Chaperones and Ubiquitin Ligases Balance Mutant p53 Protein Stability in Esophageal and Other Digestive Cancers

Autor: Martinho, May San, Nancarrow, Derek J., Lawrence, Theodore S., Beer, David G., Ray, Dipankar

Publikováno v: In Cellular and Molecular Gastroenterology and Hepatology 2021 11(2):449-464

GRAIL1 Stabilizes Misfolded Mutant p53 through a Ubiquitin Ligase-Independent, Chaperone Regulatory Function.

Autor: Ray P; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan., Jaiswal S; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan., Ferrer-Torres D; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan., Wang Z; Department of Thoracic Surgery, University of Michigan, Ann Arbor, Michigan., Nancarrow D; Department of Thoracic Surgery, University of Michigan, Ann Arbor, Michigan., Curtin M; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan., Martinho MS; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan., Lacy SM; Department of Cellular and Molecular Biology, University of Michigan, Ann Arbor, Michigan., Kasturirangan S; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan., Thomas D; Department of Pathology, University of Michigan, Ann Arbor, Michigan., Spence JR; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan.; Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, Michigan.; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan., Truttmann MC; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan., Lagisetty KH; Department of Thoracic Surgery, University of Michigan, Ann Arbor, Michigan., Lawrence TS; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan., Wang TD; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan., Beer DG; Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan., Ray D; Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan.

Publikováno v: Molecular cancer research : MCR [Mol Cancer Res] 2024 Nov 01; Vol. 22 (11), pp. 996-1010.