Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Mary, Germino"'
Autor:
Parsa Akbari, Olukayode A. Sosina, Jonas Bovijn, Karl Landheer, Jonas B. Nielsen, Minhee Kim, Senem Aykul, Tanima De, Mary E. Haas, George Hindy, Nan Lin, Ian R. Dinsmore, Jonathan Z. Luo, Stefanie Hectors, Benjamin Geraghty, Mary Germino, Lampros Panagis, Prodromos Parasoglou, Johnathon R. Walls, Gabor Halasz, Gurinder S. Atwal, Regeneron Genetics Center, DiscovEHR Collaboration, Marcus Jones, Michelle G. LeBlanc, Christopher D. Still, David J. Carey, Alice Giontella, Marju Orho-Melander, Jaime Berumen, Pablo Kuri-Morales, Jesus Alegre-Díaz, Jason M. Torres, Jonathan R. Emberson, Rory Collins, Daniel J. Rader, Brian Zambrowicz, Andrew J. Murphy, Suganthi Balasubramanian, John D. Overton, Jeffrey G. Reid, Alan R. Shuldiner, Michael Cantor, Goncalo R. Abecasis, Manuel A. R. Ferreira, Mark W. Sleeman, Viktoria Gusarova, Judith Altarejos, Charles Harris, Aris N. Economides, Vincent Idone, Katia Karalis, Giusy Della Gatta, Tooraj Mirshahi, George D. Yancopoulos, Olle Melander, Jonathan Marchini, Roberto Tapia-Conyer, Adam E. Locke, Aris Baras, Niek Verweij, Luca A. Lotta
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Fat distribution is associated with cardiometabolic disease, although it has been less well studied than overall obesity. In a multiancestry exome-sequencing study, the authors identified predicted loss-of-function mutations in INHBE associated with
Externí odkaz:
https://doaj.org/article/9f24eb7300be4033aaf87fbf13407526
Autor:
Niek Verweij, Mary E. Haas, Jonas B. Nielsen, Olukayode A. Sosina, Minhee Kim, Parsa Akbari, Tanima De, George Hindy, Jonas Bovijn, Trikaldarshi Persaud, Lawrence Miloscio, Mary Germino, Lampros Panagis, Kyoko Watanabe, Joelle Mbatchou, Marcus Jones, Michelle LeBlanc, Suganthi Balasubramanian, Craig Lammert, Sofia Enhörning, Olle Melander, David J. Carey, Christopher D. Still, Tooraj Mirshahi, Daniel J. Rader, Prodromos Parasoglou, Johnathon R. Walls, John D. Overton, Jeffrey G. Reid, Aris Economides, Michael N. Cantor, Brian Zambrowicz, Andrew J. Murphy, Goncalo R. Abecasis, Manuel A.R. Ferreira, Eriks Smagris, Viktoria Gusarova, Mark Sleeman, George D. Yancopoulos, Jonathan Marchini, Hyun M. Kang, Katia Karalis, Alan R. Shuldiner, Giusy Della Gatta, Adam E. Locke, Aris Baras, Luca A. Lotta
Publikováno v:
New England Journal of Medicine. 387:332-344
Autor:
Niek, Verweij, Mary E, Haas, Jonas B, Nielsen, Olukayode A, Sosina, Minhee, Kim, Parsa, Akbari, Tanima, De, George, Hindy, Jonas, Bovijn, Trikaldarshi, Persaud, Lawrence, Miloscio, Mary, Germino, Lampros, Panagis, Kyoko, Watanabe, Joelle, Mbatchou, Marcus, Jones, Michelle, LeBlanc, Suganthi, Balasubramanian, Craig, Lammert, Sofia, Enhörning, Olle, Melander, David J, Carey, Christopher D, Still, Tooraj, Mirshahi, Daniel J, Rader, Prodromos, Parasoglou, Johnathon R, Walls, John D, Overton, Jeffrey G, Reid, Aris, Economides, Michael N, Cantor, Brian, Zambrowicz, Andrew J, Murphy, Goncalo R, Abecasis, Manuel A R, Ferreira, Eriks, Smagris, Viktoria, Gusarova, Mark, Sleeman, George D, Yancopoulos, Jonathan, Marchini, Hyun M, Kang, Katia, Karalis, Alan R, Shuldiner, Giusy, Della Gatta, Adam E, Locke, Aris, Baras, Luca A, Lotta
Publikováno v:
