Zobrazeno 1 - 10
of 328
pro vyhledávání: '"Mary A, Allen"'
Autor:
Robert C. Burns, Ross G. Andrew, Danielle Schwarzmann, Mary E. Allen, Jasmine Cardozo Moreira
Publikováno v:
Coasts, Vol 4, Iss 3, Pp 609-618 (2024)
Evaluating the effects of environmental events across both biophysical and social dimensions is important in establishing a holistic view of such events. This study focuses on the impact of a devastating heat stress incident that occurred in many loc
Externí odkaz:
https://doaj.org/article/276ce28bdbed433aa3fee01cce726360
Autor:
Tara O. Henderson, Mary Ashley Allen, Rajia Mim, Brian Egleston, Linda Fleisher, Elena Elkin, Kevin Oeffinger, Kevin Krull, Demetrios Ofidis, Briana Mcleod, Hannah Griffin, Elizabeth Wood, Cara Cacioppo, Michelle Weinberg, Sarah Brown, Sarah Howe, Aaron McDonald, Chris Vukadinovich, Shani Alston, Dayton Rinehart, Gregory T. Armstrong, Angela R. Bradbury
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-18 (2024)
Abstract Background Germline cancer genetic testing has become a standard evidence-based practice, with established risk reduction and screening guidelines for genetic carriers. Access to genetic services is limited in many places, which leaves many
Externí odkaz:
https://doaj.org/article/d1df3aa9eae34e88b2b912237a3cd296
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background The increase in DNA copy number in Down syndrome (DS; caused by trisomy 21) has led to the DNA dosage hypothesis, which posits that the level of gene expression is proportional to the gene’s DNA copy number. Yet many reports hav
Externí odkaz:
https://doaj.org/article/238ef4c8c0f8445d9a5da98a430fd583
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-20 (2023)
Abstract Background RUNX1 is a transcription factor and a master regulator for the specification of the hematopoietic lineage during embryogenesis and postnatal megakaryopoiesis. Mutations and rearrangements on RUNX1 are key drivers of hematological
Externí odkaz:
https://doaj.org/article/94be87776c5746f7bbd9ec462489c35e
Publikováno v:
BMC Research Notes, Vol 16, Iss 1, Pp 1-4 (2023)
Abstract Objectives The glucocorticoid receptor (GR) is a well-studied, ligand-activated transcription factor and a common target of anti-inflammatory treatments. Recently, several studies have drawn attention the effects of binding of GR to RNA rath
Externí odkaz:
https://doaj.org/article/e19431f23b724374b3466764dc2229f5
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0307375 (2024)
Heat shock stress induces genome-wide changes in transcription regulation, activating a coordinated cellular response to enable survival. We noticed many heat shock genes are up-regulated in blood samples from individuals with trisomy 21. We characte
Externí odkaz:
https://doaj.org/article/e9b62ee5f1034911aaaac0be0f2acd27
Autor:
Nickolaus C. Lammer, Humza M. Ashraf, Daniella A. Ugay, Sabrina L. Spencer, Mary A. Allen, Robert T. Batey, Deborah S. Wuttke
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract The glucocorticoid receptor (GR) is a ligand-activated transcription factor that regulates a suite of genes through direct binding of GR to specific DNA promoter elements. GR also interacts with RNA, but the function of this RNA-binding acti
Externí odkaz:
https://doaj.org/article/5fd3b59696db4521b28300ffa680c084
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Background A variety of protocols exist for producing whole genome run-on transcription datasets. However, little is known about how differences between these protocols affect the signal within the resulting libraries. Results Using run-on t
Externí odkaz:
https://doaj.org/article/79d3071ce7be4d67a3e16fea1ce9d445
Autor:
Cierra J. Walker, Dilara Batan, Carrie T. Bishop, Daniel Ramirez, Brian A. Aguado, Megan E. Schroeder, Claudia Crocini, Jessica Schwisow, Karen Moulton, Laura Macdougall, Robert M. Weiss, Mary A. Allen, Robin Dowell, Leslie A. Leinwand, Kristi S. Anseth
Publikováno v:
Bioengineering & Translational Medicine, Vol 7, Iss 3, Pp n/a-n/a (2022)
Abstract Aortic valve stenosis (AVS) is a progressive fibrotic disease that is caused by thickening and stiffening of valve leaflets. At the cellular level, quiescent valve interstitial cells (qVICs) activate to myofibroblasts (aVICs) that persist wi
Externí odkaz:
https://doaj.org/article/7131e16927834fb5a636e98358625fa7
Publikováno v:
Journal of Comparative Social Work, Vol 17, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/9589355deda74deea6bbf49e31714f7d