Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Mary A. Mullins"'
Autor:
Ricardo Fuentes, Florence L Marlow, Elliott W Abrams, Hong Zhang, Manami Kobayashi, Tripti Gupta, Lee D Kapp, Zachary DiNardo, Ronald Heller, Ruth Cisternas, Priscila García-Castro, Fabián Segovia-Miranda, Felipe Montecinos-Franjola, William Vought, Charles E Vejnar, Antonio J Giraldez, Mary C Mullins
Publikováno v:
PLoS Genetics, Vol 20, Iss 7, p e1011343 (2024)
Maternally-loaded factors in the egg accumulate during oogenesis and are essential for the acquisition of oocyte and egg developmental competence to ensure the production of viable embryos. However, their molecular nature and functional importance re
Externí odkaz:
https://doaj.org/article/7b554f9630d24ed5ab8a433a491aeb11
Autor:
Gregory R. Gipson, Kristof Nolan, Chandramohan Kattamuri, Alan P. Kenny, Zachary Agricola, Nicole A. Edwards, Joseph Zinski, Magdalena Czepnik, Mary C. Mullins, Aaron M. Zorn, Thomas B. Thompson
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-20 (2023)
Abstract Background Proteins of the TGFβ family, which are largely studied as homodimers, are also known to form heterodimers with biological activity distinct from their component homodimers. For instance, heterodimers of bone morphogenetic protein
Externí odkaz:
https://doaj.org/article/777da4f305fb4a5cbabba5e6f768a74b
Autor:
Yoel Bogoch, Allison Jamieson-Lucy, Charles E. Vejnar, Karine Levy, Antonio J. Giraldez, Mary C. Mullins, Yaniv M. Elkouby
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Oogenesis produces functional eggs and is essential for fertility, embryonic development, and reproduction. The zebrafish ovary is an excellent model to study oogenesis in vertebrates, and recent studies have identified multiple regulators in oocyte
Externí odkaz:
https://doaj.org/article/fe408866b0fe4c6a9451b0820892ae7a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Maternal factors which accumulate and establish oocyte polarity during the early stages of oogenesis play key roles in embryonic development, as well as germ cell formation. However, vertebrate oogenesis, especially early stages of oogenesis, is not
Externí odkaz:
https://doaj.org/article/4d7c4bdcfcb24c4a8a1d199ca5ff22ea
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 9, p e1009422 (2021)
Numerous stages of organismal development rely on the cellular interpretation of gradients of secreted morphogens including members of the Bone Morphogenetic Protein (BMP) family through transmembrane receptors. Early gradients of BMPs drive dorsal/v
Externí odkaz:
https://doaj.org/article/fa9f6624e9504963a9768fc815f313a3
Publikováno v:
PLoS Biology, Vol 19, Iss 1, p e3001059 (2021)
Bone Morphogenetic Protein (BMP) patterns the dorsal-ventral (DV) embryonic axis in all vertebrates, but it is unknown how cells along the DV axis interpret and translate the gradient of BMP signaling into differential gene activation that will give
Externí odkaz:
https://doaj.org/article/144bb1f2de9e4a68b11dd2f3c4311aa5
Publikováno v:
eLife, Vol 9 (2020)
Fibrodysplasia ossificans progressiva (FOP) is a rare human genetic disorder characterized by altered skeletal development and extraskeletal ossification. All cases of FOP are caused by activating mutations in the type I BMP/TGFβ cell surface recept
Externí odkaz:
https://doaj.org/article/4952586b9c5540e4b7c0fcc4db9cd7c6
Autor:
Elliott W Abrams, Ricardo Fuentes, Florence L Marlow, Manami Kobayashi, Hong Zhang, Sumei Lu, Lee Kapp, Shai R Joseph, Amy Kugath, Tripti Gupta, Virginia Lemon, Greg Runke, Amanda A Amodeo, Nadine L Vastenhouw, Mary C Mullins
Publikováno v:
PLoS Genetics, Vol 16, Iss 4, p e1008652 (2020)
Forward genetic screens remain at the forefront of biology as an unbiased approach for discovering and elucidating gene function at the organismal and molecular level. Past mutagenesis screens targeting maternal-effect genes identified a broad spectr
Externí odkaz:
https://doaj.org/article/5a7079db9b6942258bc6e78880fb3d19
Autor:
Allison H. Jamieson-Lucy, Manami Kobayashi, Y. James Aykit, Yaniv M. Elkouby, Matias Escobar-Aguirre, Charles E. Vejnar, Antonio J. Giraldez, Mary C. Mullins
Publikováno v:
Dev Biol
The Balbiani body (Bb) is the first marker of polarity in vertebrate oocytes. The Bb is a conserved structure found in diverse animals including insects, fish, amphibians, and mammals. During early zebrafish oogenesis, the Bb assembles as a transient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::536a3c8bcfcc7c577197323392522ff2
https://doi.org/10.1016/j.ydbio.2022.01.006
https://doi.org/10.1016/j.ydbio.2022.01.006
Autor:
Robyn S. Allen, William D. Jones, Maya Hale, Bailey N. Warder, Eileen M. Shore, Mary C. Mullins
Fibrodysplasia ossificans progressiva (FOP) is a rare human genetic condition characterized by altered skeletal development and extra-skeletal bone formation. All cases of FOP are caused by mutations in the type I BMP receptor geneACVR1that result in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d296ab5c7effe02143390c2d308c7f8
https://doi.org/10.1101/2022.12.01.518722
https://doi.org/10.1101/2022.12.01.518722
