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pro vyhledávání: '"Marvin S Yu"'
Publikováno v:
SLAS Discov
High-throughput matrix-assisted laser desorption/ionization mass spectrometry (HT-MALDI-MS) has garnered considerable attention within the drug discovery industry as an information-rich alternative to assays using light-based detection methods. To da
Publikováno v:
Journal of Fluorine Chemistry. 130:1042-1048
As ever more protease sequences are uncovered through genome sequencing projects, efficient parallel methods to discover the potential substrates of these proteases becomes crucial. Herein we describe the first use of fluorous-based microarrays to pr
Publikováno v:
Synlett. 2009:554-557
Several aromatic aldehydes are transported by a fluorous amine from one organic phase through a fluorous phase to another organic phase. The derived imines react with phenylhydrazine to immobilize the transported product as a hydrazone and release th
Publikováno v:
Organic Letters. 10:749-752
A fluorous prolinol precatalyst bearing only 34 fluorine atoms has been immobilized in the hydrofluoroether solvent HFE-7500. The CBS reduction of acetophenone proceeded rapidly, in high yield and in high ee in the absence of any organic solvent. The
Publikováno v:
Tetrahedron. 63:9890-9895
Miscibility tests between sixty pairs of fluorous and organic solvents have been performed, and a number of biphasic systems based on hydrofluoroether solvents have been identified. Mutual solubilities of a series of fluorous and organic solvents hav
Publikováno v:
Organic Letters. 7:3677-3680
Low partition coefficients of fluorous components have been a persistent problem in liquid-liquid separations using perfluoroalkanes as the fluorous phase. Solvent tuning of both the nonfluorous and the fluorous phase dramatically enhances the partit
Publikováno v:
Tetrahedron. 54:8355-8370
One- and three-carbon “Dowd-Beckwith” ring expansions of cyclopentanones and cyclohexanones are generally successful, but tandem expansion/cyclization reactions can be compromised by competing processes. An evaluation of the competition between r
Publikováno v:
Synthetic Communications. 26:935-944
The asymmetric synthesis of multi-gram quantities of a pseudomonic acid precursor is described. Improvements on the literature synthesis of diacetyl arabinal from arabinose are also reported.
Autor:
Marvin S, Yu
Publikováno v:
Topics in current chemistry. 308
Fluorous modified reagents and scavengers have been widely used in the synthesis of small molecules and small molecule libraries. This chapter highlights some of those applications based on type of transformation and reagent or scavenger.
Autor:
Marvin S. Yu
Publikováno v:
Topics in Current Chemistry ISBN: 9783642252334
Fluorous modified reagents and scavengers have been widely used in the synthesis of small molecules and small molecule libraries. This chapter highlights some of those applications based on type of transformation and reagent or scavenger.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44f13c19ae105cdf62c34ca04af42b50
https://doi.org/10.1007/128_2011_264
https://doi.org/10.1007/128_2011_264