Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mary A. Fivizzani"'
Publikováno v:
Archives of Biochemistry and Biophysics. 209:579-583
1α,25-Difluorovitamin D 3 has been synthesized by reacting 1,25-dihydroxyvitamin D 3 -3-acetate with diethylaminosulfurtrifluoride followed by hydrolysis. Retention of configuration of the fluoro group in this reaction was demonstrated by physical s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6634ddbed42f572f4e2a65d1bae1e0c2
https://doi.org/10.1016/0003-9861(81)90315-5
https://doi.org/10.1016/0003-9861(81)90315-5
Publikováno v:
Journal of Biological Chemistry. 254:2017-2022
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::141ce2c559cb93120e57ad929958b653
https://doi.org/10.1016/s0021-9258(17)37759-1
https://doi.org/10.1016/s0021-9258(17)37759-1
Publikováno v:
Analytical Biochemistry. 96:481-488
A synthesis of radiochemically pure 25-hydroxy[26,27- 3 H]vitamin D 3 with a specific activity of 160 Ci/mmol is reported. The structure and biological activity of the radiolabeled compound was verified by comigration on high-pressure liquid chromato
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8be6a575a6037719071dd7c1a88b172
https://doi.org/10.1016/0003-2697(79)90610-9
https://doi.org/10.1016/0003-2697(79)90610-9
Autor:
Paula H. Stern, Joseph L. Napoli, Heinrich K. Schnoes, Mary A. Fivizzani, Alan H. Hamstra, Hector F. DeLuca
Publikováno v:
Steroids. 32:453-466
1alphaHydroxylated-25-masked-vitamin D3 and analogs were synthesized as probes to help evaluate the role of 25-hydroxyl group in hormone-receptor interactions of 1alpha,25-dihydroxyvitamin D3 (13a). Synthetic work on model systems showed that the ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40d00d8b693e375d78a9fac36d6ab33d
https://doi.org/10.1016/0039-128x(78)90058-2
https://doi.org/10.1016/0039-128x(78)90058-2
Publikováno v:
Tetrahedron Letters. 21:4667-4670
All four possible C-23 and C-25 stereoisomers of the title compound have been synthesized. One of these isomers is identical to the natural product.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9056ca105e3584bbc6e0a731d337300
https://doi.org/10.1016/0040-4039(80)88089-0
https://doi.org/10.1016/0040-4039(80)88089-0
Publikováno v:
Proceedings of the National Academy of Sciences. 78:6173-6175
The three-step conversion of vitamin D analogs to 6-oxo-3,5-cyclovitamin D derivatives followed by reduction with a tritide or deuteride reagent and subsequent cycloreversion gives 6-tritio(deutero)vitamin D derivatives and corresponding 5,6- trans -
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1adec99f7e2379ee19e855206b7cb19
https://doi.org/10.1073/pnas.78.10.6173
https://doi.org/10.1073/pnas.78.10.6173
Autor:
Robert P. Esvelt, Mary A. Fivizzani, Herbert E. Paaren, Heinrich K. Schnoes, Hector F. DeLuca
Publikováno v:
The Journal of Organic Chemistry. 46:456-458
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc9219c86bf792de66967cfc5155de28
https://doi.org/10.1021/jo00315a047
https://doi.org/10.1021/jo00315a047
Publikováno v:
Vitamin D. Basic Research and its Clinical Application
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f14677da82894b17a859b4d13da89857
https://doi.org/10.1515/9783112330029-007
https://doi.org/10.1515/9783112330029-007
Publikováno v:
Archives of biochemistry and biophysics. 197(1)
The chemical synthesis, spectral characterization, and biological activity of vitamin D5 in vitamin D-deficient rats is reported. Vitamin D5 is about 180-fold less active than vitamin D3 in calcification of rachitic cartilage and about 100- to 200-fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef11c238ba87a2316fe6664bfdec1e9
https://pubmed.ncbi.nlm.nih.gov/232394
https://pubmed.ncbi.nlm.nih.gov/232394
Autor:
Mary A. Fivizzani, Hector F. DeLuca, Heinrich K. Schnoes, Joseph L. Napoli, William S. Mellon
Publikováno v:
Biochemistry. 19(11)
The first direct chemical synthesis of radiolabeled 1 alpha,25-dihydroxyvitamin D3 is reported. Unlike all previous syntheses, the new approach does not rely on enzymatic 1 alpha-hydroxylation of radiolabeled precursors. Rather, isotope is introduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40a1b91405146e1aa75000213497052f
https://pubmed.ncbi.nlm.nih.gov/6892993
https://pubmed.ncbi.nlm.nih.gov/6892993