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pro vyhledávání: '"Marurizio Rocchetti"'
Autor:
Margaret Schot, Maria G Zurlo, I.A.M. Mandjes, Marurizio Rocchetti, Jan H.M. Schellens, Hilde Rosing, Koopman Fj, Wim W. ten Bokkel Huinink, Jetske M. Meerum Terwogt, Jos H. Beijnen
Publikováno v:
Anti-cancer drugs. 12(4)
Intravenous administration of paclitaxel is hindered by poor water solubility of the drug. Currently, paclitaxel is dissolved in a mixture of ethanol and Cremophor EL; however, this formulation (Taxol) is associated with significant side effects, whi