Výsledky vyhledávání - "Mary, Bergwell"

Akademický článek

The chromatin remodeling protein CHD-1 and the EFL-1/DPL-1 transcription factor cooperatively down regulate CDK-2 to control SAS-6 levels and centriole number.

Autor: Jyoti Iyer, Lindsey K Gentry, Mary Bergwell, Amy Smith, Sarah Guagliardo, Peter A Kropp, Prabhu Sankaralingam, Yan Liu, Eric Spooner, Bruce Bowerman, Kevin F O'Connell

Publikováno v: PLoS Genetics, Vol 18, Iss 4, p e1009799 (2022)

Centrioles are submicron-scale, barrel-shaped organelles typically found in pairs, and play important roles in ciliogenesis and bipolar spindle assembly. In general, successful execution of centriole-dependent processes is highly reliant on the abili

Externí odkaz: https://doaj.org/article/5bcfdfa314f642979898e75a381717f3

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A primary microcephaly-associatedsas-6mutation perturbs centrosome duplication, dendrite morphogenesis, and ciliogenesis inCaenorhabditis elegans

Autor: Mary Bergwell, Amy Smith, Ellie Smith, Carter Dierlam, Ramon Duran, Erin Haastrup, Rebekah Napier-Jameson, Rory Seidel, William Potter, Adam Norris, Jyoti Iyer

The human SASS6(I62T) missense mutation has been linked with the incidence of primary microcephaly in a Pakistani family, although the mechanisms by which this mutation causes disease remain unclear. The SASS6(I62T) mutation corresponds to SAS-6(L69T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bbdfdbcef31215f84a2cb064125f271d
https://doi.org/10.1101/2022.11.25.518003

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Abstract B001: Chromatin engineering using a dCas9-based inducible dimerization system

Autor: Mary Bergwell, JinYoung Park, Laura Pistoni, Jacob G. Kirkland

Publikováno v: Cancer Research. 82:B001-B001

Epigenetic cancers lead to tumor progression via oncogene activation, tumor suppressor silencing, cell fate transitions, and genomic instability. Approximately 50% of tumors have alterations in Chromatin regulators. One group of Chromatin regulators,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::41c47e028b59db80362efa59994051f5
https://doi.org/10.1158/1538-7445.cancepi22-b001

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The chromatin remodeling protein CHD-1 and the EFL-1/DPL-1 transcription factor cooperatively down regulate CDK-2 to control SAS-6 levels and centriole number

Autor: Amy Smith, Sarah Guargliardo, Bruce Bowerman, Prabhu Sankaralingam, Kevin F. O’Connell, Eric Spooner, Jyoti Iyer, Peter A. Kropp, Mary Bergwell, Yan Liu, Lindsey Gentry

Publikováno v: PLoS genetics. 18(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64866276d3045e4d9ca60fd7913a71ce
https://pubmed.ncbi.nlm.nih.gov/35377871

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CRISPR/Cas9 Editing of the C. elegans rbm-3.2 Gene using the dpy-10 Co-CRISPR Screening Marker and Assembled Ribonucleoprotein Complexes

Autor: Amy, Smith, Mary, Bergwell, Ellie, Smith, Danita, Mathew, Jyoti, Iyer

Publikováno v: Journal of visualized experiments : JoVE. (166)

The bacterial Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR)/Streptococcus pyogenes CRISPR-associated protein (Cas) system has been harnessed by researchers to study important biologically relevant problems. The unparalleled power

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::239877b66e441624a8ff7b2e361bffd0
https://pubmed.ncbi.nlm.nih.gov/33369608

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CRISPR/Cas9 Editing of the C. elegans rbm-3.2 Gene using the dpy-10 Co-CRISPR Screening Marker and Assembled Ribonucleoprotein Complexes

Autor: Ellie Smith, Jyoti Iyer, Danita Mathew, Amy Smith, Mary Bergwell

Publikováno v: Journal of Visualized Experiments.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be17e28465d144b6beded76d88503b06
https://doi.org/10.3791/62001-v

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