Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Mary A. Brothers"'
Autor:
Robert L. Hoffman, Robert S. Kania, Mary A. Brothers, Jay F. Davies, Rose A. Ferre, Ketan S. Gajiwala, Mingying He, Robert J. Hogan, Kirk Kozminski, Lilian Y. Li, Jonathan W. Lockner, Jihong Lou, Michelle T. Marra, Lennert J. Mitchell, Brion W. Murray, James A. Nieman, Stephen Noell, Simon P. Planken, Thomas Rowe, Kevin Ryan, George J. Smith, James E. Solowiej, Claire M. Steppan, Barbara Taggart
Publikováno v:
Journal of Medicinal Chemistry
The novel coronavirus disease COVID-19 that emerged in 2019 is caused by the virus SARS CoV-2 and named for its close genetic similarity to SARS CoV-1 that caused severe acute respiratory syndrome (SARS) in 2002. Both SARS coronavirus genomes encode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c849279282022a7854304d328352c0f1
Autor:
Robert Hoffman, Robert S. Kania, Mary A. Brothers, Jay F. Davies, Rose A. Ferre, Ketan S. Gajiwala, Mingying He, Robert Jeff Hogan, Kirk Kozminski, Lilian Y. Li, Jonathan W. Lockner, Jihong Lou, Michelle T. Marra, Lennert J. Mitchell J. Mitchell Jr, Brion W. Murray, James A. Nieman, Stephen Noell, Simon P. Planken, Thomas Rowe, Kevin Ryan, George J. Smith III, James E. Solowiej, Claire M. Steppan, Barbara Taggart
The novel coronavirus disease COVID-19 that emerged in 2019 is caused by the virus SARS CoV-2 and named for its close genetic similarity to SARS CoV-1 that caused severe acute respiratory syndrome (SARS) in 2002. Both SARS coronavirus genomes encode
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0278c3250d61c1d99cc6c6ca0a5c4ef7
https://doi.org/10.26434/chemrxiv.12631496
https://doi.org/10.26434/chemrxiv.12631496
Autor:
Stephen E. Webber, Joseph T. Marakovits, Peter S. Dragovich, Thomas J. Prins, Ru Zhou, Shella A. Fuhrman, Amy K. Patick, David A. Matthews, Caroline A. Lee, Babu Srinivasan, Terry Moran, Clifford E. Ford, Mary A. Brothers, James E.V. Harr, James W. Meador, Rose Ann Ferre, Stephen T. Worland
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 11:2683-2686
Novel tripeptidyl C-terminal Michael acceptors with an ester replacement of the P(2)-P(3) amide bond were investigated as irreversible inhibitors of the human rhinovirus (HRV) 3C protease (3CP). When screened against HRV serotype-14 the best compound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84cd8babfe2377fc20d3a80e6c3e1f83
https://doi.org/10.1016/s0960-894x(01)00542-x
https://doi.org/10.1016/s0960-894x(01)00542-x
Autor:
Peter S. Dragovich, Ru Zhou, Stephen E. Webber, Thomas J. Prins, Annette K. Kwok, Koji Okano, Shella A. Fuhrman, Leora S. Zalman, Fausto C. Maldonado, Edward L. Brown, James W. Meador, Amy K. Patick, Clifford E. Ford, Mary A. Brothers, Susan L. Binford, David A. Matthews, Rose Ann Ferre, Stephen T. Worland
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 10:45-48
Tripeptide-derived molecules incorporating C-terminal ketone electrophiles were evaluated as reversible inhibitors of the cysteine-containing human rhinovirus 3C protease (3CP). An optimized example of such compounds displayed potent 3CP inhibition a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::118b1130853fc9d84a6aabe30be23895
https://doi.org/10.1016/s0960-894x(99)00587-9
https://doi.org/10.1016/s0960-894x(99)00587-9
Autor:
Gerald J. Seiler, Mary E. Brothers
Publikováno v:
Economic Botany. 53:273-280
The cultivated sunflower (Helianthus annuus) is one of the four most important annual crops in the world grown for its edible oil. Species of the genusHelianthus served as the ancestral stock for the present cultivated sunflower. The wild relatives a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ffc9f3951c9a16dba7292f437c0235c3
https://doi.org/10.1007/bf02866637
https://doi.org/10.1007/bf02866637
Publikováno v:
Crop Science. 37:51-60
Breeding for a quantitative trait like drought resistance would be facilitated by the development of a method of marker-assisted selection (MAS) that is capable of identifying high performing genotypes in early generations. Two recombinant inbred pop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d45f06504731a5ff29daeea5f62005b2
https://doi.org/10.2135/cropsci1997.0011183x003700010008x
https://doi.org/10.2135/cropsci1997.0011183x003700010008x
Autor:
Andreas Cerny, Patricia Fowler, Mary A. Brothers, Michael Houghton, Hans J. Schlicht, Francis V. Chisari
Publikováno v:
European Journal of Immunology. 25:627-630
We report herein the successful priming of human anti-viral cytotoxic T cells (CTL) in vitro using two induction strategies based on the stimulation of peripheral blood mononuclear cells isolated from uninfected donors with synthetic viral peptides.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2396d6acc976e6d958bcbe8ef1134c1
https://doi.org/10.1002/eji.1830250248
https://doi.org/10.1002/eji.1830250248
Autor:
Amy K. Patick, Mary A. Brothers, Fausto Maldonado, Susan Binford, Oscar Maldonado, Shella Fuhrman, Annkatrin Petersen, George J. Smith, Leora S. Zalman, Leigh Ann Burns-Naas, Jonathan Q. Tran
Publikováno v:
Antimicrobial agents and chemotherapy. 49(6)
(E)-(S)-4-((S)-2-{3-[(5-methyl-isoxazole-3-carbonyl)-amino]-2-oxo-2H-pyridin-1-yl}-pent-4-ynoylamino)-5-((S)-2-oxo-pyrrolidin-3-yl)-pent-2-enoic acid ethyl ester (Compound 1) is a novel, irreversible inhibitor of human rhinovirus (HRV) 3C protease {i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af2423a024660fc6a6d66817ff24c6ba
https://pubmed.ncbi.nlm.nih.gov/15917520
https://pubmed.ncbi.nlm.nih.gov/15917520
Autor:
Robert D. Schreiber, Michael K. Pangburn, Ann B. Bjornson, Mary A. Brothers, Hans J. Müller-Eberhard
Publikováno v:
Clinical Immunology and Immunopathology. 23:335-357
Human polymorphonuclear leukocytes (PMNL) display the ability to bind particles coated with C3b or C3bi in the absence of immunoglobulin. Using highly purified, defined fragments of C3, we have extended the eivdence which indicates that these cells p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d00fe39e85e0318e040cc6e0dd9396f0
https://doi.org/10.1016/0090-1229(82)90119-2
https://doi.org/10.1016/0090-1229(82)90119-2
A C9 related channel forming protein in the cytoplasmic granules of human large granular lymphocytes
Publikováno v:
Bioscience reports. 5(12)
Large granular lymphocytes (LGL) from human blood main-tained in culture for 2 to 6 weeks with IL-2 were found positive in the K562 cell killing assay. The cytoplasmic granules of the LGL were isolated, lysed and the soluble proteins were passed over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af59e2a42b757a4aa56823de6f08a0df
https://pubmed.ncbi.nlm.nih.gov/3830274
https://pubmed.ncbi.nlm.nih.gov/3830274