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Publikováno v:
Molecules, Vol 22, Iss 5, p 827 (2017)
Despite the great contribution of natural products in the history of successful drug discovery, there are significant limitations that persuade the pharmaceutical industry to evade natural products in drug discovery research. The extreme scarcity as
Externí odkaz:
https://doaj.org/article/cc64cdedfa1a4016af781fe562dd55e9
Publikováno v:
Molecules; Volume 22; Issue 5; Pages: 827
Molecules, Vol 22, Iss 5, p 827 (2017)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Molecules, Vol 22, Iss 5, p 827 (2017)
Molecules : A Journal of Synthetic Chemistry and Natural Product Chemistry
Despite the great contribution of natural products in the history of successful drug discovery, there are significant limitations that persuade the pharmaceutical industry to evade natural products in drug discovery research. The extreme scarcity as
Autor:
Paola Fossa, Fabrizio Giordanetto, Olga Bruno, Sara Guariento, Xenia Iwanowa, Gessica Marchini, Anna Karawajczyk, James A. Bull, Martyna Bielska
Phosphodiesterase 4 (PDE4) inhibitors have attractive therapeutic potential in respiratory, inflammatory, metabolic and CNS disorders. The present work details the design, chemical exploration and biological profile of a novel PDE4 inhibitor chemotyp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2be80e083fd910e25894f1f89559556
http://hdl.handle.net/11567/859080
http://hdl.handle.net/11567/859080