Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Mary‐Jane L. Ma"'
Autor:
Tingting Xie, Guangya Wang, Spencer C. Ding, Wing-Shan Lee, Suk Hang Cheng, Rebecca W. Y. Chan, Ze Zhou, Mary-Jane L. Ma, Diana S. C. Han, Jeremy Y. C. Teoh, W. K. Jacky Lam, Peiyong Jiang, Rossa W. K. Chiu, K. C. Allen Chan, Y. M. Dennis Lo
Publikováno v:
npj Genomic Medicine, Vol 7, Iss 1, Pp 1-8 (2022)
Abstract Single-stranded ends of double-stranded DNA (jagged ends) are more abundant in urinary DNA than in plasma DNA. However, the lengths of jagged ends in urinary DNA remained undetermined, as a previous method used for urinary DNA jagged end seq
Externí odkaz:
https://doaj.org/article/e4eb0c32fae44646b1cdb1df9e10c7f5
Autor:
Guangya Wang, W K Jacky Lam, Lowell Ling, Mary-Jane L Ma, Saravanan Ramakrishnan, Don C T Chan, Wing-Shan Lee, Suk Hang Cheng, Rebecca W Y Chan, Stephanie C Y Yu, Irene O L Tse, Wai Tat Wong, Peiyong Jiang, Rossa W K Chiu, K C Allen Chan, Y M Dennis Lo
Publikováno v:
Clinical Chemistry. 69:189-201
Background Nuclear-derived cell-free DNA (cfDNA) molecules in blood plasma are nonrandomly fragmented, bearing a wealth of information related to tissues of origin. DNASE1L3 (deoxyribonuclease 1 like 3) is an important player in shaping the fragmenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ca71723b6e355068e4756551eabf03c
https://doi.org/10.1093/clinchem/hvac197
https://doi.org/10.1093/clinchem/hvac197
Autor:
Ze Zhou, Mary-Jane L. Ma, Rebecca W. Y. Chan, W. K. Jacky Lam, Wenlei Peng, Wanxia Gai, Xi Hu, Spencer C. Ding, Lu Ji, Qing Zhou, Peter P. H. Cheung, Stephanie C. Y. Yu, Jeremy Y. C. Teoh, Cheuk-Chun Szeto, John Wong, Vincent W. S. Wong, Grace L. H. Wong, Stephen L. Chan, Edwin P. Hui, Brigette B. Y. Ma, Anthony T. C. Chan, Rossa W. K. Chiu, K. C. Allen Chan, Y. M. Dennis Lo, Peiyong Jiang
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Cell-free DNA (cfDNA) fragmentation is nonrandom, at least partially mediated by various DNA nucleases, forming characteristic cfDNA end motifs. However, there is a paucity of tools for deciphering the relative contributions of cfDNA cleavage pattern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebd9260fa464576f47f0fd91e97cfc65
https://doi.org/10.1073/pnas.2220982120
https://doi.org/10.1073/pnas.2220982120
Autor:
Qing Zhou, Guannan Kang, Peiyong Jiang, Rong Qiao, W. K. Jacky Lam, Stephanie C. Y. Yu, Mary-Jane L. Ma, Lu Ji, Suk Hang Cheng, Wanxia Gai, Wenlei Peng, Huimin Shang, Rebecca W. Y. Chan, Stephen L. Chan, Grace L. H. Wong, Linda T. Hiraki, Stefano Volpi, Vincent W. S. Wong, John Wong, Rossa W. K. Chiu, K. C. Allen Chan, Y. M. Dennis Lo
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Cell-free DNA (cfDNA) fragmentation patterns contain important molecular information linked to tissues of origin. We explored the possibility of using fragmentation patterns to predict cytosine-phosphate-guanine (CpG) methylation of cfDNA, obviating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b97634f42ad78364b56a157180672c8
https://doi.org/10.1073/pnas.2209852119
https://doi.org/10.1073/pnas.2209852119
Autor:
