Výsledky vyhledávání - "Martinez-Chantar ML"

Keywords: Non-Alcoholic Fatty Liver Disease (NAFLD); Non-alcoholic steatohepatitis (NASH); Hepatocellular carcinoma (HCC); Nuclear factor of activated T cells 4 (NFATc4); PPARa; Osteopontin. Non-alcoholic fatty liver disease (NAFLD) has emerged as on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e989ae37a1af3176918760c4172e0f0

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The Balance between Mono- and NEDD8-Chains Controlled by NEDP1 upon DNA Damage Is a Regulatory Module of the HSP70 ATPase Activity

Autor: Bailly AP, Perrin A, Serrano-Macia M, Maghames C, Leidecker O, Trauchessec H, Martinez-Chantar ML, Gartner A, Xirodimas DP.

SUMMARY Ubiquitin and ubiquitin-like chains are finely balanced by conjugating and de-conjugating enzymes. Alterations in this balance trigger the response to stress conditions and are often observed in pathologies. How such changes are detected is n

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AISF position paper on liver transplantation and pregnancy: Women in Hepatology Group, Italian Association for the Study of the Liver (AISF)

After the first successful pregnancy in a liver transplant recipient in 1978, much evidence has accumulated on the course, outcomes and management strategies of pregnancy following liver transplantation. Generally, liver transplantation restores sexu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::56dbbd7a214db1de238af8d26ad1944e
http://hdl.handle.net/2158/1168916

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The immunosuppressive effect of the tick salivary protein, Salp15, is persistent and has long-term effects in a murine model of hematopoietic transplant

Autor: Tomás-Cortazar J, Martín-Ruiz I, Barriales D, Pascual-Itoiz MA, Gutierrez de Juan V, Caro-Maldonado A, Merino N, Marina A, Blanco F, Sutherland JD, Barrio R, Rojas A, Martinez-Chantar ML, Carracedo A, Simó C, García-Cañas V, Abecia L, Lavín JL, Aransay AM, Rodríguez H, Anguita J

Salp15, a salivary protein of Ixodes ticks, inhibits the activation of naïve CD4 T cells. Treatment with Salp15 results in the inhibition of early signaling events and the production of the autocrine growth factor, interleukin-2. The fate of the CD4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2659::df05f208ea7eb923a12bcc65637d87cc
https://zenodo.org/record/2640517

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mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer

Autor: Zabala-Letona A, Arruabarrena-Aristorena A, Martín-Martín N, Fernandez-Ruiz S, Sutherland JD, Clasquin M, Tomas-Cortazar J, Jimenez J, Torres I, Quang P, Ximenez-Embun P, Bago R, Ugalde-Olano A, Loizaga-Iriarte A, Lacasa-Viscasillas I, Unda M, Torrano V, Cabrera D, van Liempd SM, Cendon Y, Castro E, Murray S, Revandkar A, Alimonti A, Zhang Y, Barnett A, Lein G, Pirman D, Cortazar AR, Arreal L, Prudkin L, Astobiza I, Valcarcel-Jimenez L, Zuñiga-García P, Fernandez-Dominguez I, Piva M, Caro-Maldonado A, Sánchez-Mosquera P, Castillo-Martín M, Serra V, Beraza N, Gentilella A, Thomas G, Azkargorta M, Elortza F, Farràs R, Olmos D, Efeyan A, Anguita J, Muñoz J, Falcón-Pérez JM, Barrio R, Macarulla T, Mato JM, Martinez-Chantar ML, Cordon-Cardo C, Aransay AM, Marks K, Baselga J, Tabernero J, Nuciforo P, Manning BD, Marjon K, Carracedo A

Activation of the PTEN-PI3K-mTORC1 pathway consolidates metabolic programs that sustain cancer cell growth and proliferation1,2. Here we show that mTORC1 regulates polyamine dynamics, a metabolic route that is essential for oncogenicity. Through the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2659::824535b8c51e40827ce59dc4e0b74b8d
https://zenodo.org/record/2640538

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S-Adenosylmethionine revisited: its essential role in the regulation of liver function

Autor: Avila, Ma, Garcia-Trevijano, Er, Martinez-Chantar, Ml, Latasa, Mu, Perez-Mato, I., Martinez-Cruz, La, Del Pino, Mms, Corrales, Fj, José Mato

Publikováno v: Dadun. Depósito Académico Digital de la Universidad de Navarra
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Dietary methionine is mainly metabolized in the liver where it is converted into S-adenosylmethionine (AdoMet), the main biologic methyl donor. This reaction is catalyzed by methionine adenosyltransferase I/III (MAT I/III), the product of MAT1A gene,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cc8903db4ce390e261ecdac9fe5ebff6
https://hdl.handle.net/10171/21381

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Akademický článek

Post-translational modifiers of liver kinase B1/serine/threonine kinase 11 in hepatocellular carcinoma

Autor: Delgado TC, Lopitz-Otsoa F, Martínez-Chantar ML

Publikováno v: Journal of Hepatocellular Carcinoma, Vol Volume 6, Pp 85-91 (2019)

Teresa Cardoso Delgado, Fernando Lopitz-Otsoa, María Luz Martínez-ChantarLiver Disease and Liver Metabolism Laboratories, CIC bioGUNE, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Derio 48160, Bizka

Externí odkaz: https://doaj.org/article/2449c3f597264347a1f89c858125f770

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