Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Martine PUGNIERE"'
Autor:
Coraline Chéneau, Karsten Eichholz, Tuan Hiep Tran, Thi Thu Phuong Tran, Océane Paris, Corinne Henriquet, Jeffrey J. Bajramovic, Martine Pugniere, Eric J. Kremer
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Despite decades of clinical and preclinical investigations, we still poorly grasp our innate immune response to human adenoviruses (HAdVs) and their vectors. In this study, we explored the impact of lactoferrin on three HAdV types that are being used
Externí odkaz:
https://doaj.org/article/50e6d73b09c64f14b5454b2443e9f144
Autor:
Alexis Courbet, Nicole Bec, Caroline Constant, Christian Larroque, Martine Pugniere, Safia El Messaoudi, Zahraa Zghaib, Sonia Khier, Carine Deleuze-Masquefa, Florence Gattacceca
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0182022 (2017)
Displaying a strong antiproliferative activity on a wide variety of cancer cells, EAPB0203 and EAPB0503 belong to the imidazo[1,2-a]quinoxalines family of imiquimod structural analogues. EAPB0503 has been shown to inhibit tubulin polymerization. The
Externí odkaz:
https://doaj.org/article/4641e264c43e45a79d28c8192d42093a
Autor:
Karsten Eichholz, Tuan Hiep Tran, Coraline Chéneau, Thi Thu Phuong Tran, Océane Paris, Martine Pugniere, Eric J. Kremer
Publikováno v:
J Virol
Intramuscular delivery of human adenovirus (HAdV)-based vaccines leads to rapid recruitment of neutrophils, which then release antimicrobial peptides/proteins (AMPs). How these AMPs influence vaccine efficacy over the subsequent 24 h is poorly unders
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f0ea705e88ade8cfb508f0dfdc5ae6c
https://europepmc.org/articles/PMC8941863/
https://europepmc.org/articles/PMC8941863/
Autor:
Martine Pugnière, Bruno Robert, Pierre Martineau, Loïs Coënon, Jessy Présumey, Emilie Rigal, Hortense Courot, Caroline Multrier, Sara Zemiti, Jennifer Lambour, Marion de Toledo, Guillaume Bossis, Guillaume Cartron, Bénédicte Fauvel, Martin Villalba
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background Natural killer (NK) cell therapy is considered an attractive and safe strategy for anticancer therapy. Nevertheless, when autologous or allogenic NK cells are used alone, the clinical benefit has been disappointing. This is partially due t
Externí odkaz:
https://doaj.org/article/991361b1d9be41e2b17d78fb65236edd
Autor:
Stella Cesari, Yuxuan Xi, Nathalie Declerck, Véronique Chalvon, Léa Mammri, Martine Pugnière, Corinne Henriquet, Karine de Guillen, Vincent Chochois, André Padilla, Thomas Kroj
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Plant NLR proteins trigger immune responses upon recognition of pathogen effectors. Here the authors show that the integrated decoy domain of the rice NLR RGA5 can be engineered to trigger immune responses upon binding a non-cognate effector.
Externí odkaz:
https://doaj.org/article/dbf54f3a0bf34680879af90121bf1237
Autor:
Christophe Dumet, Martine Pugnière, Corinne Henriquet, Valérie Gouilleux-Gruart, Anne Poupon, Hervé Watier
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5724 (2023)
Monoclonal antibodies are biopharmaceuticals with a very long half-life due to the binding of their Fc portion to the neonatal receptor (FcRn), a pharmacokinetic property that can be further improved through engineering of the Fc portion, as demonstr
Externí odkaz:
https://doaj.org/article/0fd1142f6d854c5ca6bb1eaaf99d2da3
Autor:
Yahya Ashraf, Hanane Mansouri, Valérie Laurent-Matha, Lindsay B. Alcaraz, Pascal Roger, Séverine Guiu, Danielle Derocq, Gautier Robin, Henri-Alexandre Michaud, Helène Delpech, Marta Jarlier, Martine Pugnière, Bruno Robert, Anthony Puel, Lucie Martin, Flavie Landomiel, Thomas Bourquard, Oussama Achour, Ingrid Fruitier-Arnaudin, Alexandre Pichard, Emmanuel Deshayes, Andrei Turtoi, Anne Poupon, Joëlle Simony-Lafontaine, Florence Boissière-Michot, Nelly Pirot, Florence Bernex, William Jacot, Stanislas du Manoir, Charles Theillet, Jean-Pierre Pouget, Isabelle Navarro-Teulon, Nathalie Bonnefoy, André Pèlegrin, Thierry Chardès, Pierre Martineau, Emmanuelle Liaudet-Coopman
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-17 (2019)
Abstract Background Triple-negative breast cancer (TNBC) treatment is currently restricted to chemotherapy. Hence, tumor-specific molecular targets and/or alternative therapeutic strategies for TNBC are urgently needed. Immunotherapy is emerging as a
Externí odkaz:
https://doaj.org/article/29cfb2cf1cb546cb9c2f21a1f397c343
Autor:
Jérôme Granel, Roxane Lemoine, Eric Morello, Yann Gallais, Julie Mariot, Marion Drapeau, Astrid Musnier, Anne Poupon, Martine Pugnière, Seda Seren, Dalila Nouar, Valérie Gouilleux-Gruart, Hervé Watier, Brice Korkmaz, Cyrille Hoarau
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Granulomatosis with polyangiitis (GPA) is a severe autoimmune vasculitis associated with the presence of anti-neutrophil cytoplasmic antibodies (ANCA) mainly targeting proteinase 3 (PR3), a neutrophilic serine proteinase. PR3-ANCA binding to membrane
Externí odkaz:
https://doaj.org/article/7c2203b277ea43dd8313ce7bf3093377
Autor:
Christophe Chopard, Phuoc Bao Viet Tong, Petra Tóth, Malvina Schatz, Hocine Yezid, Solène Debaisieux, Clément Mettling, Antoine Gross, Martine Pugnière, Annie Tu, Jean-Marc Strub, Jean-Michel Mesnard, Nicolas Vitale, Bruno Beaumelle
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
It is not clear whether and how incoming HIV-1 Tat accumulates in uninfected cells. Here, Chopard et al. show that, in uninfected cells, incoming Tat is palmitoylated on Cys31 by DHHC-20, which increases its affinity for PI(4,5)P2 and results in its
Externí odkaz:
https://doaj.org/article/0b76da00f3d140a9bf12b239560dc94a
Autor:
Raquel Gutiérrez-Climente, Margaux Clavié, Jérémie Gouyon, Giang Ngo, Yoann Ladner, Pascal Etienne, Pascal Dumy, Pierre Martineau, Martine Pugnière, Catherine Perrin, Gilles Subra, Ahmad Mehdi
Publikováno v:
Molecules, Vol 26, Iss 19, p 6085 (2021)
Ordered mesoporous materials and their modification with multiple functional groups are of wide scientific interest for many applications involving interaction with biological systems and biomolecules (e.g., catalysis, separation, sensor design, nano
Externí odkaz:
https://doaj.org/article/59aa5a0128de49c5860750f711022727