Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Martti Tolvanen"'
Autor:
Susanna Haapanen, Andrea Angeli, Martti Tolvanen, Reza Zolfaghari Emameh, Claudiu T. Supuran, Seppo Parkkila
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 38, Iss 1 (2023)
Schistosoma mansoni is an intestinal parasite with one β-class carbonic anhydrase, SmaBCA. We report the sequence enhancing, production, catalytic activity, and inhibition results of the recombinant SmaBCA. It showed significant catalytic activity o
Externí odkaz:
https://doaj.org/article/3790dc0dd24242b7a7f439f695ddde5a
Autor:
Ashok Aspatwar, Harlan Barker, Heidi Aisala, Ksenia Zueva, Marianne Kuuslahti, Martti Tolvanen, Craig R. Primmer, Jaakko Lumme, Alessandro Bonardi, Amit Tripathi, Seppo Parkkila, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 37, Iss 1, Pp 1577-1586 (2022)
A β-class carbonic anhydrase (CA, EC 4.2.1.1) was cloned from the genome of the Monogenean platyhelminth Gyrodactylus salaris, a parasite of Atlantic salmon. The new enzyme, GsaCAβ has a significant catalytic activity for the physiological reaction
Externí odkaz:
https://doaj.org/article/bdf016d9e23e49eba9c8db7310530d47
Autor:
Kai, Hakala, Suwisa, Kaewphan, Jari, Bjorne, Farrokh, Mehryary, Hans, Moen, Martti, Tolvanen, Tapio, Salakoski, Filip, Ginter
Publikováno v:
IEEE/ACM transactions on computational biology and bioinformatics. 19(3)
Over the past decade, the demand for automated protein function prediction has increased due to the volume of newly sequenced proteins. In this paper, we address the function prediction task by developing an ensemble system automatically assigning Ge
Protein-protein communications govern cellular processes via complex regulatory networks, that are still far from being understood. Thus, identifying novel interactions between proteins can significantly facilitate our comprehension of the mechanisti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::702184516e56f2bd80a8073cfd495a72
https://doi.org/10.1101/2020.09.29.315374
https://doi.org/10.1101/2020.09.29.315374
Transcription factor (TF) proteins play a critical role in the regulation of eukaryote gene expression by sequence-specific binding to genomic locations known as transcription factor binding sites.Here we present the TFBSFootprinter tool which has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58001d6b0722e6fb22787287057a0bf6
https://doi.org/10.1101/2020.09.04.282749
https://doi.org/10.1101/2020.09.04.282749
Autor:
Heini Kallio, Martti Tolvanen, Janne Jänis, Pei-wen Pan, Eeva Laurila, Anne Kallioniemi, Sami Kilpinen, Vilppu J Tuominen, Jorma Isola, Jarkko Valjakka, Silvia Pastorekova, Jaromir Pastorek, Seppo Parkkila
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27152 (2011)
Our previous microarray study showed that the non-specific cytotoxic cell receptor protein 1 (Nccrp1) transcript is significantly upregulated in the gastric mucosa of carbonic anhydrase IX (CA IX)-deficient (Car9(-/-)) mice. In this paper, we aimed t
Externí odkaz:
https://doaj.org/article/bae20915bfed4d848993aed335d49468
Autor:
Jari Björne, Suwisa Kaewphan, Martti Tolvanen, Tapio Salakoski, Hans Moen, Filip Ginter, Farrokh Mehryary, Kai Hakala
Over the past decade, the demand for automated protein function prediction has increased due to the volume of newly sequenced proteins. In this paper, we address the function prediction task by developing an ensemble system automatically assigning Ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::664626b9707d778625bb59ba6f1947af
Autor:
