Randomized trial investigating the utility of a liver tissue transcriptional biomarker in identifying adult liver transplant recipients not requiring maintenance immunosuppression.

Autor: Vionnet J; Institute of Liver Studies, King's College London University and King's College Hospital, London, United Kingdom; Transplantation Center, Service of Immunology and Allergy, and Service of Gastroenterology and Hepatology, University Hospital of Lausanne, Lausanne, Switzerland. Electronic address: julien.vionnet@kcl.ac.uk., Torres-Yaguana J; Institute of Liver Studies, King's College London University and King's College Hospital, London, United Kingdom. Electronic address: jorge.torres_yaguana@kcl.ac.uk., Miquel R; Institute of Liver Studies, King's College London University and King's College Hospital, London, United Kingdom; Liver Histopathology Laboratory, King's College Hospital, London, United Kingdom. Electronic address: rosa.miquel@nhs.net., Abraldes JG; Liver Unit, Division of Gastroenterology, Centre of Excellence for Gastrointestinal Inflammation and Immunity Research, University of Alberta, Edmonton, Canada. Electronic address: juan.g.abraldes@ualberta.ca., Wall J; Institute of Liver Studies, King's College London University and King's College Hospital, London, United Kingdom. Electronic address: jurate.wall@kcl.ac.uk., Kodela E; Institute of Liver Studies, King's College London University and King's College Hospital, London, United Kingdom. Electronic address: elisavet.2.kodela@kcl.ac.uk., Lozano JJ; Bioinformatic Platform, Biomedical Research Center in Hepatic and Digestive Diseases (CIBEREHD), Instituto de Salud Carlos III, Spain. Electronic address: juanjo.lozano@ciberehd.org., Ruiz P; Hospital Clinic Barcelona, IDIBAPS, University of Barcelona, Barcelona, Spain. Electronic address: paruiz@clinic.cat., Navasa M; Hospital Clinic Barcelona, IDIBAPS, University of Barcelona, Barcelona, Spain. Electronic address: miquel_navasa@hotmail.com., Marshall A; Royal Free Hospital, London, United Kingdom. Electronic address: aileen.marshall@nhs.net., Nevens F; University Hospital KU Leuven, Belgium. Electronic address: frederik.nevens@uzleuven.be., Gelson W; Addenbrooke's Hospital, Cambridge, United Kingdom. Electronic address: williamgelson@nhs.net., Leithead J; Addenbrooke's Hospital, Cambridge, United Kingdom. Electronic address: joanna.leithead@nhs.scot., Masson S; Newcastle NIHR Biomedical Research Centre, Newcastle upon Tyne Hospitals NHS Foundation Trust and Translational and Clinical Research Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom. Electronic address: steven.masson@nhs.net., Jaeckel E; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany. Electronic address: jaeckel.elmar.jaeckel@uhn.ca., Taubert R; Department of Gastroenterology, Hepatology, Infectious Diseases and Endocrinology, Hannover Medical School, Hannover, Germany. Electronic address: taubert.richard@mh-hannover.de., Tachtatzis P; Leeds Teaching Hospitals NHS Trust, Leeds, United Kingdom. Electronic address: ptachtatzis@mcw.edu., Eurich D; Charité, Berlin, Germany. Electronic address: dennis.eurich@charite.de., Simpson KJ; Edinburgh Royal Infirmary, Edinburgh, United Kingdom. Electronic address: kenneth.simpson@nhs.scot., Bonaccorsi-Riani E; Liver Transplant Unit, Cliniques Universitaires St-Luc, Brussels, Belgium. Electronic address: eliano.bonaccorsi@saintluc.uclouvain.be., Ferguson J; Queen Elizabeth Hospital, Birmingham, United Kingdom. Electronic address: james.ferguson@uhb.nhs.uk., Quaglia A; Royal Free Hospital, London, United Kingdom. Electronic address: alberto.quaglia@nhs.net., Demetris AJ; Department of Pathology, Division of Transplantation, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: demetrisaj@upmc.edu., Lesniak AJ; Department of Pathology, Division of Transplantation, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: lesniakaj@upmc.edu., Elstad M; School of Population Health and Environmental Sciences, King's College London, London, United Kingdom. Electronic address: maria.elstad@kcl.ac.uk., Delord M; School of Population Health and Environmental Sciences, King's College London, London, United Kingdom. Electronic address: marc.delord@kcl.ac.uk., Douiri A; School of Population Health and Environmental Sciences, King's College London, London, United Kingdom. Electronic address: abdel.douiri@kcl.ac.uk., Rebollo-Mesa I; School of Population Health and Environmental Sciences, King's College London, London, United Kingdom. Electronic address: irene.rebollomesa@ucb.com., Martinez-Llordella M; Institute of Liver Studies, King's College London University and King's College Hospital, London, United Kingdom; Quell Therapeutics, London, United Kingdom. Electronic address: m.martinez-llordella@quell-tx.com., Silva JAF; Immune Tolerance Network; Emory University, School of Medicine, Department of Surgery, Division of Transplantation, Atlanta, USA. Electronic address: jsilva@immunetolerance.org., Markmann JF; Penn Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address: james.markmann@pennmedicine.upenn.edu., Sánchez-Fueyo A; Institute of Liver Studies, King's College London University and King's College Hospital, London, United Kingdom. Electronic address: sanchez_fueyo@kcl.ac.uk.

