Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Marufa, Nasreen"'
Autor:
Ulrike Kappler, Anna Henningham, Marufa Nasreen, Ayaho Yamamoto, Andrew H Buultjens, Timothy P Stinear, Peter Sly, Emmanuelle Fantino
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012282 (2024)
Haemophilus influenzae is a human respiratory pathogen and inhabits the human respiratory tract as its only niche. Despite this, the molecular mechanisms that allow H. influenzae to establish persistent infections of human epithelia are not well unde
Externí odkaz:
https://doaj.org/article/44c07900fcf6437ea3f10fe629ba5f24
Autor:
Marufa Nasreen, Daniel Ellis, Jennifer Hosmer, Ama-Tawiah Essilfie, Emmanuelle Fantino, Peter Sly, Alastair G. McEwan, Ulrike Kappler
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Defenses against oxidative damage to cell components are essential for survival of bacterial pathogens during infection, and here we have uncovered that the DmsABC S-/N-oxide reductase is essential for virulence and in-host survival of the human-adap
Externí odkaz:
https://doaj.org/article/45ee1a4a5cd94359a12b46791327d5f1
Autor:
Jennifer Hosmer, Marufa Nasreen, Rabeb Dhouib, Ama-Tawiah Essilfie, Horst Joachim Schirra, Anna Henningham, Emmanuelle Fantino, Peter Sly, Alastair G McEwan, Ulrike Kappler
Publikováno v:
PLoS Pathogens, Vol 18, Iss 1, p e1010209 (2022)
Haemophilus influenzae (Hi) infections are associated with recurring acute exacerbations of chronic respiratory diseases in children and adults including otitis media, pneumonia, chronic obstructive pulmonary disease and asthma. Here, we show that pe
Externí odkaz:
https://doaj.org/article/05eaa37ec95a40c7bafff26f67c79d27
Autor:
Rabeb Dhouib, Marufa Nasreen, Dk Seti Maimonah Pg Othman, Daniel Ellis, Simon Lee, Ama-Tawiah Essilfie, Philip M. Hansbro, Alastair G. McEwan, Ulrike Kappler
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Although molybdenum-containing enzymes are well-established as having a key role in bacterial respiration, it is increasingly recognized that some may also support bacterial virulence. Here, we show that DmsABC, a putative dimethylsulfoxide (DMSO) re
Externí odkaz:
https://doaj.org/article/4b87150849ab448394b574d939af0c3e
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1557 (2022)
Sulfoxide-damage repair mechanisms are emerging as essential for the virulence of bacterial pathogens, and in the human respiratory pathogen Haemophilus influenzae the periplasmic MsrAB peptide methionine sulfoxide reductase is necessary for resistan
Externí odkaz:
https://doaj.org/article/698a411e58e74cefa634d73df7c667c4
Autor:
Marufa Nasreen, Aidan Fletcher, Jennifer Hosmer, Qifeng Zhong, Ama-Tawiah Essilfie, Alastair G. McEwan, Ulrike Kappler
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Extracytoplasmic function (ECF) sigma factors underpin the ability of bacteria to adapt to changing environmental conditions, a process that is particularly relevant in human pathogens that inhabit niches where human immune cells contribute to high l
Externí odkaz:
https://doaj.org/article/ea672215f966452396ba651d737fe55a
Autor:
Yi Jie Chelsea Tan, Chengzhi Zhao, Marufa Nasreen, Leo O’Rourke, Rabeb Dhouib, Leah Roberts, Ying Wan, Scott A. Beatson, Ulrike Kappler
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Although sulfite, a by-product of the degradation of many sulfur compounds, is highly reactive and can cause damage to DNA, proteins and lipids, comparatively little is known about the regulation of sulfite-oxidizing enzyme (SOEs) expression. Here we
Externí odkaz:
https://doaj.org/article/72f39af1fce2422095ef9a2b2e8ee371
Autor:
Rabeb Dhouib, Dk Seti Maimonah Pg Othman, Victor Lin, Xuanjie Jason Lai, Hewa Godage Sithija Wijesinghe, Ama-Tawiah Essilfie, Amanda Davis, Marufa Nasreen, Paul V Bernhardt, Philip Michael Hansbro, Alastair G McEwan, Ulrike Kappler
Publikováno v:
Frontiers in Microbiology, Vol 7 (2016)
H. influenzae is a host adapted human mucosal pathogen involved in a variety of acute and chronic respiratory tract infections, including Chronic Obstructive Pulmonary Disease (COPD) and asthma, all of which rely on ability to efficiently establish c
Externí odkaz:
https://doaj.org/article/600a4efd0cf343019a94bcab054af688
Autor:
Jennifer Hosmer, Manish Mahawar, Rabeb Dhouib, Patrick J. Blackall, Ama-Tawiah Essilfie, Hewa G. S. Wijesinghe, Alastair G. McEwan, Ulrike Kappler, Marufa Nasreen, Aidan Fletcher
Publikováno v:
ACS Infectious Diseases. 6:1928-1939
Peptide methionine sulfoxide reductases (Msrs) are enzymes that repair ROS-damage to sulfur-containing amino acids such as methionine, ensuring functional integrity of cellular proteins. Here we have shown that unlike the majority of pro- and eukaryo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::878004de5f697b5525081bcf16375252
https://doi.org/10.1021/acsinfecdis.0c00242
https://doi.org/10.1021/acsinfecdis.0c00242
Autor:
Alastair G. McEwan, Rabeb Dhouib, Ama-Tawiah Essilfie, Ulrike Kappler, Daniel Ellis, Dk Seti Maimonah Pg Othman, Simon Lee, Philip M. Hansbro, Marufa Nasreen
Publikováno v:
Frontiers in Microbiology
Frontiers in Microbiology, Vol 12 (2021)
Frontiers in Microbiology, Vol 12 (2021)
Although molybdenum-containing enzymes are well-established as having a key role in bacterial respiration, it is increasingly recognized that some may also support bacterial virulence. Here, we show that DmsABC, a putative dimethylsulfoxide (DMSO) re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dbd475abbe53e6a7647ad39728e981a
http://europepmc.org/articles/PMC8340005
http://europepmc.org/articles/PMC8340005