Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marwan G, Fakih"'
Autor:
Kohei Shitara, Ben George, Julien Taieb, Raghav Sundar, Marwan G. Fakih, Lukas Makris, Karim A. Benhadji, Michele Ghidini
Publikováno v:
Journal of Cancer Research and Clinical Oncology.
Background In the phase III TAGS trial, trifluridine/tipiracil showed survival benefit versus placebo in patients with metastatic gastric/gastroesophageal junction cancer and ≥ 2 prior chemotherapies. This post hoc exploratory analysis assessed the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fbb3b754887eed1ed860d45ef39449f
https://doi.org/10.1007/s00432-023-04813-z
https://doi.org/10.1007/s00432-023-04813-z
Autor:
Marwan G Fakih, Scott Kopetz, Yasutoshi Kuboki, Tae Won Kim, Pamela N Munster, John C Krauss, Gerald S Falchook, Sae-Won Han, Volker Heinemann, Kei Muro, John H Strickler, David S Hong, Crystal S Denlinger, Gustavo Girotto, Myung-Ah Lee, Haby Henary, Qui Tran, Joseph K Park, Gataree Ngarmchamnanrith, Hans Prenen, Timothy J Price
Publikováno v:
The lancet oncology
Background Sotorasib, a specific, irreversible KRAS(G12C) protein inhibitor, has shown monotherapy clinical activity in KRAS(G12C)-mutated solid tumours, including colorectal cancer, in the CodeBreaK100 phase 1 trial. We aimed to investigate the acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c8895175769c7fb8e15873f4aba538
https://doi.org/10.1016/s1470-2045(21)00605-7
https://doi.org/10.1016/s1470-2045(21)00605-7
Autor:
Xu Cao, Jing Chen, Bolei Li, Jessica Dang, Wencan Zhang, Xiancai Zhong, Chongkai Wang, Mustafa Raoof, Zuoming Sun, Jianhua Yu, Marwan G. Fakih, Mingye Feng
Publikováno v:
Science advances. 8(11)
Macrophages are essential in eliciting antibody-dependent cellular phagocytosis (ADCP) of cancer cells. However, a satisfactory anticancer efficacy of ADCP is contingent on early antibody administration, and resistance develops along with cancer prog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd957650bb92e5ef8c096ad028e4e53e
https://pubmed.ncbi.nlm.nih.gov/35302839
https://pubmed.ncbi.nlm.nih.gov/35302839
Autor:
Marwan G, Fakih, Scott, Kopetz, Yasutoshi, Kuboki, Tae Won, Kim, Pamela N, Munster, John C, Krauss, Gerald S, Falchook, Sae-Won, Han, Volker, Heinemann, Kei, Muro, John H, Strickler, David S, Hong, Crystal S, Denlinger, Gustavo, Girotto, Myung-Ah, Lee, Haby, Henary, Qui, Tran, Joseph K, Park, Gataree, Ngarmchamnanrith, Hans, Prenen, Timothy J, Price
Publikováno v:
The Lancet. Oncology. 23(1)
Sotorasib, a specific, irreversible KRASIn this single-arm, phase 2 trial, adult patients with KRASOn March 1, 2021, at data cutoff, 62 patients with KRASAlthough the 9·7% overall response rate did not reach the benchmark, oral administration of sot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d53dff7a2dc4bf536cbbd15c594e55c2
https://pubmed.ncbi.nlm.nih.gov/34987029
https://pubmed.ncbi.nlm.nih.gov/34987029
Autor:
Muhammad Wasif, Saif, Carlos R, Becerra, Marwan G, Fakih, Weijing, Sun, Lazar, Popovic, Smitha, Krishnamurthi, Thomas J, George, Michelle A, Rudek, Dale R, Shepard, Jiri, Skopek, Vladimir, Sramek, Bojan, Zaric, Ikuo, Yamamiya, Karim A, Benhadji, Kensuke, Hamada, Yaohua, He, Lee, Rosen
Publikováno v:
Cancer chemotherapy and pharmacology. 88(3)
Trifluridine/tipiracil (FTD/TPI) is approved for advanced colorectal and gastric/gastroesophageal cancer; however, data in patients with renal impairment (RI) are limited. This phase I study evaluated FTD/TPI in patients with advanced solid tumors an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::63892e1e81c01f25ce26f2eaf9713941
https://pubmed.ncbi.nlm.nih.gov/34097100
https://pubmed.ncbi.nlm.nih.gov/34097100
Autor:
Niharika B. Mettu, Fang-Shu Ou, Tyler J. Zemla, Thorvardur R. Halfdanarson, Heinz-Josef Lenz, Rimini A. Breakstone, Patrick M. Boland, Oxana V. Crysler, Christina Wu, Andrew B. Nixon, Emily Bolch, Donna Niedzwiecki, Alicia Elsing, Herbert I. Hurwitz, Marwan G. Fakih, Tanios Bekaii-Saab
