/article/3ec94a3f579544858deda0f8801d626a
Autor:
Benjamin S. Haslund-Gourley, Jintong Hou, Kyra Woloszczuk, Elizabeth J. Horn, George Dempsey, Elias K. Haddad, Brian Wigdahl, Mary Ann Comunale
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104979- (2024)
Summary: Background: Lyme disease is caused by the bacteria Borreliella burgdorferi sensu lato (Bb) transmitted to humans from the bite of an infected Ixodes tick. Current diagnostics for Lyme disease are insensitive at the early disease stage and th
Externí odkaz:
https://doaj.org/article/981e46392c30401ba0e4d12812146b6f
Autor:
Benjamin Samuel Haslund-Gourley, Stéphane Grauzam, Anand S. Mehta, Brian Wigdahl, Mary Ann Comunale
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Lyme disease (LD) infection is caused by Borrelia burgdorferi sensu lato (Bb). Due to the limited presence of this pathogen in the bloodstream in humans, diagnosis of LD relies on seroconversion. Immunoglobulins produced in response to infection are
Externí odkaz:
https://doaj.org/article/5f5afd73120342ac9d2465520f56f12c
Publikováno v:
Diagnostics, Vol 13, Iss 6, p 1016 (2023)
IgG N-glycans are an emerging source of disease-specific biomarkers. Over the last decade, the continued development of glycomic databases and the evolution of glyco-analytic methods have resulted in increased throughput, resolution, and sensitivity.
Externí odkaz:
https://doaj.org/article/017e41d1747744f484469990e79d3d22
Autor:
Anne Lamontagne, Ronald E Long, Mary Ann Comunale, Julie Hafner, Lucy Rodemich-Betesh, Mengjun Wang, Jorge Marrero, Adrian M Di Bisceglie, Timothy Block, Anand Mehta
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e64992 (2013)
Using comparative glycoproteomics, we have previously identified a glycoprotein that is altered in both amount and glycosylation as a function of liver cirrhosis. The altered glycoprotein is an agalactosylated (G0) immunoglobulin G molecule (IgG) tha
Externí odkaz:
https://doaj.org/article/123dffbad5e945eb9837488375a3ae58
Autor:
Mary Ann Comunale, Lucy Rodemich-Betesh, Julie Hafner, Mengjun Wang, Pamela Norton, Adrian M Di Bisceglie, Timothy Block, Anand Mehta
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12419 (2010)
We previously reported increased levels of protein-linked fucosylation with the development of liver cancer and identified many of the proteins containing the altered glycan structures. One such protein is alpha-1-antitrypsin (A1AT). To advance these
Externí odkaz:
https://doaj.org/article/9e5ded36aa8640329d1a8a01ba9583a9
Autor:
Timothy Block, Eiji Miyoshi, Katsuhisa Noda, Alex Koszycki, Lucy Rodemich-Betesh, Mengjun Wang, Mary Ann Comunale, Hongyan Liang, Pamela Norton, Anand Mehta
PDF file, 354KB, N-linked glycosylation of total protein from 16 HCC tissue and adjacent liver tissue pairs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34496f5fe2e153b1c83b7fd3afec4454
https://doi.org/10.1158/1055-9965.22436995.v1
https://doi.org/10.1158/1055-9965.22436995.v1
Autor:
Timothy Block, Eiji Miyoshi, Katsuhisa Noda, Alex Koszycki, Lucy Rodemich-Betesh, Mengjun Wang, Mary Ann Comunale, Hongyan Liang, Pamela Norton, Anand Mehta
Background: Alterations in glycosylation have long been associated with the development of cancer. In the case of primary hepatocellular carcinoma (HCC), one alteration that has often been associated is increased amounts of fucose attached to the N-g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53e4a1e85a3109c74dc58837aaf04c16
https://doi.org/10.1158/1055-9965.c.6515662
https://doi.org/10.1158/1055-9965.c.6515662
Autor:
Anand Mehta, Radoslav Goldman, Timothy Block, Jorge Marrero, Amit G. Singal, Yuko Kono, Charles Swindell, Harmin Herrera, Mary Ann Comunale, Miloslav Sanda, Mengjun Wang
Supplementary Table S1. Patient Characteristics for patients from the University of California at San Diego; Supplementary Table S2. Fitness of algorithms; Supplementary Table S3. Cross validations of potential models; Supplementary Table S4. Statist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd0ff23c7e8edddcc02828bd212038a
https://doi.org/10.1158/1055-9965.22436380
https://doi.org/10.1158/1055-9965.22436380
Autor:
Anand Mehta, Timothy Block, Robert Gish, Adrian M. Di Bisceglie, Jorge Marrero, Andrew Klein, Anne Lamontagne, Julie Hafner, Lucy Rodemich-Betesh, Mengjun Wang, Mary Ann Comunale
Supplementary Figure 1 from Novel Changes in Glycosylation of Serum Apo-J in Patients with Hepatocellular Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bfa1f90a89130c33dec96525c31191d
https://doi.org/10.1158/1055-9965.22435212.v1
https://doi.org/10.1158/1055-9965.22435212.v1