Tingting Xie, Guangya Wang, Spencer C. Ding, Wing-Shan Lee, Suk Hang Cheng, Rebecca W. Y. Chan, Ze Zhou, Mary-Jane L. Ma, Diana S. C. Han, Jeremy Y. C. Teoh, W. K. Jacky Lam, Peiyong Jiang, Rossa W. K. Chiu, K. C. Allen Chan, Y. M. Dennis Lo
Publikováno v:
NPJ genomic medicine. 7(1)
Single-stranded ends of double-stranded DNA (jagged ends) are more abundant in urinary DNA than in plasma DNA. However, the lengths of jagged ends in urinary DNA remained undetermined, as a previous method used for urinary DNA jagged end sequencing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::173c17d1a4b9367e0f3007a8a0d4a3f8
https://pubmed.ncbi.nlm.nih.gov/35197474
https://pubmed.ncbi.nlm.nih.gov/35197474
Autor:
Meihui Chen, Rebecca W. Y. Chan, Peter P. H. Cheung, Meng Ni, Danny K. L. Wong, Ze Zhou, Mary-Jane L. Ma, Liangbo Huang, Xinzhou Xu, Wing-Shan Lee, Guangya Wang, Kathy O. Lui, W. K. Jacky Lam, Jeremy Y. C. Teoh, Chi-Fai Ng, Peiyong Jiang, K. C. Allen Chan, Rossa W. K. Chiu, Y. M. Dennis Lo
Publikováno v:
PLOS Genetics. 18:e1010262
Urinary cell-free DNA (ucfDNA) is a potential biomarker for bladder cancer detection. However, the biological characteristics of ucfDNA are not well understood. We explored the roles of deoxyribonuclease 1 (DNASE1) and deoxyribonuclease 1-like 3 (DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354ee53052e18a845bb7630ac3d982a7
https://doi.org/10.1371/journal.pgen.1010262
https://doi.org/10.1371/journal.pgen.1010262
Autor:
Mary‐Jane L. Ma, Sergey Yakovenko, Haiqiang Zhang, Suk Hang Cheng, Valentina Apryshko, Alex Zhavoronkov, Peiyong Jiang, K. C. Allen Chan, Rossa W. K. Chiu, Y. M. Dennis Lo
Publikováno v:
Prenatal Diagnosis. 41
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c97a652e940c21da5ee2cb8c25e07136
https://doi.org/10.1002/pd.5922
https://doi.org/10.1002/pd.5922
Autor:
Peiyong Jiang, Rossa W.K. Chiu, V.P. Apryshko, Y.M. Dennis Lo, Mary‐Jane L. Ma, S.A. Yakovenko, Haiqiang Zhang, K.C. Allen Chan, Suk Hang Cheng, Alex Zhavoronkov
Publikováno v:
Prenatal Diagnosis
Objectives Due to the maternally‐inherited nature of mitochondrial DNA (mtDNA), there is a lack of information regarding fetal mtDNA in the plasma of pregnant women. We aim to explore the presence and topologic forms of circulating fetal and matern
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454924027aba4c65692f0a72f15ff963
https://pubmed.ncbi.nlm.nih.gov/33539556
https://pubmed.ncbi.nlm.nih.gov/33539556
Autor:
Peiyong Jiang, Wanxia Gai, Haiqiang Zhang, Tak Yeung Leung, John Wong, Suk Hang Cheng, Sarah T K Sin, Mary‐Jane L. Ma, Rossa W.K. Chiu, O Y Olivia Tse, Wing-Shan Lee, Wenlei Peng, Wai Kei Jacky Lam, K.C. Allen Chan, Daljit Singh Sahota, Raymond S.M. Wong, Y.M. Dennis Lo, Radha Raghupathy
Publikováno v:
Clinical chemistry. 65(9)
BACKGROUND Cellular mitochondrial DNA (mtDNA) is organized as circular, covalently closed and double-stranded DNA. Studies have demonstrated the presence of short mtDNA fragments in plasma. It is not known whether circular mtDNA might concurrently ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01093341fd505f62946bca44d5f6714d
https://pubmed.ncbi.nlm.nih.gov/31263037
https://pubmed.ncbi.nlm.nih.gov/31263037