Renzhi Cao, Alice C. McHardy, Cen Wan, Jonathan G. Lees, Vedrana Vidulin, Alex Warwick Vesztrocy, Huy N Nguyen, Devon Johnson, Ian Sillitoe, Alessandro Petrini, Richard Bonneau, Hans Moen, Peter L. Freddolino, Rui Fa, Alfredo Benso, Jianlin Cheng, Indika Kahanda, Qizhong Mao, Zihan Zhang, Chenguang Zhao, Rebecca L. Hurto, Predrag Radivojac, Stefano Di Carlo, Sayoni Das, Suwisa Kaewphan, Sabeur Aridhi, Alan Medlar, Casey S. Greene, Constance J. Jeffery, Christophe Dessimoz, Jose Manuel Rodriguez, Gianfranco Politano, Michele Berselli, Jia-Ming Chang, Deborah A. Hogan, Julian Gough, Tunca Doğan, David T. Jones, Claire O'Donovan, Volkan Atalay, Paolo Fontana, Feng Zhang, Shuwei Yao, Robert Hoehndorf, Olivier Lichtarge, Alex W. Crocker, Ahmet Sureyya Rifaioglu, Rabie Saidi, Farrokh Mehryary, Neven Sumonja, Yang Zhang, Florian Boecker, Jie Hou, Christine A. Orengo, Matteo Re, Natalie Thurlby, Chengxin Zhang, Stefano Pascarelli, Alberto Paccanaro, Hafeez Ur Rehman, Yuxiang Jiang, Mohammad R. K. Mofrad, Naihui Zhou, Asa Ben-Hur, Steven E. Brenner, Martti Tolvanen, Filip Ginter, Mark N. Wass, Patricia C. Babbitt, David W. Ritchie, George Georghiou, Stefano Toppo, Caleb Chandler, Larry Davis, Da Chen Emily Koo, Itamar Borukhov, Petri Törönen, Rengul Cetin-Atalay, Fabio Fabris, Haixuan Yang, Kai Hakala, Silvio C. E. Tosatto, Domenico Cozzetto, Slobodan Vucetic, Balint Z. Kacsoh, Luke W Sagers, Alex A. Freitas, Tapio Salakoski, Fran Supek, Alfonso E. Romero, Angela D. Wilkins, Elaine Zosa, Shanshan Zhang, Yotam Frank, Jonathan B. Dayton, Jeffrey M. Yunes, Pier Luigi Martelli, Dallas J. Larsen, Giuliano Grossi, Alexandra J. Lee, Marco Mesiti, Yi-Wei Liu, Jonas Reeb, Damiano Piovesan, Sean D. Mooney, Magdalena Antczak, Erica Suh, Marco Falda, Marie-Dominique Devignes, Castrense Savojardo, Zheng Wang, Danielle A Brackenridge, Peter W. Rose, Enrico Lavezzo, Dane Jo, Ronghui You, Tomislav Šmuc, Liam J. McGuffin, Michael L. Tress, Ilya Novikov, Adrian M. Altenhoff, Burkhard Rost, Miguel Amezola, Mateo Torres, Prajwal Bhat, Wen-Hung Liao, Meet Barot, Marco Notaro, Suyang Dai, Giorgio Valentini, Jari Björne, Nevena Veljkovic, Wei-Cheng Tseng, Po-Han Chi, Alperen Dalkiran, Maxat Kulmanov, Nafiz Hamid, Aashish Jain, Branislava Gemovic, Alexandre Renaux, Ashton Omdahl, Daniel B. Roche, Vladimir Perovic, Iddo Friedberg, Daisuke Kihara, Giovanni Bosco, Gage S. Black, Saso Dzeroski, Liisa Holm, Marco Frasca, Michal Linial, Ehsaneddin Asgari, Tatyana Goldberg, Maria Jesus Martin, Vladimir Gligorijević, Marco Carraro, Shanfeng Zhu, Radoslav Davidovic, Timothy Bergquist, Hai Fang, José M. Fernández, Giuseppe Profiti, Weidong Tian, Imane Boudellioua, Kimberley A. Lewis, Seyed Ziaeddin Alborzi, Rita Casadio
The Critical Assessment of Functional Annotation (CAFA) is an ongoing, global, community-driven effort to evaluate and improve the computational annotation of protein function. Here we report on the results of the third CAFA challenge, CAFA3, that fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4041959032930476de14481a887bcd78
Protozoan pathogens are major contributors to illness and death globally. Much of their impact can be controlled by a few drugs that are available. The resistance of these organisms to the existing drugs has threatened the treatment options. Therefor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f40e66e1444d11a526fd68d4d6097107
https://doi.org/10.1016/b978-0-12-816476-1.00020-4
https://doi.org/10.1016/b978-0-12-816476-1.00020-4
Autor:
Vincenzo Alterio, Andrea Angeli, Ashok Aspatwar, Joelle Ayoub, Mihail Barboiu, Harlan Barker, Emanuela Berrino, Patrizio Blandina, Alessandro Bonardi, Murat Bozdag, Silvia Bua, Martina Buonanno, Clemente Capasso, Simone Carradori, Fabrizio Carta, Katia D'Ambrosio, Giuseppina De Simone, Anna Di Fiore, William A. Donald, Reza Zolfaghari Emameh, Davide Esposito, Marta Ferraroni, Paola Gratteri, Paolo Guglielmi, Marc A. Ilies, Emma Langella, Laura Lucarini, Emanuela Masini, Robert McKenna, Simona Maria Monti, Akilah B. Murray, Alessio Nocentini, Seppo Parkkila, Andrea Scozzafava, Silvia Sgambellone, Claudiu T. Supuran, Muhammet Tanc, Martti Tolvanen, Daniela Vullo, Jean-Yves Winum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f517e5aa3672a2b5ac8b0f0a898b1e8
https://doi.org/10.1016/b978-0-12-816476-1.01002-9
https://doi.org/10.1016/b978-0-12-816476-1.01002-9