Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Marwa Asem"'
Autor:
Elizabeth A. Loughran, Annemarie K. Leonard, Tyvette S. Hilliard, Ryan C. Phan, Madeleine G. Yemc, Elizabeth Harper, Emma Sheedy, Yuliya Klymenko, Marwa Asem, Yueying Liu, Jing Yang, Jeff Johnson, Laura Tarwater, Zonggao Shi, Matthew Leevy, Matthew J. Ravosa, M. Sharon Stack
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 6, Pp 621-631 (2018)
Ovarian cancer, the most deadly gynecological malignancy in U.S. women, metastasizes uniquely, spreading through the peritoneal cavity and often generating widespread metastatic sites before diagnosis. The vast majority of ovarian cancer cases occur
Externí odkaz:
https://doaj.org/article/7305e2f963ef43069277414c762acb6f
Autor:
Tyvette S. Hilliard, Brooke Kowalski, Kyle Iwamoto, Elizabeth A. Agadi, Yueying Liu, Jing Yang, Marwa Asem, Yuliya Klymenko, Jeff Johnson, Zonggao Shi, Gifty Marfowaa, Madeleine G. Yemc, Phillip Petrasko, M. Sharon Stack
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 22, p 12443 (2021)
Mesothelin (MSLN), a glycoprotein normally expressed by mesothelial cells, is overexpressed in ovarian cancer (OvCa) suggesting a role in tumor progression, although the biological function is not fully understood. OvCa has a high mortality rate due
Externí odkaz:
https://doaj.org/article/c13afbf1f05f4c64aad9f7c5b4e9fc4f
Autor:
M. Sharon Stack, William J. Kaliney, Toni Page-Mayberry, Siyuan Zhang, Ian Guldner, Elizabeth I. Harper, Jeffery Johnson, Tyvette S. Hilliard, Jing Yang, Yueying Liu, Alejandro Claure De La Zerda, Carlysa Oyama, Allison M. Young, Marwa Asem
Supplementary Data including methods, legends, supplemental figures 1-5 and supplemental table 1-2. Supplemental Fig. 1: WNT5A mRNA and Wnt5a protein expression in OvCa cell lines, Supplemental Fig. 2: Silencing of WNT5A in LP9 human peritoneal mesot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::141ca5f9c12f0622173a0007d3278712
https://doi.org/10.1158/0008-5472.22424355
https://doi.org/10.1158/0008-5472.22424355
Autor:
M. Sharon Stack, William J. Kaliney, Toni Page-Mayberry, Siyuan Zhang, Ian Guldner, Elizabeth I. Harper, Jeffery Johnson, Tyvette S. Hilliard, Jing Yang, Yueying Liu, Alejandro Claure De La Zerda, Carlysa Oyama, Allison M. Young, Marwa Asem
The noncanonical Wnt ligand Wnt5a is found in high concentrations in ascites of women with ovarian cancer. In this study, we elucidated the role of Wnt5a in ovarian cancer metastasis. Wnt5a promoted ovarian tumor cell adhesion to peritoneal mesotheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::479d63d3b82064dec22c82f4609bcce6
https://doi.org/10.1158/0008-5472.c.6511755.v1
https://doi.org/10.1158/0008-5472.c.6511755.v1
Autor:
William Kaliney, Toni M Page-Mayberry, M. Sharon Stack, Ian H. Guldner, Marwa Asem, Carlysa Oyama, Elizabeth I. Harper, Yueying Liu, Allison Young, Siyuan Zhang, Tyvette S. Hilliard, Jing Yang, Alejandro G Claure De La Zerda, Jeffery Johnson
Publikováno v:
Cancer Res
The noncanonical Wnt ligand Wnt5a is found in high concentrations in ascites of women with ovarian cancer. In this study, we elucidated the role of Wnt5a in ovarian cancer metastasis. Wnt5a promoted ovarian tumor cell adhesion to peritoneal mesotheli
Autor:
Tyvette Hilliard, Phillip Petrasko, Yueying Liu, Jing Yang, Marwa Asem, Jeff Johnson, Gifty Marfowaa, Brooke Kowalski, Elinor Schnautz, Morgan McCabe, M. Sharon Stack
Publikováno v:
Cancer Research. 82:2189-2189
Obesity is a worldwide epidemic associated with many cancer types due to persistent inflammation, hyperglycemia and hyperinsulinemia providing an abundance of nutrients and growth factors to cancer cells resulting in an ideal microenvironment. Matern
Autor:
Brian Crowley, Eric Lee, M. Sharon Stack, Elizabeth I. Harper, Norman Jin, Stephen Grisoli, Meghan Conroy, Ashley Klein, Emily Franz, Catlin O'Brien, Chunyan Li, Yueying Liu, Qingfei Wang, Jeffrey J. Johnson, Kelly Volk, Aris T. Alexandrou, Marwa Asem, Annamarie T. Bryant, Siyuan Zhang, Xuejuan Tan, Tyvette S. Hilliard, Katie Santanello, Leigh Campbell, Zonggao Shi, Jing Yang, Anna Grisoli, Annemarie K. Leonard, Connor Ott
Publikováno v:
Cancer Lett
The majority of women with ovarian cancer are diagnosed with metastatic disease, therefore elucidating molecular events that contribute to successful metastatic dissemination may identify additional targets for therapeutic intervention and thereby po
Autor:
Vijayalaxmi Gupta, Alejandro ClaureDeLaZerda, M. Sharon Stack, Yueying Liu, Andrea Jewell, Allison Young, Dineo Khabele, Carlysa Oyama, Matthew J. Ravosa, Marwa Asem
Publikováno v:
Scientific Reports
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
The majority of women with recurrent ovarian cancer (OvCa) develop malignant ascites with volumes that can reach > 2 L. The resulting elevation in intraperitoneal pressure (IPP), from normal values of 5 mmHg to as high as 22 mmHg, causes striking cha
Methods for the visualization and analysis of extracellular matrix protein structure and degradation
Autor:
Marwa Asem, Annemarie K. Leonard, Oleg Kim, M. Sharon Stack, Matthew J. Ravosa, Yueying Liu, Elizabeth Loughran, Kevin R. McAbee, Yuliya Klymenko
This chapter highlights methods for visualization and analysis of extracellular matrix (ECM) proteins, with particular emphasis on collagen type I, the most abundant protein in mammals. Protocols described range from advanced imaging of complex in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77f9bb03f3180e612737f0ea6c04973f
https://doi.org/10.1016/bs.mcb.2017.08.005
https://doi.org/10.1016/bs.mcb.2017.08.005
Autor:
Zonggao Shi, M. Sharon Stack, Marielle Blumenthaler, Tyvette S. Hilliard, Yuliya Klymenko, Jing Yang, Marwa Asem, Yueying Liu, Jeffrey J. Johnson, Annemarie K. Leonard, Elizabeth Loughran, Laura Tarwater, Matthew Leevy, Ryan C. Phan, Matthew J. Ravosa
Publikováno v:
Cancer letters. 411
Ovarian cancer is the fifth leading cause of cancer deaths in U.S. women and the deadliest gynecologic malignancy. This lethality is largely due to the fact that most cases are diagnosed at metastatic stages of the disease when the prognosis is poor.