The New England journal of medicine. 387(4)
Exome sequencing in hundreds of thousands of persons may enable the identification of rare protein-coding genetic variants associated with protection from human diseases like liver cirrhosis, providing a strategy for the discovery of new therapeutic
Genome-wide association study of liver fat, iron, and extracellular fluid fraction in the UK Biobank
Autor:
Johnathon R. Walls, Niek Verweij, Manuel A. R. Ferreira, Christian Benner, Nan Lin, Jonathan Marchini, Luca A. Lotta, Ashish Yadav, Gonçalo R. Abecasis, Jonas B. Nielsen, Mary Germino, Colm O'Dushlaine, Aris Baras, Joshua D. Backman, Prodromos Parasoglou
Abdominal magnetic resonance imaging (MRI) represents a non-invasive approach allowing the extraction of clinically informative phenotypes. We developed an automated pipeline to segment liver pixels from abdominal MRI images and apply published model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19047cd0881cdaf0ee3238cf0d660fc9
https://doi.org/10.1101/2021.10.25.21265127
https://doi.org/10.1101/2021.10.25.21265127
Autor:
Xiaoli Zhang, Elizabeth Hwang-Wong, Gannie Tzoneva, Nyanza Rothman, Ajay Bhargava Bhargava, Mary Germino, Lampros Panagis, Alan Shuldiner, Aris Economides, Katherine Cygnar
Publikováno v:
Molecular Genetics and Metabolism. 135:S131
Autor:
Mary Germino, Chi Liu, Tim Mulnix, Richard E. Carson, Yihuan Lu, Kathryn Fontaine, Michael E. Casey
Publikováno v:
IEEE Transactions on Radiation and Plasma Medical Sciences. 2:41-50
With the recent development of high resolution time-of-flight (TOF) positron emission tomography (PET) and resolution recovery incorporated in the reconstruction algorithm, accurate detection, and quantification of sub-centimeter nodules might become
Publikováno v:
Physics in Medicine & Biology. 62:5344-5364
Parametric images for dynamic positron emission tomography (PET) are typically generated by an indirect method, i.e. reconstructing a time series of emission images, then fitting a kinetic model to each voxel time activity curve. Alternatively, 'dire
Autor:
Tianyu Ma, Yaqiang Liu, Chi Liu, Olivia J. Kelada, Mary Germino, Jean-Dominique Gallezot, Yunhan Yu, Chung Chan, Mika Naganawa, Richard E. Carson, Albert J. Sinusas
Publikováno v:
Journal of Nuclear Medicine. 57:1084-1090
Existing respiratory motion-correction methods are applied only to static PET imaging. We have previously developed an event-by-event respiratory motion-correction method with correlations between internal organ motion and external respiratory signal
Autor:
Richard E. Carson, Xenophon Papademetris, Yiqiang Jian, Chi Liu, Chung Chan, John A. Onofrey, Mary Germino
Publikováno v:
IEEE Trans Med Imaging
Respiratory motion during positron emission tomography (PET)/computed tomography (CT) imaging can cause significant image blurring and underestimation of tracer concentration for both static and dynamic studies. In this paper, with the aim to elimina
Autor:
Mary, Germino, Richard E, Carson
Publikováno v:
Medical physics. 45(2)
Cardiac perfusion PET data can be reconstructed as a dynamic sequence and kinetic modeling performed to quantify myocardial blood flow, or reconstructed as static gated images to quantify function. Parametric images from dynamic PET are conventionall