Application of a High-Content Screening Assay Utilizing Primary Human Lung Fibroblasts to Identify Antifibrotic Drugs for Rapid Repurposing in COVID-19 Patients

Autor: Marwick, John A., Elliott, Richard J.R., Longden, James, Makda, Ashraff, Hirani, Nik, Dhaliwal, Kevin, Dawson, John C., Carragher, Neil O. ^*

Publikováno v: In SLAS Discovery October 2021 26(9):1091-1106

A role for phosphoinositol 3–kinase δ in the impairment of glucocorticoid responsiveness in patients with chronic obstructive pulmonary disease

Autor: Marwick, John A., Caramori, Gaetano, Casolari, Paolo, Mazzoni, Federico, Kirkham, Paul A., Adcock, Ian M., Chung, Kian Fan, Papi, Alberto

Publikováno v: In The Journal of Allergy and Clinical Immunology 2010 125(5):1146-1153

High Caesarean Section Rates Among Women Over 30

Autor: Marwick, John C., Lynn, Robert, Weaver, Jane, Statham, Helen, Richards, Martin

Publikováno v: BMJ: British Medical Journal, 2001 Aug 01. 323(7307), 284-285.

Externí odkaz: https://www.jstor.org/stable/25467556

Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-κB activation

Autor: Marwick, John A., Mills, Ross, Kay, Oliver, Michail, Kyriakos, Stephen, Jillian, Rossi, Adriano G., Dransfield, Ian, Hirani, Nikhil

Publikováno v: Cell Death and Disease, Vol 9, Iss 6, Pp 1-13 (2018)
Cell Death & Disease
Marwick, J A, Mills, R, Kay, O, Michail, K, Stephen, J, Rossi, A G, Dransfield, I & Hirani, N 2018, ' Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-κB activation ', Cell Death and Disease, vol. 9, no. 6 . https://doi.org/10.1038/s41419-018-0710-y

Apoptotic cells modulate the function of macrophages to control and resolve inflammation. Here, we show that neutrophils induce a rapid and sustained suppression of NF-κB signalling in the macrophage through a unique regulatory relationship which is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::57363abbdea193bf2b0e33e33e1f53b0
http://link.springer.com/article/10.1038/s41419-018-0710-y

Redox modulation of chromatin remodeling: impact on histone acetylation and deacetylation, NF-κB and pro-inflammatory gene expression

Autor: Rahman, Irfan, Marwick, John, Kirkham, Paul

Publikováno v: In Biochemical Pharmacology 2004 68(6):1255-1267