Zobrazeno 1 - 10
of 98
pro vyhledávání: '"Martyn P Mahaut-Smith"'
Autor:
Joy R Wright, Sarah Jones, Sasikumar Parvathy, Leonard K Kaczmarek, Ian Forsythe, Richard W Farndale, Jonathan M Gibbins, Martyn P Mahaut-Smith
Publikováno v:
Platelets, Vol 33, Iss 3 (2022)
Kv1.3 is a voltage-gated K+-selective channel with roles in immunity, insulin-sensitivity, neuronal excitability and olfaction. Despite being one of the largest ionic conductances of the platelet surface membrane, its contribution to platelet functio
Externí odkaz:
https://doaj.org/article/ebc5c55ad75949f58bc9d3e1e51b0f27
Autor:
Danijela Markovic, Jonathan Holdich, Suleiman Al-Sabah, Rajendra Mistry, Cornelius Krasel, Martyn P Mahaut-Smith, R A John Challiss
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29946 (2012)
Muscarinic acetylcholine receptors (mAChRs) are 7-transmembrane, G protein-coupled receptors that regulate a variety of physiological processes and represent potentially important targets for therapeutic intervention. mAChRs can be stimulated by full
Externí odkaz:
https://doaj.org/article/6f2ae794a82940a8b0a3ea346afcd0b3
Autor:
Martyn P. Mahaut-Smith, Joy R. Wright
Publikováno v:
Platelets. 32:872-879
Potassium ions have widespread roles in cellular homeostasis and activation as a consequence of their large outward concentration gradient across the surface membrane and ability to rapidly move through K+-selective ion channels. In platelets, the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd0e93ef426df056d3b352781d5055b2
https://doi.org/10.1080/09537104.2021.1904135
https://doi.org/10.1080/09537104.2021.1904135
Autor:
Martyn P. Mahaut-Smith, Kirk A. Taylor
Publikováno v:
Platelets. 32(7)
The lipid bilayer of surface and organellar cell membranes represents a barrier to simple diffusion of inorganic ions or other charged molecules between extracellular and intracellular fluid compar...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e79aad1cdf8f3391c867e668386cebff
https://pubmed.ncbi.nlm.nih.gov/34370618
https://pubmed.ncbi.nlm.nih.gov/34370618
Autor:
Joy R, Wright, Sarah, Jones, Sasikumar, Parvathy, Leonard K, Kaczmarek, Ian, Forsythe, Richard W, Farndale, Jonathan M, Gibbins, Martyn P, Mahaut-Smith
Publikováno v:
Platelets. 33(3)
Kv1.3 is a voltage-gated K
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e664ead5ec21dde82d1afa4a8f406b49
https://pubmed.ncbi.nlm.nih.gov/34348571
https://pubmed.ncbi.nlm.nih.gov/34348571
Publikováno v:
Purinergic Signalling
A P2X1-eYFP knock-in mouse was generated to study receptor expression and mobility in smooth muscle and blood cells. eYFP was added to the C-terminus of the P2X1R and replaced the native P2X1R. Fluorescence corresponding to P2X1-eYFPR was detected in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e560ca56a833b54632f1b1ecd6ad5a8a
https://doi.org/10.1007/s11302-019-09666-1
https://doi.org/10.1007/s11302-019-09666-1
Autor:
Martyn P. Mahaut-Smith, Kirk A. Taylor
Publikováno v:
Platelets
TMEM16F is a surface membrane protein critical for platelet procoagulant activity, which exhibits both phospholipid scramblase and ion channel activities following sustained elevation of cytosolic Ca2+. The extent to which the ionic permeability of T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d3f1183d87fa7c7d4c2b85eb45de541
https://doi.org/10.1080/09537104.2019.1595560
https://doi.org/10.1080/09537104.2019.1595560
Autor:
Joy R, Wright, Martyn P, Mahaut-Smith
Publikováno v:
Platelets
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Potassium ions have widespread roles in cellular homeostasis and activation as a consequence of their large outward concentration gradient across the surface membrane and ability to rapidly move through K+-selective ion channels. In platelets, the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6162503a7e3411bb5552099baf99a4a3
https://pubmed.ncbi.nlm.nih.gov/33872124
https://pubmed.ncbi.nlm.nih.gov/33872124
Publikováno v:
Science signaling. 13(615)
Cells sense extracellular nucleotides through the P2Y class of purinergic G protein-coupled receptors (GPCRs), which stimulate integrin activation through signaling events, including intracellular Ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0d6671d38495476e3bd4e37a685be65
https://pubmed.ncbi.nlm.nih.gov/31964805
https://pubmed.ncbi.nlm.nih.gov/31964805
Publikováno v:
Science Signaling. 13
Cells sense extracellular nucleotides through the P2Y class of purinergic G protein-coupled receptors (GPCRs), which stimulate integrin activation through signaling events, including intracellular Ca2+ mobilization. We investigated the relationship b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e6ada4e993705cad41db933366de74cb
https://doi.org/10.1126/scisignal.aav7354
https://doi.org/10.1126/scisignal.aav7354