Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Marvin R. Brown"'
Neuropeptides and Stress presents a comprehensive survey by leading pioneers in the field of the knowledge and concepts implicating neuropeptides in the regulations of responses to stress. Topics covered include: recent advances on the regulation and
Autor:
Terry C. Hammond, Lucinda M. Wead, Gabriela E. Garcia, Margarida M. Mendonca, Marvin R. Brown, Francis B. Gabbai
Publikováno v:
American Journal of Kidney Diseases. 28:115-123
Administration of the nitric oxide (NO) synthase blocker, NG-monomethyl L-arginine prevents the increase in glomerular filtration rate (GFR) normally observed with glycine, an effect that is restored by angiotensin II (All) blockers. These findings s
Publikováno v:
Metabolism. 43:1134-1143
Intracerebroventricular (ICV) injection of carbachol elicits hormonal and metabolic responses similar to moderate stress. In normal dogs, ICV carbachol stimulated marked counterregulatory hormone release, but altered plasma glucose only marginally be
Autor:
Marvin R. Brown, Brian P. Kennedy, Robert J. Parmer, Thai Dinh, Daniel T. O'Connor, Justine H. Cervenka, Marwan A. Takiyyuddin, Sandra D. Braun
Publikováno v:
Journal of Autonomic Pharmacology. 14:187-200
1 In postganglionic sympathetic neurones and adrenal chromaffin cells, catecholamines are co-stored in vesicles with soluble peptides, including chromogranin A (CgA) and neuropeptide Y (NPY), which are subject to exocytotic co-release with catecholam
Autor:
Wylie Vale, R. Galyean, Jean Rivier, Charleen Miller, Catherine Rivier, Gayle Yamamoto, Antonio Miranda, A. G. Craig, Marvin R. Brown
Publikováno v:
Journal of Medicinal Chemistry. 36:2851-2859
In an attempt to determine which conformational parameters are important for the biological activity of ovine corticotropin-releasing factor (oCRF), we have synthesized in significant amounts (50-200 mg) and characterized chemically, structurally (CD
Publikováno v:
Brain Research. 616:283-292
Corticotropin-releasing hormone (CRH) acts at the pituitary level to increase ACTH secretion and, within the central nervous system, to stimulate the sympathoadrenomedullary axis and behavioral activity. In addition, the central administration of CRH
Autor:
Dean A. Kirby, S. C. Koerber, Jean Rivier, A. G. Craig, R. D. Feinstein, L. Delmas, Marvin R. Brown
Publikováno v:
Journal of Medicinal Chemistry. 36:385-393
To further elucidate the minimum bioactive conformation of neuropeptide Y (NPY), a series of truncated and conformationally constrained analogues has been prepared. The synthesis and purification of these peptides was achieved using routine laborator
Autor:
Marvin R. Brown, Laurel A. Fisher
Publikováno v:
Psychotherapy and Psychosomatics. 60:39-45
Peptides are a class of intercellular messengers that are found in virtually every bodily organ. Evidence is reviewed here that peptides may function physiologically in brain pathways that coordinate and integrate whole-organism responses. The focus
Publikováno v:
Journal of Medicinal Chemistry. 35:3653-3659
Truncated, branched, and/or cyclic neuropeptide Y (NPY) analogues were tested for their ability to bind to the neuroblastoma cells, SK-N-MC (Y1 receptor) and SK-N-BE(2) (Y2 receptor). The design of such analogues was inspired by models of NPY based o
Publikováno v:
Endocrinology. 131:1047-1053
CRH acts within the brain to activate the sympathetic nervous system and reduce cellular immune function. To determine the effects of age on CRH-induced elevations of sympathetic activity and suppression of immunity, we examined the responses of plas