Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Mary A Elrick"'
Autor:
Katelin N Townsend, Jaeline E Spowart, Hassan Huwait, Sima Eshragh, Nathan R West, Mary A Elrick, Steve E Kalloger, Michael Anglesio, Peter H Watson, David G Huntsman, Julian J Lum
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e82406 (2013)
When T cells infiltrate the tumor environment they encounter a myriad of metabolic stressors including hypoxia. Overcoming the limitations imposed by an inadequate tumor vasculature that contributes to these stressors may be a crucial step to immune
Externí odkaz:
https://doaj.org/article/25328a1534014adf872b302f8c1577c3
Autor:
Mary A. Elrick, Vincent I. Poon, Jillian M. Brandon, Luke R. K. Hughson, Ninan Abraham, Katelin N. Townsend, Izabelle Gadawski, Julian J. Lum, E. John Wherry, Sarah MacPherson, Katrin Schlie, Lindsay DeVorkin, Hélène C. F. Côté, Ashley Westerback, Noboru Mizushima
Publikováno v:
The Journal of Immunology. 194:4277-4286
The activation and expansion of effector CD8+ T cells are essential for controlling viral infections and tumor surveillance. During an immune response, T cells encounter extrinsic and intrinsic factors, including oxidative stress, nutrient availabili