Publikováno v: American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons [Am J Transplant] 2024 Dec 18. Date of Electronic Publication: 2024 Dec 18.

Molecular Characterization of Acute Cellular Rejection Occurring During Intentional Immunosuppression Withdrawal in Liver Transplantation

Autor: Bonaccorsi-Riani, E., Pennycuick, A., Londoño, M.-C., Lozano, J.-J., Benítez, C., Sawitzki, B., Martínez-Picola, M., Bohne, F., Martínez-Llordella, M., Miquel, R., Rimola, A., Sánchez-Fueyo, A. ^*

Publikováno v: In American Journal of Transplantation February 2016 16(2):484-496

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Dysregulated anti-oxidant signalling and compromised mitochondrial integrity negatively influence regulatory T cell function and viability in liver disease.

Autor: Vaikunthanathan T; Department of Inflammation Biology, Institute of Liver Studies, School of Immunology and Microbial Sciences, James Black Centre, King's College London, London, SE5 9NU, United Kingdom. Electronic address: trishan.1.vaikunthanathan@kcl.ac.uk., Landmann E; Department of Inflammation Biology, Institute of Liver Studies, School of Immunology and Microbial Sciences, James Black Centre, King's College London, London, SE5 9NU, United Kingdom. Electronic address: emmanuelle.1.landmann@kcl.ac.uk., Correa DM; Department of Inflammation Biology, Institute of Liver Studies, School of Immunology and Microbial Sciences, James Black Centre, King's College London, London, SE5 9NU, United Kingdom. Electronic address: diana.marin_correa@kcl.ac.uk., Romano M; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, 5th Floor, Tower Wing, Guy's Hospital, Great Maze Pond, London, SE1 9RT, United Kingdom. Electronic address: marco.romano@kcl.ac.uk., Trevelin SC; Department of Inflammation Biology, Institute of Liver Studies, School of Immunology and Microbial Sciences, James Black Centre, King's College London, London, SE5 9NU, United Kingdom. Electronic address: silviacellone@outlook.com., Peng Q; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, 5th Floor, Tower Wing, Guy's Hospital, Great Maze Pond, London, SE1 9RT, United Kingdom. Electronic address: qi.peng@kcl.ac.uk., Crespo E; Department of Inflammation Biology, Institute of Liver Studies, School of Immunology and Microbial Sciences, James Black Centre, King's College London, London, SE5 9NU, United Kingdom. Electronic address: elena.crespo@kcl.ac.uk., Corrado M; Bloomberg-Kimmel Institute for Cancer Immunotherapy and Department of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address: mcorrado@uni-koeln.de., Lozano JJ; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Joseph Stelzmannstrasse 26, 50931, Cologne, Germany. Electronic address: juanjo.lozano@ciberehd.org., Pearce EL; Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (CIBEREHD), Calle Rossello 153 Bajos, O8036, Barcelona, Spain. Electronic address: epearce6@jhmi.edu., Perpinan E; Department of Inflammation Biology, Institute of Liver Studies, School of Immunology and Microbial Sciences, James Black Centre, King's College London, London, SE5 9NU, United Kingdom. Electronic address: elena.perpinan_mas@kcl.ac.uk., Zoccarato A; Department of Immunometabolism, Max Planck Institute of Immunobiology & Epigenetics, Stübeweg 51, 79108, Freiburg, Germany. Electronic address: anna.zoccarato@kcl.ac.uk., Siew L; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, 5th Floor, Tower Wing, Guy's Hospital, Great Maze Pond, London, SE1 9RT, United Kingdom. Electronic address: leonard.siew@gstt.nhs.uk., Edwards-Hicks J; Centre for Liver and Gastroenterology Research and Birmingham National Institute for Health Research (NIHR) Birmingham Biomedical Research Centre, Institute of Immunology and Immunotherapy, University of Birmingham, Birmingham, United Kingdom. Electronic address: je446@cam.ac.uk., Khan R; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College London, Liver Unit, 10th Floor QEQM Building, St Mary's Hospital, W2 1NY, London, United Kingdom. Electronic address: rsk409@student.bham.ac.uk., Luu NT; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College London, Liver Unit, 10th Floor QEQM Building, St Mary's Hospital, W2 1NY, London, United Kingdom. Electronic address: n.luu@bham.ac.uk., Thursz MR; Institute of Liver Sciences, King's College Hospital NHS Foundation Trust, London, SE5 9NU, United Kingdom. Electronic address: m.thursz@imperial.ac.uk., Newsome PN; Division of Digestive Diseases, Department of Metabolism, Digestion and Reproduction, Imperial College London, Liver Unit, 10th Floor QEQM Building, St Mary's Hospital, W2 1NY, London, United Kingdom. Electronic address: p.n.newsome@bham.ac.uk., Martinez-Llordella M; Department of Inflammation Biology, Institute of Liver Studies, School of Immunology and Microbial Sciences, James Black Centre, King's College London, London, SE5 9NU, United Kingdom. Electronic address: marc.martinez-llordella@kcl.ac.uk., Shah N; James Black Centre, Department of Cardiovascular sciences, British Heart Foundation Centre of Excellence, School of Cardiovascular and Metabolic Medicine and Sciences, King's College London, London, SE5 9NU, United Kingdom. Electronic address: naina.shah1@nhs.net., Lechler RI; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, 5th Floor, Tower Wing, Guy's Hospital, Great Maze Pond, London, SE1 9RT, United Kingdom. Electronic address: robert.lechler@kcl.ac.uk., Shah AM; Department of Immunometabolism, Max Planck Institute of Immunobiology & Epigenetics, Stübeweg 51, 79108, Freiburg, Germany. Electronic address: ajay.shah@kcl.ac.uk., Sanchez-Fueyo A; Department of Inflammation Biology, Institute of Liver Studies, School of Immunology and Microbial Sciences, James Black Centre, King's College London, London, SE5 9NU, United Kingdom. Electronic address: sanchez_fueyo@kcl.ac.uk., Lombardi G; Peter Gorer Department of Immunobiology, School of Immunology and Microbial Sciences, King's College London, 5th Floor, Tower Wing, Guy's Hospital, Great Maze Pond, London, SE1 9RT, United Kingdom. Electronic address: giovanna.lombardi@kcl.ac.uk., Safinia N; Department of Inflammation Biology, Institute of Liver Studies, School of Immunology and Microbial Sciences, James Black Centre, King's College London, London, SE5 9NU, United Kingdom. Electronic address: niloufar.1.safinia@kcl.ac.uk.

