Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Marwa M, Safar"'
Autor:
Afaf A. El-Malah, Magdy M. Gineinah, Maan T. Khayat, Anfal S. Aljahdali, Marwa M. Safar, Hadeel A. Almazmumi, Roaa M. Khinkar
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Phosphodiesterase 7 (PDE7) is a high-affinity cyclic AMP (cAMP)-specific PDE that is expressed in immune and proinflammatory cells. In this work, we explore the possibility that selective small molecule inhibitors of this enzyme family
Externí odkaz:
https://doaj.org/article/217017829d4d45538e0140485c4c4db3
Autor:
Sayed H. Seif el-Din, Olfat A. Hammam, Shahira M. Ezzat, Samira Saleh, Marwa M. Safar, Walaa H. El-Maadawy, Naglaa M. El-Lakkany
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 13, Iss 8, Pp 348-358 (2023)
Objective: To evaluate the effect of hydroxysafflor yellow A (HSYA) on thioacetamide-induced liver fibrosis. Methods: Thioacetamide was administered to rats intraperitoneally in doses of 200 mg/kg twice a week for 12 weeks. Thioacetamide-intoxicated
Externí odkaz:
https://doaj.org/article/5ab834bfb0f14d9eba207c65580cd984
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 366-375 (2021)
Chloroquine (CQ); a lysosomotropic agent used for decade ago as anti-malarial, was tested against aging induced osteoporosis. Osteoporosis in male rats was induced using d-galactose (D-gal) as a reducing sugar at a dose of 200 mg/kg/day; i.p. Osteopo
Externí odkaz:
https://doaj.org/article/d4e7fc50e7364443b1d3a8b18e5f662e
Publikováno v:
Journal of Advanced Research, Vol 18, Iss , Pp 101-112 (2019)
Epilepsy is one of the most well-known neurological conditions worldwide. One-third of adult epileptic patients do not respond to antiepileptic drugs or surgical treatment and therefore suffer from the resistant type of epilepsy. Stem cells have been
Externí odkaz:
https://doaj.org/article/69760cdfdfa548cba79de78e5800e363
Autor:
Naglaa M. El-Lakkany, Walaa H. El-Maadawy, Sayed H. Seif el-Din, Samira Saleh, Marwa M. Safar, Shahira M. Ezzat, Salwa H. Mohamed, Sanaa S. Botros, Zeinab Demerdash, Olfat A. Hammam
Publikováno v:
Journal of Traditional and Complementary Medicine, Vol 9, Iss 1, Pp 45-53 (2019)
Few studies reported the antifibrotic effects of gallic acid (GA) despite its known hepatoprotective and antioxidant activities. Accordingly, this study investigated the antifibrotic effects of GA through clarifying its mechanisms on hepatic stellate
Externí odkaz:
https://doaj.org/article/e5e8fb9dcbef4baa94cfd80d1ee19cb9
Publikováno v:
Molecular Neurobiology. 59:7194-7211
Global cerebral ischemia/reperfusion (I/R) provokes inflammation that augments neuropathic pain. Cilostazol (CLZ) has pleiotropic effects including neuroprotection in several ravaging central disorders; nonetheless, its potential role in transient ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0c0bfd9127960cc9a4749467e89049c
https://doi.org/10.1007/s12035-022-03024-w
https://doi.org/10.1007/s12035-022-03024-w
Publikováno v:
Inflammopharmacology. 30:2477-2488
The most prevalent type of dementia is Alzheimer's disease (AD), which is currently incurable. Existing treatments for Alzheimer's disease, such as acetylcholinesterase inhibitors, are only effective for symptom relief. Disease-modifying medications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0a2bae813f609bb4ece78e4ce7208d
https://doi.org/10.1007/s10787-022-01010-1
https://doi.org/10.1007/s10787-022-01010-1
Publikováno v:
Inflammopharmacology. 30:919-934
The heterogeneous nature of multiple sclerosis (MS) and the unavailability of treatments addressing its intricate network and reversing the disease state is yet an area that needs to be elucidated. Liraglutide, a glucagon-like peptide-1 analogue, rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::415d59f5041724a252dfb193b26f28c9
https://doi.org/10.1007/s10787-022-00956-6
https://doi.org/10.1007/s10787-022-00956-6
Autor:
Sayed H. Seif el-Din, Marwa M. Safar, Shahira M. Ezzat, Samira Saleh, Naglaa M. El-Lakkany, Walaa H. El-Maadawy, Olfat Hammam
Publikováno v:
Journal of Herbs, Spices & Medicinal Plants. 27:322-341
Despite rutin, extracted from black mulberry, has several pharmacological activities, its exact effect against hepatic fibrosis remains incompletely identified. Accordingly, this study investigates...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11fa4ee34d985263862b5c34b44f71b6
https://doi.org/10.1080/10496475.2021.1911905
https://doi.org/10.1080/10496475.2021.1911905
Publikováno v:
ACS Chemical Neuroscience. 12:689-703
Dapagliflozin, a selective sodium-glucose co-transporter 2 (SGLT2) inhibitor, has emerged as a promising neuroprotective agent in murine models of epilepsy and obesity-induced cognitive impairment through its marked antioxidant/antiapoptotic features
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0db0b4a5bcc34d9199f9a8ef948786ab
https://doi.org/10.1021/acschemneuro.0c00722
https://doi.org/10.1021/acschemneuro.0c00722