Publikováno v:
JAMA Network Open. 5:e2149040
Cotargeting vascular endothelial growth factor and programmed cell death 1 or programmed cell death ligand 1 may produce anticancer activity in refractory metastatic colorectal cancer (mCRC). The clinical benefit of atezolizumab combined with chemoth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a02ac29f0a9daccf92b8553966c10794
https://doi.org/10.1001/jamanetworkopen.2021.49040
https://doi.org/10.1001/jamanetworkopen.2021.49040
Autor:
Chongkai Wang, John Park, Ching Ouyang, Raju Pillai, Jeffrey Longmate, Holly Yin, Christian Avalos, Maricel Gozo, Colt Egelston, Peter P. Lee, Marwan G. Fakih
Publikováno v:
Cancer Research. 79:528-528
Introduction: PD-1 inhibitors have been ineffective in microsatellite stable (MSS) metastatic colorectal cancer (mCRC). Preclinical models suggest that radiation therapy may sensitize MSS CRC to PD-1 blockade. This constitutes the rationale for combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8d23a230e2365778fcc49340382e37f
https://doi.org/10.1158/1538-7445.am2019-528
https://doi.org/10.1158/1538-7445.am2019-528
Autor:
Jaffer A, Ajani, David J, Bentrem, Stephen, Besh, Thomas A, D'Amico, Prajnan, Das, Crystal, Denlinger, Marwan G, Fakih, Charles S, Fuchs, Hans, Gerdes, Robert E, Glasgow, James A, Hayman, Wayne L, Hofstetter, David H, Ilson, Rajesh N, Keswani, Lawrence R, Kleinberg, W Michael, Korn, A Craig, Lockhart, Kenneth, Meredith, Mary F, Mulcahy, Mark B, Orringer, James A, Posey, Aaron R, Sasson, Walter J, Scott, Vivian E, Strong, Thomas K, Varghese, Graham, Warren, Mary Kay, Washington, Christopher, Willett, Cameron D, Wright, Nicole R, McMillian, Hema, Sundar
Publikováno v:
Journal of the National Comprehensive Cancer Network : JNCCN. 11(5)
The NCCN Clinical Practice Guidelines in Oncology for Gastric Cancer provide evidence- and consensus-based recommendations for a multidisciplinary approach for the management of patients with gastric cancer. For patients with resectable locoregional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fab996cd18211c4495752cbb92e7baf9
https://pubmed.ncbi.nlm.nih.gov/23667204
https://pubmed.ncbi.nlm.nih.gov/23667204
Autor:
Al B, Benson, Tanios, Bekaii-Saab, Emily, Chan, Yi-Jen, Chen, Michael A, Choti, Harry S, Cooper, Paul F, Engstrom, Peter C, Enzinger, Marwan G, Fakih, Moon J, Fenton, Charles S, Fuchs, Jean L, Grem, Steven, Hunt, Ahmed, Kamel, Lucille A, Leong, Edward, Lin, Kilian Salerno, May, Mary F, Mulcahy, Kate, Murphy, Eric, Rohren, David P, Ryan, Leonard, Saltz, Sunil, Sharma, David, Shibata, John M, Skibber, William, Small, Constantinos T, Sofocleous, Alan P, Venook, Christopher G, Willett, Kristina M, Gregory, Deborah A, Freedman-Cass
Publikováno v:
Journal of the National Comprehensive Cancer Network : JNCCN. 11(5)
The NCCN Clinical Practice Guidelines in Oncology for Colon Cancer begin with the clinical presentation of the patient to the primary care physician or gastroenterologist and address diagnosis, pathologic staging, surgical management, perioperative t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::27162ec536ba9e060e0f7946abe3ec1b
https://pubmed.ncbi.nlm.nih.gov/23667203
https://pubmed.ncbi.nlm.nih.gov/23667203
Autor:
Pooja P, Advani, Marwan G, Fakih
Publikováno v:
Anticancer research. 31(1)
Neurological complications of both fluorouracil (5-FU) and its oral prodrug, capecitabine, have been described in the literature. This study reported the case of a 70-year-old female with metastatic adenocarcinoid of the rectum who developed hyperamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::338bd9f45bb095a79a42f2cf48e62836
https://pubmed.ncbi.nlm.nih.gov/21273620
https://pubmed.ncbi.nlm.nih.gov/21273620