Engineering large-scale hiPSC-derived vessel-integrated muscle-like lattices for enhanced volumetric muscle regeneration.

Autor: Lee MC; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA; Medicinal Materials Research Center, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea., Jodat YA; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA., Endo Y; Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Rodríguez-delaRosa A; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Harvard University, Boston, MA 02138, USA., Zhang T; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA; Department of Mechanical Engineering, Tsinghua University, Beijing 100084, China., Karvar M; Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Al Tanoury Z; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Harvard University, Boston, MA 02138, USA., Quint J; Department of Biomedical Engineering, University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Mechanical and Materials Engineering, University of Nebraska, Lincoln, Lincoln, NE 68588, USA., Kamperman T; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA., Kiaee K; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA., Ochoa SL; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA., Shi K; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA., Huang Y; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA., Rosales MP; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA., Arnaout A; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA., Lee H; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA., Kim J; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA., Ceron EL; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA., Reyes IG; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA., Panayi AC; Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Martinez AFH; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA., Wang X; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA., Kim KT; Department of Molecular Genetics, School of Dentistry and Dental Research Institute, Dental Multi-omics Center, Seoul National University, Seoul 08826, Republic of Korea; Epigenetic Regulation of Aged Skeleto-Muscular System Laboratory, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 08826, Republic of Korea., Moon JI; Department of Molecular Genetics, School of Dentistry and Dental Research Institute, Dental Multi-omics Center, Seoul National University, Seoul 08826, Republic of Korea; Epigenetic Regulation of Aged Skeleto-Muscular System Laboratory, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 08826, Republic of Korea., Park SG; Department of Molecular Genetics, School of Dentistry and Dental Research Institute, Dental Multi-omics Center, Seoul National University, Seoul 08826, Republic of Korea; Epigenetic Regulation of Aged Skeleto-Muscular System Laboratory, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 08826, Republic of Korea., Lee K; Department of Healthcare and Medical Engineering, Chonnam National University, Yeosu 59626, Republic of Korea., Calabrese MA; Chemical Engineering and Materials Science Department, University of Minnesota, Minneapolis, MN 55455, USA., Hassan S; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA; Department of Biological Sciences, Khalifa University, Abu Dhabi 127788, United Arab Emirates; Biotechnology Center (BTC), Khalifa University, Abu Dhabi 127788, United Arab Emirates., Lee J; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA; Department of Materials Science and Engineering, Pohang University of Science and Technology (POSTECH), Pohang 37673, Republic of Korea., Tamayol A; Department of Biomedical Engineering, University of Connecticut Health Center, Farmington, CT 06030, USA; Department of Mechanical and Materials Engineering, University of Nebraska, Lincoln, Lincoln, NE 68588, USA., Lee L; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA; Department of Bioengineering, University of California, Berkeley, Berkeley, CA 94720, USA; Department of Electrical Engineering and Computer Science, University of California, Berkeley, Berkeley, CA 94720, USA; Department of Biophysics, Institute of Quantum Biophysics, Sungkyunkwan University, Suwon, Republic of Korea; Department of Chemistry and Nanoscience, Ewha Womans University, Seoul, Republic of Korea., Pourquié O; Department of Pathology, Brigham and Women's Hospital, Boston, MA 02115, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA; Harvard Stem Cell Institute, Harvard University, Boston, MA 02138, USA., Kim WJ; Department of Molecular Genetics, School of Dentistry and Dental Research Institute, Dental Multi-omics Center, Seoul National University, Seoul 08826, Republic of Korea; Epigenetic Regulation of Aged Skeleto-Muscular System Laboratory, School of Dentistry and Dental Research Institute, Seoul National University, Seoul 08826, Republic of Korea., Sinha I; Department of Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA., Shin SR; Division of Engineering in Medicine, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Cambridge, MA 02139, USA. Electronic address: sshin4@bwh.harvard.edu.

Publikováno v: Trends in biotechnology [Trends Biotechnol] 2024 Dec; Vol. 42 (12), pp. 1715-1744. Date of Electronic Publication: 2024 Sep 20.