Altered excitatory and inhibitory neocortical circuitry leads to increased convulsive severity after pentylenetetrazol injection in an animal model of schizencephaly, but not of microgyria.

Autor: Dos Santos Heringer L; Neurodegeneration and Repair Lab, Department of Pathology, Postgraduate Program in Anatomical Pathology, Faculty of Medicine, Universitary Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Rios Carvalho J; Neurodegeneration and Repair Lab, Department of Pathology, Postgraduate Program in Anatomical Pathology, Faculty of Medicine, Universitary Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Teixeira Oliveira J; D'Or Institute for Research and Teaching, Rio de Janeiro, Brazil., Texeira Silva B; Laboratory of Neuroplasticity, Department of Neurobiology, Institute of Biology, Fluminense Federal University, Niterói, Brazil., de Souza Aguiar Dos Santos DM; Neurodegeneration and Repair Lab, Department of Pathology, Postgraduate Program in Anatomical Pathology, Faculty of Medicine, Universitary Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Martinez Martinez Toledo AL; Neurodegeneration and Repair Lab, Department of Pathology, Postgraduate Program in Anatomical Pathology, Faculty of Medicine, Universitary Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Borges Savoldi LM; Neurodegeneration and Repair Lab, Department of Pathology, Postgraduate Program in Anatomical Pathology, Faculty of Medicine, Universitary Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Magalhães Portela D; Integrated Lab of Morphology, Institute of Biodiversity and Sustainability NUPEM, Multicentric Postgraduate Program in Physiological Sciences - SBFis, Federal University of Rio de Janeiro, Brazil., Adriani Marques S; Neurodegeneration and Repair Lab, Department of Pathology, Postgraduate Program in Anatomical Pathology, Faculty of Medicine, Universitary Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Campello Costa Lopes P; Laboratory of Neuroplasticity, Department of Neurobiology, Institute of Biology, Fluminense Federal University, Niterói, Brazil., Blanco Martinez AM; Neurodegeneration and Repair Lab, Department of Pathology, Postgraduate Program in Anatomical Pathology, Faculty of Medicine, Universitary Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Rocha Mendonça H; Neurodegeneration and Repair Lab, Department of Pathology, Postgraduate Program in Anatomical Pathology, Faculty of Medicine, Universitary Hospital Clementino Fraga Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.; Integrated Lab of Morphology, Institute of Biodiversity and Sustainability NUPEM, Multicentric Postgraduate Program in Physiological Sciences - SBFis, Federal University of Rio de Janeiro, Brazil.

Publikováno v: Epilepsia open [Epilepsia Open] 2022 Sep; Vol. 7 (3), pp. 462-473. Date of Electronic Publication: 2022 Jul 21.