Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Martyn L Foster"'
Autor:
Fernando M Botelho, Carla M T Bauer, Donna Finch, Jake K Nikota, Caleb C J Zavitz, Ashling Kelly, Kristen N Lambert, Sian Piper, Martyn L Foster, James J P Goldring, Jadwiga A Wedzicha, Jennifer Bassett, Jonathan Bramson, Yoichiro Iwakura, Matthew Sleeman, Roland Kolbeck, Anthony J Coyle, Alison A Humbles, Martin R Stämpfli
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e28457 (2011)
Cigarette smoking is the main risk factor for the development of chronic obstructive pulmonary disease (COPD), a major cause of morbidity and mortality worldwide. Despite this, the cellular and molecular mechanisms that contribute to COPD pathogenesi
Externí odkaz:
https://doaj.org/article/a66704c4920d4a94bf3ed0aae0e515f7
Autor:
Georgios Divolis, Evgenia Synolaki, Athanasia Doulou, Ariana Gavriil, Christina C. Giannouli, Anastasia Apostolidou, Martyn L. Foster, Martin M. Matzuk, Panagiotis Skendros, Ioanna-Evdokia Galani, Paschalis Sideras
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundPre-neutrophils, while developing in the bone marrow, transcribe the Inhba gene and synthesize Activin-A protein, which they store and release at the earliest stage of their activation in the periphery. However, the role of neutrophil-deriv
Externí odkaz:
https://doaj.org/article/cb18a5bdb9a14639863030d911714e67
Autor:
Gabriele Matschiner, Mary F. Fitzgerald, Ulrich Moebius, Andreas M. Hohlbaum, Hendrik Gille, Kristian Jensen, Klaus Kirchfeld, Barbara Rattenstetter, Alice Laforge, Rachida S. Bel Aiba, Joe Ciccotosto, Hong Nyugen, Martyn L. Foster, John N. Snouwaert, MyTrang Nguyen, Beverly H. Koller, Louis Matis, Gary P. Anderson, Shane A. Olwill
Publikováno v:
The Journal of allergy and clinical immunology.
T2 endotype asthma is driven by IL-4 and IL-13 signaling via IL-4Ra, which is highly expressed on airway epithelium, airway smooth muscle and immunocytes in the respiratory mucosa, suggesting potential advantages of an inhalable antagonist. Lipocalin
Autor:
Martyn L. Foster
Publikováno v:
Current Opinion in Toxicology. 3:48-54
• Reasons for failure of pre-clinical disease models to predict clinical efficacy are complex.