Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Martino L. Di Salvo"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Externí odkaz:
https://doaj.org/article/5fb2130b30f2419696fe14ec58731eb8
Autor:
Vasily A. Aleshin, Anastasia V. Graf, Artem V. Artiukhov, Alexandra I. Boyko, Alexander L. Ksenofontov, Maria V. Maslova, Isabel Nogués, Martino L. di Salvo, Victoria I. Bunik
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 737 (2021)
The disturbed metabolism of vitamins B1 or B6, which are essential for neurotransmitters homeostasis, may cause seizures. Our study aims at revealing therapeutic potential of vitamins B1 and B6 by estimating the short- and long-term effects of their
Externí odkaz:
https://doaj.org/article/f9a0968204bc444d8af13175f4f576c4
Autor:
Martino L. di Salvo, Mario Mastrangelo, Isabel Nogués, Manuela Tolve, Alessandro Paiardini, Carla Carducci, Davide Mei, Martino Montomoli, Angela Tramonti, Renzo Guerrini, Roberto Contestabile, Vincenzo Leuzzi
Publikováno v:
Data in Brief, Vol 15, Iss , Pp 868-875 (2017)
PNPO deficiency is responsible of severe neonatal encephalopathy, responsive to pyridoxal-5â²-phosphate (PLP) or pyridoxine. Recent studies widened the phenotype of this condition and detected new genetic variants on PNPO gene, whose pathogenetic r
Externí odkaz:
https://doaj.org/article/f013bfa8128d460e9bc017bc7e8ce9de
Autor:
Caterina Nardella, Dalila Boi, Martino L. di Salvo, Anna Barile, Jörg Stetefeld, Angela Tramonti, Roberto Contestabile
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
Plants, algae and most bacteria synthesize 5-aminolevulinic acid (ALA), the universal precursor of tetrapyrroles such as heme, chlorophyll and coenzyme B12, by a two-step transformation involving the NADPH-dependent glutamyl-tRNA reductase (HemA), wh
Externí odkaz:
https://doaj.org/article/f6b62f13cb774065ae47e035283aa94c
Autor:
Angela Tramonti, Roberto Contestabile, Rita Florio, Caterina Nardella, Anna Barile, Martino L. Di Salvo
Publikováno v:
Life, Vol 11, Iss 5, p 438 (2021)
Cysteine sulfinic acid decarboxylase catalyzes the last step of taurine biosynthesis in mammals, and belongs to the fold type I superfamily of pyridoxal-5′-phosphate (PLP)-dependent enzymes. Taurine (2-aminoethanesulfonic acid) is the most abundant
Externí odkaz:
https://doaj.org/article/7569477c869648469525d2f3462ded59
Autor:
Isabel Nogués, Victoria I. Bunik, Roberto Contestabile, Angela Tramonti, Anna Barile, Martino L. di Salvo
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports
Scientific reports (Nature Publishing Group) 10 (2020). doi:10.1038/s41598-020-70598-7
info:cnr-pdr/source/autori:Barile, Anna; Nogués, Isabel; di Salvo, Martino L.; Bunik, Victoria; Contestabile, Roberto; Tramonti, Angela/titolo:Molecular characterization of pyridoxine 5'-phosphate oxidase and its pathogenic forms associated with neonatal epileptic encephalopathy/doi:10.1038%2Fs41598-020-70598-7/rivista:Scientific reports (Nature Publishing Group)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Scientific Reports
Scientific reports (Nature Publishing Group) 10 (2020). doi:10.1038/s41598-020-70598-7
info:cnr-pdr/source/autori:Barile, Anna; Nogués, Isabel; di Salvo, Martino L.; Bunik, Victoria; Contestabile, Roberto; Tramonti, Angela/titolo:Molecular characterization of pyridoxine 5'-phosphate oxidase and its pathogenic forms associated with neonatal epileptic encephalopathy/doi:10.1038%2Fs41598-020-70598-7/rivista:Scientific reports (Nature Publishing Group)/anno:2020/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Defects of vitamin B6 metabolism are responsible for severe neurological disorders, such as pyridoxamine 5′-phosphate oxidase deficiency (PNPOD; OMIM: 610090), an autosomal recessive inborn error of metabolism that usually manifests with neonatal-o
Autor:
Elisa Mascolo, Francesco Liguori, Chiara Merigliano, Ludovica Schiano, Eleonora Gnocchini, Eleonora Pilesi, Cinzia Volonté, Martino L. Di Salvo, Roberto Contestabile, Angela Tramonti, Fiammetta Vernì
