Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Marvin O. Boluyt"'
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 300:R993-R1000
The purpose of this study was to test the hypothesis that exercise-induced cardiac adaptations would be attenuated by the free radical scavenger N-2-mercaptopropionyl glycine (MPG). Male Sprague-Dawley rats were divided into four groups ( n = 9–13
Publikováno v:
Medicine & Science in Sports & Exercise. 50:828
Autor:
Bindu Menon, Mahipal Singh, Ekaterina Kaverina, Krishna Singh, Marina Roginskaya, Marvin O. Boluyt, Suman Dalal
Publikováno v:
Cardiovascular Research. 86:20-28
Aims β-Adrenergic receptor (β-AR) stimulation induces apoptosis in adult rat ventricular myocytes (ARVMs) via the activation of glycogen synthase kinase-3β (GSK-3β) and mitochondrial pathways. However, β-AR stimulation induces apoptosis only in
Publikováno v:
ELECTROPHORESIS. 26:3572-3585
Two-dimensional gel electrophoresis (2-DE) is currently the best method for separating complex mixtures of proteins, and its use is gradually becoming more common in cardiac proteome analysis. A number of variations in basic 2-DE have emerged, but th
Autor:
Michael T. Crow, Edward G. Lakatta, Kathleen G. Robinson, Subha Sen, Andrea L. Meredith, Chester H. Conrad, Marvin O. Boluyt, Wesley W. Brooks, O. H. L. Bing
Publikováno v:
American Journal of Hypertension. 18:202-212
Background Pressure overload in humans follows a chronic and progressive course, often resulting in eventual cardiac decompensation and death. Animal models of heart failure generally fail to mimic the temporal features observed in human disease ofte
Autor:
Georgina M. Cirrincione, Marvin O. Boluyt, A F. Scalia, Zhao Bo Li, Amy M. Loyd, Rebecca Jackson
Publikováno v:
Cardiovascular Drugs and Therapy. 18:257-267
Objective: Rapamycin (R) inhibits p70 S6 kinase (p70S6K) activity and hypertrophy of cultured neonatal rat cardiac myocytes. The purpose of the present study was to determine whether rapamycin inhibits left ventricular (L V) hypertrophy in intact rat
Publikováno v:
Heart Failure Reviews. 7:71-88
The spontaneously hypertensive rat (SHR) is an animal model of genetic hypertension which develops heart failure with aging, similar to man. The consistent pattern of a long period of stable hypertrophy followed by a transition to failure provides a
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 281:H581-H589
Myocardial reserve function declines with aging due in part to reduced α- and β-adrenergic receptor (AR)-mediated contractile augmentation. Whereas specific age-associated deficits in β-AR signaling have been identified, it is not known which comp
Autor:
Marvin O. Boluyt, Michael T. Crow, Dennis J. Rozanski, Xilin Long, Edward G. Lakatta, Guimei Wu
Publikováno v:
Heart, Lung and Circulation. 10:121-129
Background: Haem oxygenase (HO-1), a heat shock or stress protein, is a rate-limiting enzyme in the conversion of pro-oxidant haem to biliverdin and carbon monoxide (CO). The products of haem catabolism serve regulatory and protective functions. Prev
Autor:
Wesley W. Brooks, Oscar H. L. Bing, Marvin O. Boluyt, Ashwani Malhotra, James P. Morgan, Naoya Satoh, Wilson S. Colucci, Chester H. Conrad
Publikováno v:
Hypertension. 35:1203-1209
Abstract —Inotropic responsiveness to β-adrenergic stimulation is generally found to be impaired in left ventricular (LV) hypertrophy and failure. To investigate the mechanisms by which angiotensin-converting enzyme inhibitor therapy may modulate