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pro vyhledávání: '"Maruan Higazi-Vega"'
Autor:
Giulia Fabbri, Jordi Bertran-Alamillo, David Britton, Shona Ellison, Jon Travers, Urszula M. Polanska, Ana Giménez-Capitán, Vinothini Rajeeve, Jelena Urosevic, Pedro Rodriguez-Cutillas, Arran Dokal, Miguel Angel Molina-Vila, Maruan Higazi-Vega, Edmund Wilkes, J. Elizabeth Pease, Ruth Osuntola, Calum Greenhalgh, Hilary J. Lewis
Publikováno v:
Cancer Research. 81:1107-1107
Background: NSCLC cells carrying EGFR mutations can gain resistance to cognate TKIs through amplification of Chr22q11.2 (Chr22amp), a chromosome segment containing CRKL. This also specifically associates with exquisite sensitivity to inhibitors of Au