Publikováno v:
Journal of cellular physiology (Online) (2022). doi:10.1002/jcp.30812
info:cnr-pdr/source/autori:Mascolo E, Liguori F, Merigliano C, Schiano L, Gnocchini E, Pilesi E, Volonté C, Di Salvo ML, Contestabile R, Tramonti A, Vernì F/titolo:Vitamin B6 rescues insulin resistance and glucose-induced DNA damage caused by reduced activity of Drosophila PI3K/doi:10.1002%2Fjcp.30812/rivista:Journal of cellular physiology (Online)/anno:2022/pagina_da:/pagina_a:/intervallo_pagine:/volume
info:cnr-pdr/source/autori:Mascolo E, Liguori F, Merigliano C, Schiano L, Gnocchini E, Pilesi E, Volonté C, Di Salvo ML, Contestabile R, Tramonti A, Vernì F/titolo:Vitamin B6 rescues insulin resistance and glucose-induced DNA damage caused by reduced activity of Drosophila PI3K/doi:10.1002%2Fjcp.30812/rivista:Journal of cellular physiology (Online)/anno:2022/pagina_da:/pagina_a:/intervallo_pagine:/volume
The insulin signaling pathway controls cell growth and metabolism, thus its deregulation is associated with both cancer and diabetes. Phosphatidylinositol 3-kinase (PI3K) contributes to the cascade of phosphorylation events occurring in the insulin p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a2f4a1a8f374c4b4bc201636921c8df
http://hdl.handle.net/11573/1641668
http://hdl.handle.net/11573/1641668
Autor:
Claudio Graziani, Victoria I. Bunik, Roberto Contestabile, Anna Barile, Martino L. di Salvo, Peter E. Clayton, Philippa B. Mills, Angela Tramonti
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 21
International journal of molecular sciences
22 (2021). doi:10.3390/ijms222112013
info:cnr-pdr/source/autori:Barile, Anna; Mills, Philippa; Di Salvo, Martino L.; Graziani, Claudio; Bunik, Victoria; Clayton, Peter; Contestabile, Roberto; Tramonti, Angela/titolo:Characterization of novel pathogenic variants causing pyridox(am)ine 5'-phosphate oxidase-dependent epilepsy/doi:10.3390%2Fijms222112013/rivista:International journal of molecular sciences (Print)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:22
International Journal of Molecular Sciences, Vol 22, Iss 12013, p 12013 (2021)
Volume 22
Issue 21
International journal of molecular sciences
22 (2021). doi:10.3390/ijms222112013
info:cnr-pdr/source/autori:Barile, Anna; Mills, Philippa; Di Salvo, Martino L.; Graziani, Claudio; Bunik, Victoria; Clayton, Peter; Contestabile, Roberto; Tramonti, Angela/titolo:Characterization of novel pathogenic variants causing pyridox(am)ine 5'-phosphate oxidase-dependent epilepsy/doi:10.3390%2Fijms222112013/rivista:International journal of molecular sciences (Print)/anno:2021/pagina_da:/pagina_a:/intervallo_pagine:/volume:22
International Journal of Molecular Sciences, Vol 22, Iss 12013, p 12013 (2021)
Several variants of the enzyme pyridox(am)ine 5′-phosphate oxidase (PNPO), responsible for a rare form of vitamin B6-dependent neonatal epileptic encephalopathy known as PNPO deficiency (PNPOD), have been reported. However, only a few of them have
Autor:
Alexander L. Ksenofontov, Vasily A. Aleshin, Martino L. di Salvo, Alexandra Boyko, Anastasia Graf, Victoria I. Bunik, Artem V. Artiukhov, Isabel Nogués, M. V. Maslova
Disturbed metabolism of vitamins B1 or B6, which are essential for neurotransmitters homeostasis, may cause epilepsy. Our study aims at revealing therapeutic potential of vitamins B1 and B6 in epilepsy by estimating effects of their combined administ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d9099280b729203c69ec3d7117c0677
https://doi.org/10.20944/preprints202105.0034.v1
https://doi.org/10.20944/preprints202105.0034.v1
Autor:
Angela, Tramonti, Caterina, Nardella, Martino L, di Salvo, Anna, Barile, Federico, D'Alessio, Valérie, de Crécy-Lagard, Roberto, Contestabile
Publikováno v:
EcoSal Plus
Vitamin B(6) is an ensemble of six interconvertible vitamers: pyridoxine (PN), pyridoxamine (PM), pyridoxal (PL), and their 5’-phosphate derivatives PNP, PMP, and PLP. Pyridoxal 5’-phosphate is a coenzyme in a variety of enzyme reactions concerni