Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Marty G, Yang"'
Publikováno v:
eLife, Vol 11 (2022)
Sequence variation in enhancers that control cell-type-specific gene transcription contributes significantly to phenotypic variation within human populations. However, it remains difficult to predict precisely the effect of any given sequence variant
Externí odkaz:
https://doaj.org/article/637ec108529642a3a214676a933beab7
Autor:
Liang-Fu Chen, Yen Ting Lin, David A. Gallegos, Mariah F. Hazlett, Mariana Gómez-Schiavon, Marty G. Yang, Breanna Kalmeta, Allen S. Zhou, Liad Holtzman, Charles A. Gersbach, Jörg Grandl, Nicolas E. Buchler, Anne E. West
Publikováno v:
Cell Reports, Vol 26, Iss 5, Pp 1174-1188.e5 (2019)
Summary: Neuronal activity-inducible gene transcription correlates with rapid and transient increases in histone acetylation at promoters and enhancers of activity-regulated genes. Exactly how histone acetylation modulates transcription of these gene
Externí odkaz:
https://doaj.org/article/abdd1b6312db4a65935613e4d4bd4d8e
Publikováno v:
eLife. 11
Sequence variation in enhancers that control cell-type-specific gene transcription contributes significantly to phenotypic variation within human populations. However, it remains difficult to predict precisely the effect of any given sequence variant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6f2c026cfb5b71f1e8a21ec2746175
https://doi.org/10.7554/elife.76500
https://doi.org/10.7554/elife.76500
Autor:
Eric C. Griffith, Jesse M. Engreitz, Gabriella L. Boulting, Michael R. Blanchard, Daniel Hochbaum, Ava C. Carter, David A. Harmin, Michael E. Greenberg, Maxwell A. Sherman, Adam J. Granger, Kevin Mei, Sinisa Hrvatin, Bulent Ataman, Marty G. Yang, Ershela Durresi
Publikováno v:
Nature neuroscience
Neuronal activity-dependent gene expression is essential for brain development. Although transcriptional and epigenetic effects of neuronal activity have been explored in mice, such an investigation is lacking in humans. Because alterations in GABAer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a768f66e9dda312e76589792c9a152b
https://doi.org/10.1038/s41593-020-00786-1
https://doi.org/10.1038/s41593-020-00786-1
Autor:
Marty G. Yang, Andrew E. Timms, Timothy J. Cherry, David A. Harmin, Rui Chen, Peter Tao, Miriam Bauwens, Elfride De Baere, Rando Allikmets, Michael E. Greenberg, Evan M Jones
Publikováno v:
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
The interplay of transcription factors and cis -regulatory elements (CREs) orchestrates the dynamic and diverse genetic programs that assemble the human central nervous system (CNS) during development and maintain its function throughout life. Geneti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfa2d43f9adb715fbe49b9f78ea9c9d2
https://doi.org/10.1073/pnas.1922501117
https://doi.org/10.1073/pnas.1922501117
Autor:
Timothy J, Cherry, Marty G, Yang, David A, Harmin, Peter, Tao, Andrew E, Timms, Miriam, Bauwens, Rando, Allikmets, Evan M, Jones, Rui, Chen, Elfride, De Baere, Michael E, Greenberg
Publikováno v:
Proc Natl Acad Sci U S A
The interplay of transcription factors and cis-regulatory elements (CREs) orchestrates the dynamic and diverse genetic programs that assemble the human central nervous system (CNS) during development and maintain its function throughout life. Genetic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f307a00d0b450214a19395d81039987
https://pubmed.ncbi.nlm.nih.gov/32265282
https://pubmed.ncbi.nlm.nih.gov/32265282
Autor:
Benyam Kinde, Alexander W. Greben, Emmy Li, Hume Stroud, Andrew Silberfeld, Lisa D. Boxer, Tess Whitwam, Eric C. Griffith, Boyan B. Bonev, Michael E. Greenberg, Marty G. Yang, William Renthal
Publikováno v:
Mol. Cell 77, 294-309.e9 (2020)
Mol Cell
Mol Cell
Mutations in the methyl-DNA-binding repressor protein MeCP2 cause the devastating neurodevelopmental disorder Rett syndrome. It has been challenging to understand how MeCP2 regulates transcription because MeCP2 binds broadly across the genome, and Me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3274932aec2be562569c83f8776db003
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=57858
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=57858
Autor:
Hume Stroud, Yael N. Tsitohay, Maxwell A. Sherman, Christopher P. Davis, Michael E. Greenberg, Sinisa Hrvatin, Emi Ling, Marty G. Yang
Publikováno v:
Neuron
The maturation of the mammalian brain occurs after birth, and this stage of neuronal development is frequently impaired in neurological disorders such as autism and schizophrenia. However, the mechanisms that regulate postnatal brain maturation are p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::673c8a3848924028283524764a77b201
https://pubmed.ncbi.nlm.nih.gov/32678311
https://pubmed.ncbi.nlm.nih.gov/32678311
Autor:
Peter Tao, Evan M. Jones, David A. Harmin, Rui Chen, Rando Allikmets, Michael E. Greenberg, Marty G. Yang, Timothy J. Cherry, Miriam Bauwens, Andrew E. Timms, Elfride De Baere
Cis-regulatory elements (CREs) orchestrate the dynamic and diverse transcriptional programs that assemble the human central nervous system (CNS) during development and maintain its function throughout life. Genetic variation within CREs plays a centr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74dc4f280982cae6b2e272e64566b81b