Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Marwa H Saied"'
Autor:
Marwa H Saied, Jacek Marzec, Sabah Khalid, Paul Smith, Thomas A Down, Vardhman K Rakyan, Gael Molloy, Manoj Raghavan, Silvana Debernardi, Bryan D Young
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33213 (2012)
Methylated DNA immunoprecipitation followed by high-throughput sequencing (MeDIP-seq) has the potential to identify changes in DNA methylation important in cancer development. In order to understand the role of epigenetic modulation in the developmen
Externí odkaz:
https://doaj.org/article/8f5cb6cc5dc94ac5b2f9e654bcbd677e
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-12 (2023)
Abstract Background HER2-positive breast cancer occurs in 15–20% of breast cancer patients and is characterized by poor prognosis. Trastuzumab is considered the key drug for treatment of HER2-positive breast cancer patients. It improves patient sur
Externí odkaz:
https://doaj.org/article/78b91233be6f48c0bc9b1205e671c285
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 23, Iss 1, Pp 1-9 (2022)
Abstract Background Ovarian cancer (OC) is considered a leading cause of death among women with gynecological malignancies. OC, like breast cancer, shows a familial predisposition to germline mutations in genes BRCA1 or BRCA2, which have proved to pl
Externí odkaz:
https://doaj.org/article/247922d45a754f96991fdba0b6ea46b5
Autor:
Detlef Bockenhauer, François Dragon, Christelle Arrondel, Ákos Szekeres, Kristóf Perczel, Wei-Li Di, Susanne Motameny, Attila Fintha, Maria Kolatsi-Joannou, Eszter Jávorszky, Guillaume Dorval, Salah Marzouk, Kazunori Tomita, Jennifer C. Chandler, Peter Nürnberg, Gusztáv Schay, Veronica A. Kinsler, Ahmed Hossain, Andrea Kerti, András Perczel, Hafsa Hammid, Magdolna Kardos, William Mifsud, Florentina Sava, David Curtis, Corinne Antignac, Felipe D’Arco, Aoife M. Waters, Géraldine Mollet, Mona Tahoun, Gergely Toldi, Tivadar Tulassay, Ana Faro, Anna Szőcs, Jutta Koeglmeier, Kata Kelen, Marwa H. Saied, Holger Thiele, Hywel Williams, Kálmán Tory, Renáta Hamar, Erika Maka, Mario Kaliakatsos, Mariya Moosajee, Gábor Rudas, Máté Varga, Eszter Balogh, Attila Szabo, Dóra K. Menyhárd, Horia Stanescu, Tomas Goncalves, Olivier Gribouval, Regina Légrádi, George S. Reusz, Robert Kleta, Judit Götze, David A. Long
Publikováno v:
Proceedings of the National Academy of Sciences. 117:15137-15147
RNA modifications play a fundamental role in cellular function. Pseudouridylation, the most abundant RNA modification, is catalyzed by the H/ACA small ribonucleoprotein (snoRNP) complex that shares four core proteins, dyskerin (DKC1), NOP10, NHP2, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48c70950ec857554bf1e04d93236b91c
https://doi.org/10.1073/pnas.2002328117
https://doi.org/10.1073/pnas.2002328117
Autor:
Randal Stronge, Paul Smith, Simon P. Joel, Marwa H. Saied, Lola Koniali, Adedayo Oke, David Taussig, Bryan D. Young, Farideh Miraki-Moud, Essam Ghazaly, Janet Matthews, John G. Gribben, Robert D. Petty, Chathunissa Gnanaranjan
Publikováno v:
The Journal of Biological Chemistry
Previous studies have shown that sphingosine kinase interacting protein (SKIP) inhibits sphingosine kinase (SK) function in fibroblasts. SK phosphorylates sphingosine producing the potent signaling molecule sphingosine-1-phosphate (S1P). SKIP gene (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f9a1747fce13819719b027b13c282b
https://doi.org/10.1074/jbc.ra119.010467
https://doi.org/10.1074/jbc.ra119.010467
Publikováno v:
Asian Pacific Journal of Cancer Prevention : APJCP
