Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Martino Avallone"'
Autor:
Facundo Peralta, Ana Abril Vidal Escobedo, Juliette López Hanotte, Martino Avallone, Tomas Björklund, Paula Cecilia Reggiani, Joaquín Pardo
Publikováno v:
Neurobiology of Disease, Vol 200, Iss , Pp 106612- (2024)
Astrocytes play key roles in the brain. When astrocyte support fails, neurological disorders follow, resulting in disrupted synaptic communication, neuronal degeneration, and cell death. We posit that astrocytes overexpressing neurotrophic factors, s
Externí odkaz:
https://doaj.org/article/d5b3c2eefcde4459a98d04ac1c2d9a61
Autor:
Jana Rájová, Marcus Davidsson, Martino Avallone, Morgan Hartnor, Patrick Aldrin-Kirk, Tiago Cardoso, Sara Nolbrant, Annelie Mollbrink, Petter Storm, Andreas Heuer, Malin Parmar, Tomas Björklund
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 381-394 (2023)
Cell therapy for Parkinson’s disease has experienced substantial growth in the past decades with several ongoing clinical trials. Despite increasing refinement of differentiation protocols and standardization of the transplanted neural precursors,
Externí odkaz:
https://doaj.org/article/6a1ba6995484483fa9e5ed0702cd0fd1
Autor:
Martino Avallone, Joaquín Pardo, Tadiwos F. Mergiya, Jana Rájová, Atte Räsänen, Marcus Davidsson, Malin Åkerblom, Luis Quintino, Darshan Kumar, Clive R. Bramham, Tomas Björklund
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
The activity-regulated cytoskeleton-associated (Arc) protein is essential for synaptic plasticity and memory formation. The Arc gene, which contains remnants of a structural GAG retrotransposon sequence, produces a protein that self-assembles into ca
Externí odkaz:
https://doaj.org/article/d8913b1da5ea409b971a24396f2ff4f3
Autor:
Luis Quintino, Angrit Namislo, Marcus Davidsson, Ludivine S. Breger, Patrick Kavanagh, Martino Avallone, Erika Elgstrand-Wettergren, Christina Isaksson, Cecilia Lundberg
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 11, Iss , Pp 29-39 (2018)
Regulation of therapeutic transgene expression can increase the safety of gene therapy interventions, especially when targeting critical organs such as the brain. Although several gene expression systems have been described, none of the current syste
Externí odkaz:
https://doaj.org/article/9302a85eb1ed493c8cb2b668494caab4
Autor:
Patrick Kavanagh, Luis Quintino, Patricia Garcia Jareño, Ludivine S. Breger, Martino Avallone, Cecilia Lundberg, Marcus Lockowandt, Emil Brännstrom
Publikováno v:
Gene Therapy
Glial cell-line derived neurotrophic factor (GDNF) is a promising therapeutic molecule to treat Parkinson’s disease. Despite an excellent profile in experimental settings, clinical trials testing GDNF have failed. One of the theories to explain the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ca1f584e3057701294ff642cd5c5f93
https://doi.org/10.1038/s41434-018-0049-0
https://doi.org/10.1038/s41434-018-0049-0
Publikováno v:
Neuropsychopharmacology
Neuropsychopharmacology, Nature Publishing Group, 2015, 40 (12), pp.2843-2851. ⟨10.1038/npp.2015.140⟩
Neuropsychopharmacology, Nature Publishing Group, 2015, 40 (12), pp.2843-2851. ⟨10.1038/npp.2015.140⟩
International audience; The lateral habenula (LHb) is viewed as a relay between the limbic system, the basal ganglia (BG), and monoaminergic neurons of the midbrain. If a prominent role has been evidenced in BG-mediated functions such as value-based
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59c0ed543c99783bad96c2cae4426262
https://europepmc.org/articles/PMC4864662/
https://europepmc.org/articles/PMC4864662/
