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of 6
pro vyhledávání: '"Martine Lamfers"'
Autor:
Angela Costagliola di Polidoro, Giorgia Zambito, Joost Haeck, Laura Mezzanotte, Martine Lamfers, Paolo Antonio Netti, Enza Torino
Publikováno v:
Cancers, Vol 13, Iss 3, p 503 (2021)
Glioblastoma multiforme (GBM) has a mean survival of only 15 months. Tumour heterogeneity and blood-brain barrier (BBB) mainly hinder the transport of active agents, leading to late diagnosis, ineffective therapy and inaccurate follow-up. The use of
Externí odkaz:
https://doaj.org/article/ea2c1780cef044bc8df0a3bf7d6544ca
Autor:
Anne Kleijn, Jenneke Kloezeman, Elike Treffers-Westerlaken, Giulia Fulci, Sieger Leenstra, Clemens Dirven, Reno Debets, Martine Lamfers
Publikováno v:
PLoS ONE, Vol 9, Iss 5, p e97495 (2014)
The oncolytic adenovirus Delta24-RGD represents a new promising therapeutic agent for patients with a malignant glioma and is currently under investigation in clinical phase I/II trials. Earlier preclinical studies showed that Delta24-RGD is able to
Externí odkaz:
https://doaj.org/article/158d9294c950469e912b1fb756c81cee
Autor:
Archita Biswas, Manuela Salvucci, Kate Connor, Heiko Düssmann, Steven Carberry, Michael Fichtner, Ellen King, Brona Murphy, A.C O’Farrell, Jane Cryan, Alan Beausang, Josephine Heffernan, Mattia Cremona, Bryan T. Hennessy, James Clerkin, Kieron J. Sweeney, Steve MacNally, F Brett, P O’Halloran, Orna Bacon, Simon Furney, Maite Verreault, Emie Quissac, Franck Bielle, Mohammed H Ahmed, Ahmed Idbaih, Sieger Leenstra, Ioannis Ntafoulis, Federica Fabro, Martine Lamfers, Anna Golebiewska, Frank Hertel, Simone P Niclou, Romain Tching Chi Yen, Andreas Kremer, Gonca Dilcan, Francesca Lodi, Ingrid Arijs, Diether Lambrechts, Manasa Kalya P, Alexander Kel, Annette T Byrne, Jochen H.M Prehn
Publikováno v:
Journal of Neuro-Oncology.
Background Glioblastoma (GBM) is an aggressive brain cancer that typically results in death in the first 15 months after diagnosis. There have been limited advances in finding new treatments for GBM. In this study, we investigated molecular differenc
Autor:
Iris S C Verploegh, Andrea Conidi, Rutger W W Brouwer, Hayri E Balcioglu, Panagiotis Karras, Samira Makhzami, Anne Korporaal, Jean-Christophe Marine, Martine Lamfers, Wilfred F J Van IJcken, Sieger Leenstra, Danny Huylebroeck
Publikováno v:
Neuro-Oncology, 24(12), 2133-2145. Oxford University Press
Background Glioblastoma (GBM) is the most aggressive primary brain tumor. Its cellular composition is very heterogeneous, with cells exhibiting stem-cell characteristics (GSCs) that co-determine therapy resistance and tumor recurrence. Bone Morphogen
Autor:
Jacques, Grill, Birgit, Geoerger, Martine, Lamfers, Clemens, Dirven, Victor, Van Beusechem, Winald, Gerritsen, Gilles, Vassal
Publikováno v:
Bulletin du cancer. 90(12)
Cancer gene therapy has offered many hopes but its first use in humans revealed some pitfalls and at least three main problems: lack of efficacy and specificity of current vectors to deliver therapeutic genes, poor diffusion of the therapeutic effect
Autor:
Balvers RK; Corresponding Author: Martine Lamfers, PhD, Dept. of Neurosurgery, Dr. Molewaterplein 50, Ee2236, 3015GE Rotterdam, the Netherlands. m.lamfers@erasmusmc.nl., Kleijn A, Kloezeman JJ, French PJ, Kremer A, van den Bent MJ, Dirven CM, Leenstra S, Lamfers ML
Publikováno v:
Neuro-oncology [Neuro Oncol] 2013 Dec; Vol. 15 (12), pp. 1684-95. Date of Electronic Publication: 2013 Sep 17.