Background: Up to half of the heritable mutations in breast cancer (BC) are attributed to BRCA1 and BRCA2 genes. The mutation prevalence is variable based on ethnicity and may be influenced by founder mutations. The aim of this pilot study is to dete
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36acc994ebec3cf3e388360450e025b2
https://doi.org/10.31557/apjcp.2020.21.2.431
https://doi.org/10.31557/apjcp.2020.21.2.431
Autor:
Mona Tahoun, Reham Fadl, Inas Ibrahim, Dalal El-Kaffash, Alyaa Elkayal, Marwa H. Saied, Reham Abdel Haleem, Amal Refeat, Eman Tayae
Publikováno v:
Molecular Medicine Reports. 24
Breast cancer (BC) is the most commonly diagnosed cancer worldwide and a major health concern in Egypt. There is a known association between pathogenic variants identified in breast cancer susceptibility gene (BRCA)1 and 2 and the risk of developing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7684688cf64c0a8975c7b3ce67a64f64
https://doi.org/10.3892/mmr.2021.12317
https://doi.org/10.3892/mmr.2021.12317
Autor:
Marwa H, Saied, Dalal, Elkaffash, Reham, Fadl, Reham Abdel, Haleem, Amal, Refeat, Inas, Ibrahim, Mona, Tahoun, Alyaa, Elkayal, Eman, Tayae
Publikováno v:
Molecular medicine reports. 24(3)
Breast cancer (BC) is the most commonly diagnosed cancer worldwide and a major health concern in Egypt. There is a known association between pathogenic variants identified in breast cancer susceptibility gene (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::357d1bb1c558ddb26359a3a2da53566f
https://pubmed.ncbi.nlm.nih.gov/34296289
https://pubmed.ncbi.nlm.nih.gov/34296289
Autor:
Detlef Bockenhauer, Salah Marzouk, Marwa H. Saied, Aoife M. Waters, Mona Tahoun, Jeffrey H. Miner, Mehul T. Dattani, Meei Hua Lin, Ji Soo Kim, Emma Ashton, Felipe D’Arco, Scott Haston, Athia Hannan, G. Anderson, Jennifer C. Chandler
Publikováno v:
The Journal of Clinical Endocrinology and Metabolism
Context Mutations in LAMB2, encoding the basement membrane protein, laminin β2, are associated with an autosomal recessive disorder characterized by congenital nephrotic syndrome, ocular abnormalities, and neurodevelopmental delay (Pierson syndrome)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::030d0f0ca46b9f88232afe4144c608b6
https://doi.org/10.1530/ey.17.1.3
https://doi.org/10.1530/ey.17.1.3
Autor:
Eszter, Balogh, Jennifer C, Chandler, Máté, Varga, Mona, Tahoun, Dóra K, Menyhárd, Gusztáv, Schay, Tomas, Goncalves, Renáta, Hamar, Regina, Légrádi, Ákos, Szekeres, Olivier, Gribouval, Robert, Kleta, Horia, Stanescu, Detlef, Bockenhauer, Andrea, Kerti, Hywel, Williams, Veronica, Kinsler, Wei-Li, Di, David, Curtis, Maria, Kolatsi-Joannou, Hafsa, Hammid, Anna, Szőcs, Kristóf, Perczel, Erika, Maka, Gergely, Toldi, Florentina, Sava, Christelle, Arrondel, Magdolna, Kardos, Attila, Fintha, Ahmed, Hossain, Felipe, D'Arco, Mario, Kaliakatsos, Jutta, Koeglmeier, William, Mifsud, Mariya, Moosajee, Ana, Faro, Eszter, Jávorszky, Gábor, Rudas, Marwa H, Saied, Salah, Marzouk, Kata, Kelen, Judit, Götze, George, Reusz, Tivadar, Tulassay, François, Dragon, Géraldine, Mollet, Susanne, Motameny, Holger, Thiele, Guillaume, Dorval, Peter, Nürnberg, András, Perczel, Attila J, Szabó, David A, Long, Kazunori, Tomita, Corinne, Antignac, Aoife M, Waters, Kálmán, Tory
Publikováno v:
Proc Natl Acad Sci U S A
RNA modifications play a fundamental role in cellular function. Pseudouridylation, the most abundant RNA modification, is catalyzed by the H/ACA small ribonucleoprotein (snoRNP) complex that shares four core proteins, dyskerin (DKC1), NOP10, NHP2, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ed9767392e180665c2cb7a1e6caf982d
https://pubmed.ncbi.nlm.nih.gov/32554502
https://pubmed.ncbi.nlm.nih.gov/32554502