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First-line osimertinib in patients with epidermal growth factor receptor-mutant non-small-cell lung cancer and with a coexisting low allelic fraction of Thr790Met

Autor: Majem, M, Sullivan, I, Viteri, S, Lopez-Vivanco, G, Cobo, M, Sanchez, JM, Garcia-Gonzalez, J, Garde, J, Sampayo, M, Martrat, G, Malfettone, A, Karachaliou, N, Molina-Vila, MA, Rosell, R

Publikováno v: EUROPEAN JOURNAL OF CANCER
r-FISABIO. Repositorio Institucional de Producción Científica
instname
European Journal of Cancer
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau

Aim of the study: The AZENT (NCT02841579) study aimed to assess the efficacy and safety of first-line osimertinib in patients with epidermal growth factor receptor(EGFR) mutation-positive advanced non-small-cell lung cancer (NSCLC) and with a coexist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0d5cc9b707e8f28dd4356b087e9b25ac
https://fundanet.fisabio.san.gva.es/publicaciones/ProdCientif/PublicacionFrw.aspx?id=12661

Interplay between BRCA1 and RHAMM Regulates Epithelial Apicobasal Polarization and May Influence Risk of Breast Cancer

Autor: Maxwell, C.A., Benitez, J., Gomez-Baldo, L., Osorio, A., Bonifaci, N., Fernandez-Ramires, R., Costes, S.V., Guino, E., Chen, H., Evans, G.J., Mohan, P., Catala, I., Petit, A., Aguilar, H., Villanueva, A., Aytes, A., Serra-Musach, J., Rennert, G., Lejbkowicz, F., Peterlongo, P., Manoukian, S., Peissel, B., Ripamonti, C.B., Bonanni, B., Viel, A., Allavena, A., Bernard, L., Radice, P., Friedman, E., Kaufman, B., Laitman, Y., Dubrovsky, M., Milgrom, R., Jakubowska, A., Cybulski, C., Gorski, B., Jaworska, K., Durda, K., Sukiennicki, G., Lubinski, J., Shugart, Y.Y., Domchek, S.M., Letrero, R., Weber, B.L., Hogervorst, F.B.L., Rookus, M.A., Collee, J.M., Devilee, P., Ligtenberg, M.J.L., Luijt, R.B. van der, Aalfs, C.M., Waisfisz, Q., Wijnen, J., Roozendaal, C.E.P. van, Easton, D.F., Peock, S., Cook, M., Oliver, C., Frost, D., Harrington, P., Evans, D.G., Lalloo, F., Eeles, R., Izatt, L., Chu, C., Eccles, D., Douglas, F., Brewer, C., Nevanlinna, H., Heikkinen, T., Couch, F.J., Lindor, N.M., Wang, X., Godwin, A.K., Caligo, M.A., Lombardi, G., Loman, N., Karlsson, P., Ehrencrona, H., Wachenfeldt, A. von, Bjork Barkardottir, R., Hamann, U., Rashid, M.U., Lasa, A., Caldes, T., Andres, R., Schmitt, M., Assmann, V., Stevens, K., Offit, K., Curado, J., Tilgner, H., Guigo, R., Aiza, G., Brunet, J., Castellsague, J., Martrat, G., Urruticoechea, A., Blanco, I., Tihomirova, L.

Publikováno v: Plos Biology, 9, 11, pp. e1001199-e1001199
Plos Biology, 9, e1001199-e1001199

Contains fulltext : 98031.pdf (Publisher’s version ) (Open Access) Differentiated mammary epithelium shows apicobasal polarity, and loss of tissue organization is an early hallmark of breast carcinogenesis. In BRCA1 mutation carriers, accumulation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9824ded3094a26e41c4119f4f102b381
https://hdl.handle.net/2066/98031

