Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Marwa O. El-Derany"'
Autor:
Hany N. Azzam, Marwa O. El-Derany, Sara A. Wahdan, Reham M. Faheim, Gouda K. Helal, Ebtehal El-Demerdash
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract We sought in our cross-sectional study to investigate the role of metabolic/hypoxial axis in the development of tamoxifen (TMX) resistance in BC patients. Quantification of plasma LncRNA Taurine upregulated-1 (TUG-1), miRNA 186-5p (miR-186),
Externí odkaz:
https://doaj.org/article/50bf80bedb1f42b3bbb85e9fc2b1511e
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-23 (2021)
Abstract Background Doxorubicin (DOX), a widely used chemotherapeutic agent, can cause neurodegeneration in the brain, which leads to a condition known as chemobrain. In fact, chemobrain is a deteriorating condition which adversely affects the lives
Externí odkaz:
https://doaj.org/article/cbc843482bfe4acd953ca78840affa0e
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 210 (2022)
With the rising incidence of hepatocellular carcinoma (HCC) from non-alcoholic steatohepatitis (NASH), identifying new metabolic readouts that function in metabolic pathway perpetuation is still a demand. The study aimed to compare the metabolic sign
Externí odkaz:
https://doaj.org/article/432292c0d83a4ba19e12a6718bfac73f
Autor:
Heba H. Awad, Marwa O. El-Derany, Eman M. Mantawy, Haidy E. Michel, Mona M. El-Naa, Rania A. Salah El-Din, Amany I. El-Brairy, Ebtehal El-Demerdash
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 140, Iss , Pp 111679- (2021)
The use of doxorubicin (DOX) to treat various tumors is limited by its cardiotoxicity. This study aimed to investigate and compare the cardioprotective effects of nicotinamide (NAM) and alfacalcidol (1α(OH)D3), against DOX-induced cardiotoxicity. Sp
Externí odkaz:
https://doaj.org/article/5bc9bcd4fbe648a0bbaed7132d4d8cb0
Publikováno v:
Life, Vol 12, Iss 3, p 355 (2022)
Cardiovascular-disease (CVD)-related mortality has been fueled by the upsurge of non-alcoholic steatohepatitis (NASH). Mesenchymal stem cells (MSCs) were extensively studied for their reparative power in ameliorating different CVDs via direct and par
Externí odkaz:
https://doaj.org/article/99c7f6343cdb4b3bb6f9e001cf0112ab
Autor:
Marwa O. El-Derany
Publikováno v:
Biology, Vol 9, Iss 4, p 75 (2020)
Background: non-alcoholic steatohepatitis (NASH) recently headlined hepatocellular carcinoma (HCC) worldwide. This study aims to unveil the role of some unaddressed critical players that might aid in understanding, predicting, and targeting NASH and
Externí odkaz:
https://doaj.org/article/2807d38dca7049b5b81b4c4a2baf80a9
Autor:
Enas Elmowafy, Marwa O. El-Derany, Francesca Biondo, Mattia Tiboni, Luca Casettari, Mahmoud E. Soliman
Publikováno v:
Pharmaceutics, Vol 12, Iss 2, p 143 (2020)
Flavonoids possess different interesting biological properties, including antibacterial, antiviral, anti-inflammatory and antioxidant activities. However, unfortunately, these molecules present different bottlenecks, such as low aqueous solubility, p
Externí odkaz:
https://doaj.org/article/e7a7dd0fd69043d3ac086bfe707ad32d
Publikováno v:
Molecular and Cellular Biochemistry.
Non-alcoholic fatty liver (NAFLD) is a widespread disease with various complications including Non-alcoholic steatohepatitis (NASH) that could lead to cirrhosis and ultimately hepatocellular carcinoma (HCC). Up till now there is no FDA approved drug
Autor:
Mina Y. George, Marwa O. El-Derany, Yasmine Ahmed, Malvina Zaher, Caroline Ibrahim, Habiba Waleed, Hajar Khaled, Gehad Khaled, Ahmed Saleh, Huda Alshafei, Rahma Alshafei, Nirmeen Ahmed, Sara Ezz, Nouran Ashraf, Shaimaa S. Ibrahim
Publikováno v:
Expert opinion on drug delivery.
The present study aims to formulate and evaluate the efficacy of chrysin-loaded nanoemulsion (CH NE) against lithium/pilocarpine-induced epilepsy in rats, as well as, elucidate its effect on main epilepsy pathogenesis cornerstones; neuronal hyperacti
Autor:
Hannah N. Bell, Amanda K. Huber, Rashi Singhal, Navyateja Korimerla, Ryan J. Rebernick, Roshan Kumar, Marwa O. El-derany, Peter Sajjakulnukit, Nupur K. Das, Samuel A. Kerk, Sumeet Solanki, Jadyn G. James, Donghwan Kim, Li Zhang, Brandon Chen, Rohit Mehra, Timothy L. Frankel, Balázs Győrffy, Eric R. Fearon, Marina Pasca di Magliano, Frank J. Gonzalez, Ruma Banerjee, Daniel R. Wahl, Costas A. Lyssiotis, Michael Green, Yatrik M. Shah
Publikováno v:
Cell metabolism. 35(1)
Effective therapies are lacking for patients with advanced colorectal cancer (CRC). The CRC tumor microenvironment has elevated metabolic waste products due to altered metabolism and proximity to the microbiota. The role of metabolite waste in tumor