Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Martino Gabra"'
Autor:
Vanisha Patel, Vivesh Patel, Faraj Abdallah, Daniel Whelan, Shikha Bansal, Martino Gabra, Richard Brull
Publikováno v:
Regional Anesthesia & Pain Medicine. 47:733-737
IntroductionThe novel pericapsular nerve group (PENG) block has recently been reported to provide effective motor-sparing local anesthetic-based analgesia to the hip joint. We aimed to evaluate the analgesic efficacy and safety of a preoperative PENG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::694783fd9cdb5c11ccd295f489a86acf
https://doi.org/10.1136/rapm-2022-103743
https://doi.org/10.1136/rapm-2022-103743
Autor:
Gabriela Krivdova, Brian Yee, Stefan Aigner, Martino Gabra, Alexander Shishkin, Long Nguyen, Jessica L McLeod, Leah Carley, Leonardo Salmena, Lorien Shakib, Mark D. Minden, Eric L Van Nostrand, Gene W. Yeo, Eric R. Lechman, John E. Dick
Publikováno v:
Blood. 140:8684-8685
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::394d02669a48fa2e472b54180344fe06
https://doi.org/10.1182/blood-2022-169849
https://doi.org/10.1182/blood-2022-169849
Autor:
Veronique Voisin, Erwin M. Schoof, Eric R. Lechman, Nathan Mbong, Andy G.X. Zeng, James A. Kennedy, Daniel D. De Carvalho, Gabriela Krivdova, Olga I. Gan, Gene W. Yeo, Leonardo Salmena, Gary D. Bader, John E. Dick, Elvin Wagenblast, Martino Gabra, Eric L. Van Nostrand, Mark D. Minden, Alexander Murison, Brian A. Yee, Stefan Aigner, Jessica McLeod, Sajid A. Marhon, Karin G. Hermans, Alexander A. Shishkin, Aaron Trotman-Grant
SUMMARYGene expression profiling and proteome analysis of normal and malignant hematopoietic stem cells (HSC) point to shared core stemness properties. However, discordance between mRNA and protein signatures underscores an important role for post-tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8e3b525e4acdf9d20d00d19dc43385d
https://doi.org/10.1101/2021.07.30.454489
https://doi.org/10.1101/2021.07.30.454489
Autor:
Emily Marie Mangialardi, Igor Jurisica, Leonardo Salmena, Daniel K.C. Lee, Meong Hi Son, John F. Woolley, Ruijuan He, Miki S. Gams, Ayesha Rashid, Jean Vacher, John E. Dick, Roberto J. Botelho, Martino Gabra, Erwin M. Schoof, Cynthia J. Guidos, Irakli Dzneladze, Gizem E. Genc, Max Kotlyar, Keyue Chen, Golam T. Saffi, Mark Minden, Stephanie Z. Xie
Signaling pathways that control vital features of leukemic stem cells including multipotency, self-renewal, clonal expansion and quiescence remain unclear. Emerging studies illustrate critical roles for lysosomes in hematopoietic and leukemic stem ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c069f4a36beb84cab3e5656a5d5597f2
https://doi.org/10.1101/2021.03.25.437029
https://doi.org/10.1101/2021.03.25.437029
Autor:
Johann Hitzler, Laura García-Prat, Sabrina A. Smith, Gabriela Krivdova, Daniel D. De Carvalho, Olga I. Gan, Maria Azkanaz, Leonardo Salmena, Maian Roifman, Elvin Wagenblast, Karen Chong, David Chitayat, John E. Dick, Alex Murison, Eric R. Lechman, Martino Gabra, Jessica McLeod, Sarah K Cutting, Jean C.Y. Wang, Sajid A. Marhon, Joana Araújo, Patrick Shannon, Michelle Chan-Seng-Yue
Children with Down syndrome have a 150-fold increased risk of developing myeloid leukemia, but the mechanism of predisposition is unclear. As Down syndrome leukemogenesis initiates during fetal development, we characterized the cellular context of pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5102fa236e1ee48daea0d4391094e5d2
https://doi.org/10.1101/2020.11.29.402800
https://doi.org/10.1101/2020.11.29.402800
Publikováno v:
Cold Spring Harb Perspect Med
Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a key tumor suppressor in the development and progression of different tumor types. Emerging data indicate that small reductions in PTEN protein levels can promote cancer. PTEN protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76401a44aeaa715e1adf8924b3c21156
https://pubmed.ncbi.nlm.nih.gov/31871240
https://pubmed.ncbi.nlm.nih.gov/31871240
Elevated Expression of Mir-130a in t(8,21) AML Reinforces the Aberrant Molecular Program of AML1-ETO
Autor:
Eric R. Lechman, Leonardo Salmena, Veronique Voisin, Schoof E Erwin, Jessica McLeod, Mark D. Minden, Sajid A. Marhon, Gabriela Krivdova, John E. Dick, Martino Gabra
Publikováno v:
Blood. 136:41-42
Background: Deregulation of self-renewal and differentiation programs are central to the pathogenesis of hematologic malignancies. MicroRNAs (miRNAs) represent a large class of post-transcriptional regulators that mediate repression of multiple targe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::524e3688acfd9e1c11cf00f9cfb6cfdf
https://doi.org/10.1182/blood-2020-142652
https://doi.org/10.1182/blood-2020-142652
Autor:
Max Kotlyar, Martino Gabra, Chiara Pastrello, Leonardo Salmena, Tomas Tokar, Machado N, Chow Jt, Igor Jurisica
MicroRNAs (miRNA) are small RNAs that function as key modulators of gene expression. Due to their promiscuity of binding, a single miRNA may regulate several genes and hence, multiple pathways simultaneously. In addition, the 3’-UTR of mRNA can be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30592b830689b1b32418c69a52f1f721
Publikováno v:
Cold Spring Harbor Perspectives in Medicine. 10:a036236
Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a key tumor suppressor in the development and progression of different tumor types. Emerging data indicate that small reductions in PTEN protein levels can promote cancer. PTEN protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d6d6b348ab5460c78a1303c479bcf9b
https://doi.org/10.1101/cshperspect.a036236
https://doi.org/10.1101/cshperspect.a036236
Autor:
Leonardo Salmena, Martino Gabra
Publikováno v:
Frontiers in Oncology, Vol 7 (2017)
Frontiers in Oncology
Frontiers in Oncology
Up until the early 2000’s, a functional role for microRNAs (miRNAs) was yet to be elucidated. With the advent of increasingly high-throughput and precise RNA sequencing techniques within the last two decades, it has become well established that miR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2c04d40c209242d718738e87c5c9bf0
https://doi.org/10.3389/fonc.2017.00255
https://doi.org/10.3389/fonc.2017.00255