Recovery and stable persistence of chloroquine sensitivity in Plasmodium falciparum parasites after its discontinued use in Northern Uganda

Autor: Betty Balikagala, Miki Sakurai-Yatsushiro, Shin-Ichiro Tachibana, Mie Ikeda, Masato Yamauchi, Osbert T. Katuro, Edward H. Ntege, Makoto Sekihara, Naoyuki Fukuda, Nobuyuki Takahashi, Shouki Yatsushiro, Toshiyuki Mori, Makoto Hirai, Walter Opio, Paul S. Obwoya, Denis A. Anywar, Mary A. Auma, Nirianne M. Q. Palacpac, Takafumi Tsuboi, Emmanuel I. Odongo-Aginya, Eisaku Kimura, Martin Ogwang, Toshihiro Horii, Toshihiro Mita

Publikováno v: Malaria Journal, Vol 19, Iss 1, Pp 1-12 (2020)

Abstract Background Usage of chloroquine was discontinued from the treatment of Plasmodium falciparum infection in almost all endemic regions because of global spread of resistant parasites. Since the first report in Malawi, numerous epidemiological

Externí odkaz: https://doaj.org/article/a30e9925e11f4df196431e86b981ef3e

Field evaluation of the safety, acceptability, and feasibility of early infant male circumcision using the AccuCirc device.

Autor: Robert C Bailey, Irene Nyaboke, Mary Ellen Mackesy-Amiti, Erick Okello, Valentine Pengo, Betha Ochomo, Mary Emmaculate Auma, Simon Were, Stella Ojuok, Evelyne Adoyo, Mildred Adhiambo, Marisa R Young, Rebeca M Plank, Fredrick O Otieno

Publikováno v: PLoS ONE, Vol 13, Iss 2, p e0191501 (2018)

As countries scale up adult voluntary medical male circumcision (VMMC) for HIV prevention, they are looking ahead to long term sustainable strategies, including introduction of early infant male circumcision (EIMC). Although a number of devices for E

Externí odkaz: https://doaj.org/article/e6572c677cfc470d9fc5e90ff039fa4a

Recovery and stable persistence of chloroquine sensitivity in Plasmodium falciparum parasites after its discontinued use in Northern Uganda

Autor: Mary A. Auma, Edward H. Ntege, Toshiyuki Mori, Eisaku Kimura, Shouki Yatsushiro, Osbert T. Katuro, Emmanuel I. Odongo-Aginya, Makoto Sekihara, Makoto Hirai, Martin D. Ogwang, Toshihiro Mita, Naoyuki Fukuda, Toshihiro Horii, Betty Balikagala, Nobuyuki Takahashi, Walter Opio, Takafumi Tsuboi, Masato Yamauchi, Mie Ikeda, Denis A Anywar, Paul S. Obwoya, Miki Sakurai-Yatsushiro, Shin-Ichiro Tachibana, Nirianne Marie Q. Palacpac

Publikováno v: Malaria Journal, Vol 19, Iss 1, Pp 1-12 (2020)
Malaria Journal

Background Usage of chloroquine was discontinued from the treatment of Plasmodium falciparum infection in almost all endemic regions because of global spread of resistant parasites. Since the first report in Malawi, numerous epidemiological studies h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95ff43b7986a9a6f8868e289812a050b
https://doi.org/10.21203/rs.2.17892/v2

Ex vivo susceptibility of Plasmodium falciparum to antimalarial drugs in Northern Uganda

Autor: Toshihiro Mita, Naoyuki Fukuda, Masatoshi Kataoka, Miki Sakurai-Yatsushiro, Shouki Yatsushiro, Osbert T. Katuro, Sakurako Emoto, Toshiyuki Mori, Masato Yamauchi, Muneaki Hashimoto, Makoto Sekihara, Martin D. Ogwang, Mie Ikeda, Makoto Hirai, Denis A Anywar, Walter Opio, Shin-Ichiro Tachibana, Nirianne Marie Q. Palacpac, Mary A. Auma, Toshihiro Horii, Betty Balikagala, Eisaku Kimura, Emmanuel I. Odongo-Aginya, Paul S. Obwoya

Publikováno v: Parasitology International. 81:102277

In Uganda, artemether-lumefantrine was introduced as an artemisinin-based combination therapy (ACT) for malaria in 2006. We have previously reported a moderate decrease in ex vivo efficacy of lumefantrine in Northern Uganda, where we also detected ex

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea19d997f78d77e6e70a12f5612cf10b
https://doi.org/10.1016/j.parint.2020.102277

Derivation and validation of a universal vital assessment (UVA) score: a tool for predicting mortality in adult hospitalised patients in sub-Saharan Africa

Autor: Matthew P. Rubach, Martin Otyek Opio, Shabir Lakhi, Albert Majwala, John A. Crump, Abdallah Amir, Martin P. Grobusch, Laura E. Barnes, Patrick Banura, Christopher C. Moore, John E. Ainsworth, Shevin T. Jacob, John S. Schieffelin, Riley Hazard, Tim Baker, India Wheeler, W. Michael Scheld, Richard Ssekitoleko, John Kellett, Michaëla A. M. Huson, Jamie Rylance, Olamide D Jarrett, Susan A Adakun, Ben Andrews, Kacie J Saulters, Mary A Auma

Publikováno v: BMJ global health, 2(2). BMJ Publishing Group
Moore, C C, Hazard, R, Saulters, K J, Ainsworth, J, Adakun, S A, Amir, A, Andrews, B, Auma, M, Baker, T, Banura, P, Crump, J A, Grobusch, M P, Huson, M A M, Jacob, S T, Jarrett, O D, Kellett, J, Lakhi, S, Majwala, A, Opio, M, Rubach, M P, Rylance, J, Michael Scheld, W, Schieffelin, J, Ssekitoleko, R, Wheeler, I & Barnes, L E 2017, ' Derivation and validation of a universal vital assessment (UVA) score : a tool for predicting mortality in adult hospitalised patients in sub-Saharan Africa ', B M J Global Health, vol. 2, no. 2, e000344 . https://doi.org/10.1136/bmjgh-2017-000344
BMJ Global Health

BACKGROUND: Critical illness is a leading cause of morbidity and mortality in sub-Saharan Africa (SSA). Identifying patients with the highest risk of death could help with resource allocation and clinical decision making. Accordingly, we derived and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc2f7855d82dec0fc8f522fd9b20328
https://doi.org/10.1136/bmjgh-2017-000344