Publikováno v: EBioMedicine [EBioMedicine] 2023 Sep; Vol. 95, pp. 104778. Date of Electronic Publication: 2023 Aug 30.

Low dose interleukin-2 selectively expands circulating regulatory T cells but fails to promote liver allograft tolerance in humans.

Autor: Lim TY; Institute of Liver Studies, King's College Hospital, Medical Research Council (MRC) Centre for Transplantation, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK., Perpiñán E; Institute of Liver Studies, King's College Hospital, Medical Research Council (MRC) Centre for Transplantation, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK., Londoño MC; Institute of Liver Studies, King's College Hospital, Medical Research Council (MRC) Centre for Transplantation, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK; Liver Unit, Hospital Clínic Barcelona, IDIBAPS, CIBERehd, Barcelona, Spain., Miquel R; Institute of Liver Studies, King's College Hospital, Medical Research Council (MRC) Centre for Transplantation, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK; Liver Histopathology Laboratory, King's College Hospital, London, UK., Ruiz P; Institute of Liver Studies, King's College Hospital, Medical Research Council (MRC) Centre for Transplantation, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK., Kurt AS; Institute of Liver Studies, King's College Hospital, Medical Research Council (MRC) Centre for Transplantation, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK., Kodela E; Institute of Liver Studies, King's College Hospital, Medical Research Council (MRC) Centre for Transplantation, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK., Cross AR; Transplantation Research Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK., Berlin C; Transplantation Research Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK., Hester J; Transplantation Research Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK., Issa F; Transplantation Research Immunology Group, Nuffield Department of Surgical Sciences, University of Oxford, John Radcliffe Hospital, Oxford, UK., Douiri A; School of Population Health and Environmental Sciences, King's College London, London, UK., Volmer FH; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Taubert R; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Williams E; Department of Immunobiology, School of Immunology & Microbial Sciences (SIMS), King's College London, London, UK., Demetris AJ; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA., Lesniak A; Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA., Bensimon G; Département de Pharmacologie Clinique, Hôpital de la Pitié-Salpêtrière et UPMC Pharmacologie, Paris-Sorbonne Université, Paris, France; Laboratoire de Biostatistique, Epidémiologie Clinique, Santé Publique Innovation et Méthodologie (BESPIM), CHU-Nîmes, Nîmes, France., Lozano JJ; Bioinformatic Platform, Biomedical Research Center in Hepatic and Digestive Diseases (CIBEREHD), Carlos III Health Institute, Barcelona, Spain., Martinez-Llordella M; Institute of Liver Studies, King's College Hospital, Medical Research Council (MRC) Centre for Transplantation, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK., Tree T; Department of Immunobiology, School of Immunology & Microbial Sciences (SIMS), King's College London, London, UK., Sánchez-Fueyo A; Institute of Liver Studies, King's College Hospital, Medical Research Council (MRC) Centre for Transplantation, School of Immunology & Microbial Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK. Electronic address: sanchez_fueyo@kcl.ac.uk.

Publikováno v: Journal of hepatology [J Hepatol] 2023 Jan; Vol. 78 (1), pp. 153-164. Date of Electronic Publication: 2022 Sep 07.