Exploring the link between MORF4L1 and risk of breast cancer

Autor: Martrat, G., Maxwell, C.A., Tominaga, E., Porta-de-la-Riva, M., Bonifaci, N., Gomez-Baldo, L., Bogliolo, M., Lazaro, C., Blanco, I., Brunet, J., Aguilar, H., Fernandez-Rodriguez, J., Seal, S., Renwick, A., Rahman, N., Kuhl, J., Neveling, K., Schindler, D., Ramirez, M.J., Castella, M., Hernandez, G., Easton, D.F., Peock, S., Cook, M., Oliver, C.T., Frost, D., Platte, R., Evans, D.G., Lalloo, F., Eeles, R., Izatt, L., Chu, C., Davidson, R., Ong, K.R., Cook, J., Douglas, F., Hodgson, S., Brewer, C., Morrison, P.J., Porteous, M., Peterlongo, P., Manoukian, S., Peissel, B., Zaffaroni, D., Roversi, G., Barile, M., Viel, A., Pasini, B., Ottini, L., Putignano, A.L., Savarese, A., Bernard, L., Radice, P., Healey, S., Spurdle, A., Chen, X.Q., Beesley, J., Rookus, M.A., Verhoef, S., Tilanus-Linthorst, M.A., Vreeswijk, M.P., Asperen, C.J., Bodmer, D., Ausems, M.G.E.M., Os, T.A. van, Blok, M.J., Meijers-Heijboer, H.E.J., Hogervorst, F.B.L., Goldgar, D.E., Buys, S., John, E.M., Miron, A., Southey, M., Daly, M.B., Harbst, K., Borg, A., Rantala, J., Barbany-Bustinza, G., Ehrencrona, H., Stenmark-Askmalm, M., Kaufman, B., Laitman, Y., Milgrom, R., Friedman, E., Domchek, S.M., Nathanson, K.L., Rebbeck, T.R., Oskar, T., Couch, F.J., Wang, X.S., Fredericksen, Z., Cuadras, D., Moreno, V., Pientka, F.K., Depping, R., Caldes, T., Osorio, A., Benitez, J., Bueren, J., Heikkinen, T., Nevanlinna, H., Hamann, U., Torres, D., Caligo, M.A., Godwin, A.K., Imyanitov, E.N., Janavicius, R., Sinilnikova, O.M., Stoppa-Lyonnet, D., Mazoyer, S., Verny-Pierre, C., Castera, L., Pauw, A. de, Bignon, Y.J., Uhrhammer, N., Peyrat, J.P., Vennin, P., Ferrer, S.F., Collonge-Rame, M.A., Mortemousque, I., McGuffog, L., Chenevix-Trench, G., Pereira-Smith, O.M., Antoniou, A.C., Ceron, J., Tominaga, K., Surralles, J., Pujana, M.A., EMBRACE, kConFab, HEBON, BCFR, SWE-BRCA, GEMO Study Collaborators

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
instname
Breast cancer research, 13(2). BioMed Central
Breast Cancer Research
Breast Cancer Research, 2011, 13 (2), pp.R40. ⟨10.1186/bcr2862⟩
Dipòsit Digital de la UB
Universidad de Barcelona
Breast Cancer Research, BioMed Central, 2011, 13 (2), pp.R40. ⟨10.1186/bcr2862⟩
Breast Cancer Research, 13(2). BioMed Central Ltd.
Breast Cancer Research, 13(2). BioMed Central
Breast Cancer Research, 13(2)
Breast Cancer Research, 13, R40-R40
Breast Cancer Research, 13(2). BioMed Central Ltd
Martrat, G, Maxwell, C A, Tominaga, E, Porta-de-la-Riva, M, Bonifaci, N, Gomez-Baldo, L, Bogliolo, M, Lazaro, C, Blanco, I, Brunet, J, Aguilar, H, Fernandez-Rodriguez, J, Seal, S, Renwick, A, Rahman, N, Kuhl, J, Neveling, K, Schindler, D, Ramirez, M J, Castella, M, Hernandez, G, Easton, D F, Peock, S, Cook, M, Oliver, C T, Frost, D, Platte, R, Evans, D G, Lalloo, F, Eeles, R, Izatt, L, Chu, C, Davidson, R, Ong, K R, Cook, J, Douglas, F, Hodgson, S, Brewer, C, Morrison, P J, Porteous, M, Peterlongo, P, Manoukian, S, Peissel, B, Zaffaroni, D, Roversi, G, Barile, M, Viel, A, Pasini, B, Ottini, L, Putignano, A L, Savarese, A, Bernard, L, Radice, P, Healey, S, Spurdle, A, Chen, X Q, Beesley, J, Rookus, M A, Verhoef, S, Tilanus-Linthorst, M A, Vreeswijk, M P, van Asperen, C J, Bodmer, D, Ausems, M G E M, Os, T A, Blok, M J, Meijers-Heijboer, E J, Hogervorst, F B L, Goldgar, D E, Buys, S, John, E M, Miron, A, Southey, M, Daly, M B, Harbst, K, Borg, A, Rantala, J, Barbany-Bustinza, G, Ehrencrona, H, Stenmark-Askmalm, M, Kaufman, B, Laitman, Y, Milgrom, R, Friedman, E, Domchek, S M, Nathanson, K L, Rebbeck, T R, Oskar, T, Couch, F J, Wang, X S, Fredericksen, Z, Cuadras, D, Moreno, V, Pientka, F K, Depping, R, Caldes, T, Osorio, A, Benitez, J, Bueren, J & Pujana, M A 2011, ' Exploring the link between MORF4L1 and risk of breast cancer ', Breast Cancer Research, vol. 13, no. 2, R40 . https://doi.org/10.1186/bcr2862
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Breast Cancer Research; 13(2), no R40 (2011)
Breast Cancer Research : BCR
Breast Cancer Research, 13(2):R40. BioMed Central
Breast Cancer Research, 13, 2, pp. R40-R40
Breast Cancer Research, BioMed Central, 2011, 13 (2), pp.R40. 〈10.1186/bcr2862〉

Introduction Proteins encoded by Fanconi anemia (FA) and/or breast cancer (BrCa) susceptibility genes cooperate in a common DNA damage repair signaling pathway. To gain deeper insight into this pathway and its influence on cancer risk, we searched fo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abac05e4774bd4a56523f90f1e90589
http://hdl.handle.net/2445/124234

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