Loss of heterozygosity : its impact on generating and shaping genetic variations in human fungal pathogen candida albicans

Autor: Marton, Timea B.

Publikováno v: Human health and pathology. Université Paris Cité, 2020. English. ⟨NNT : 2020UNIP7111⟩
Human health and pathology. Université de Paris, 2020. English. ⟨NNT : 2020UNIP7111⟩

Candida albicans is an opportunistic human pathogen possessing a relatively heterozygous diploid genome that is highly tolerant to particular genomic rearrangements, namely loss-of-heterozygosity (LOH). These two genomic hallmarks are thought to part

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