Phage-Displayed SH2 Domain Libraries: From Ultrasensitive Tyrosine Phosphoproteome Probes to Translational Research.

Autor: Martyn GD; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Veggiani G; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, Ontario M5S 3E1, Canada gveggiani@lsu.edu.; Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, Louisiana 70803, USA.

Publikováno v: Cold Spring Harbor protocols [Cold Spring Harb Protoc] 2024 May 02; Vol. 2024 (5), pp. 107981. Date of Electronic Publication: 2024 May 02.

Author Correction: High-affinity chromodomains engineered for improved detection of histone methylation and enhanced CRISPR-based gene repression.

Autor: Veggiani G; The Anvil Institute, Kitchener, ON, N2G 1H6, Canada. gveggiani@lsu.edu.; Department of Pathobiological Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, 70803, USA. gveggiani@lsu.edu., Villaseñor R; Division of Molecular Biology, Biomedical Center Munich, Ludwig-Maximilians-University, 82152, Planegg-Martinsried, Germany.; Department of Molecular Mechanisms of Disease, University of Zurich, 8057, Zurich, Switzerland., Martyn GD; The Anvil Institute, Kitchener, ON, N2G 1H6, Canada.; School of Pharmacy, University of Waterloo, Waterloo, ON, N2L 3G1, Canada., Tang JQ; The Anvil Institute, Kitchener, ON, N2G 1H6, Canada.; School of Pharmacy, University of Waterloo, Waterloo, ON, N2L 3G1, Canada., Krone MW; Department of Chemistry, University of North Carolina at Chapel Hill, CB 3290, Chapel Hill, NC, 27599, USA., Gu J; The Anvil Institute, Kitchener, ON, N2G 1H6, Canada., Chen C; The Anvil Institute, Kitchener, ON, N2G 1H6, Canada., Waters ML; Department of Chemistry, University of North Carolina at Chapel Hill, CB 3290, Chapel Hill, NC, 27599, USA., Pearce KH; Center for Integrative Chemical Biology and Drug Discovery, Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA., Baubec T; Department of Molecular Mechanisms of Disease, University of Zurich, 8057, Zurich, Switzerland.; Division of Genome Biology and Epigenetics, Institute of Biodynamics and Biocomplexity, Department of Biology, Utrecht University, 3584, Utrecht, The Netherlands., Sidhu SS; The Anvil Institute, Kitchener, ON, N2G 1H6, Canada. sachdev.sidhu@uwaterloo.ca.; School of Pharmacy, University of Waterloo, Waterloo, ON, N2L 3G1, Canada. sachdev.sidhu@uwaterloo.ca.

Publikováno v: Nature communications [Nat Commun] 2022 Nov 30; Vol. 13 (1), pp. 7381. Date of Electronic Publication: 2022 Nov 30.

Engineered SH2 Domains for Targeted Phosphoproteomics.

Autor: Martyn GD; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S3E1, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada., Veggiani G; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S3E1, Canada., Kusebauch U; Institute for Systems Biology, Seattle, Washington 98109, United States., Morrone SR; Institute for Systems Biology, Seattle, Washington 98109, United States., Yates BP; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S3E1, Canada., Singer AU; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S3E1, Canada., Tong J; Program in Cell biology, Hospital for Sick Children, Toronto M5G 0A4, Canada., Manczyk N; Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada.; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada., Gish G; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada., Sun Z; Institute for Systems Biology, Seattle, Washington 98109, United States., Kurinov I; Department of Chemistry and Chemical Biology, Cornell University, NE-CAT, Argonne, Illinois 60439, United States., Sicheri F; Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.; Department of Biochemistry, University of Toronto, Toronto, Ontario M5S 1A8, Canada.; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada., Moran MF; Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.; Program in Cell biology, Hospital for Sick Children, Toronto M5G 0A4, Canada.; The Hospital for Sick Children, SPARC Biocentre, Toronto, Ontario M5G 0A4, Canada., Moritz RL; Institute for Systems Biology, Seattle, Washington 98109, United States., Sidhu SS; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, 160 College Street, Toronto, Ontario M5S3E1, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5S 1A8, Canada.

Publikováno v: ACS chemical biology [ACS Chem Biol] 2022 Jun 17; Vol. 17 (6), pp. 1472-1484. Date of Electronic Publication: 2022 May 25.

Protein-phosphotyrosine proteome profiling by superbinder-SH2 domain affinity purification mass spectrometry, sSH2-AP-MS.

Autor: Tong J; Program in Cell Biology, Hospital for Sick Children, Toronto, Canada., Cao B; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, P. R. China., Martyn GD; Department of Molecular Genetics, University of Toronto, Toronto, Canada., Krieger JR; SPARC BioCentre, Hospital for Sick Children, Toronto, Canada., Taylor P; Program in Cell Biology, Hospital for Sick Children, Toronto, Canada.; SPARC BioCentre, Hospital for Sick Children, Toronto, Canada., Yates B; Department of Molecular Genetics, University of Toronto, Toronto, Canada.; Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, Toronto, Canada., Sidhu SS; Department of Molecular Genetics, University of Toronto, Toronto, Canada.; Banting and Best Department of Medical Research, Donnelly Centre, University of Toronto, Toronto, Canada., Li SS; Department of Biochemistry and Siebens-Drake Medical Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Canada., Mao X; Department of Pharmacology, College of Pharmaceutical Sciences, Soochow University, Suzhou, P. R. China., Moran MF; Program in Cell Biology, Hospital for Sick Children, Toronto, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Canada.

Publikováno v: Proteomics [Proteomics] 2017 Mar; Vol. 17 (6). Date of Electronic Publication: 2017 Jan 17.

Alternative oxidase: a respiratory electron transport chain pathway essential for maintaining photosynthetic performance during drought stress.

Autor: Vanlerberghe GC; Department of Biological Sciences, University of Toronto Scarborough, Toronto, ON, M1C1A4, Canada.; Department of Cell and Systems Biology, University of Toronto Scarborough, Toronto, ON, M1C1A4, Canada., Martyn GD; Department of Biological Sciences, University of Toronto Scarborough, Toronto, ON, M1C1A4, Canada.; Department of Cell and Systems Biology, University of Toronto Scarborough, Toronto, ON, M1C1A4, Canada., Dahal K; Department of Biological Sciences, University of Toronto Scarborough, Toronto, ON, M1C1A4, Canada.; Department of Cell and Systems Biology, University of Toronto Scarborough, Toronto, ON, M1C1A4, Canada.

Publikováno v: Physiologia plantarum [Physiol Plant] 2016 Jul; Vol. 157 (3), pp. 322-37. Date of Electronic Publication: 2016 May 24.