Zobrazeno 1 - 10
of 212
pro vyhledávání: '"Martine Jandrot Perrus"'
Autor:
Maria J. Garcia-Leon, Cristina Liboni, Vincent Mittelheisser, Louis Bochler, Gautier Follain, Clarisse Mouriaux, Ignacio Busnelli, Annabel Larnicol, Florent Colin, Marina Peralta, Naël Osmani, Valentin Gensbittel, Catherine Bourdon, Rafael Samaniego, Angélique Pichot, Nicodème Paul, Anne Molitor, Raphaël Carapito, Martine Jandrot-Perrus, Olivier Lefebvre, Pierre H. Mangin, Jacky G. Goetz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Despite abundant evidence demonstrating that platelets foster metastasis, anti-platelet agents have low therapeutic potential due to the risk of hemorrhages. In addition, whether platelets can regulate metastasis at the late stages of the di
Externí odkaz:
https://doaj.org/article/2da522b6db60448cb066c2604318bcd1
Autor:
Julien Pottecher, Francois Raffi, Martine Jandrot-Perrus, Sophie Binay, Andrea Comenducci, Violaine Desort-Henin, Déborah François, Shahin Gharakhanian, Marilyn Labart, Adeline Meilhoc, Elie Toledano, Yannick Pletan, Gilles Avenard, Victor H Sato, GARDEN Investigators
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0302897 (2024)
BackgroundGlenzocimab is a novel antithrombotic agent which targets platelet glycoprotein VI (GPVI) and does not induce haemorrhage. SARS-CoV-2 triggers a prothrombotic state and lung injury whose mechanisms include coagulopathy, endothelial dysfunct
Externí odkaz:
https://doaj.org/article/a91527e6dcb1475bae6f6ac3943ece73
Autor:
Stéphane Loyau, Anne Bauters, Nathalie Trillot, Cédric Garcia, Pierre Cougoul, Hélène Pol, Camille Paris, Geoffroy Robin, Chrystèle Rubod, Bernard Payrastre, Martine Jandrot-Perrus, Sophie Voisin, Annabelle Dupont
Publikováno v:
Platelets, Vol 34, Iss 1 (2023)
The association between endometriosis and autoimmune diseases is well known, however no acquired platelet function defect has been described so far. We describe the case of two patients with endometriosis associated with an antiplatelet glycoprotein
Externí odkaz:
https://doaj.org/article/3c671dfb1a434f2f9fcfea74a4988996
Autor:
François Delvoye, Stephane Loyau, Julien Labreuche, Guillaume Taylor, Benjamin Maier, Michel Piotin, Raphael Blanc, Simon Escalard, Lucas Di Meglio, Malek Ben Maacha, Hocine Redjem, Stanislas Smajda, Gabriele Ciccio, Solène Hébert, Candice Sabben, Martine Jandrot-Perrus, Alain Maertens De Noordhout, Mikael Mazighi, Benoit Ho-Tin-Noé, Jean-Philippe Desilles
Publikováno v:
Platelets, Vol 33, Iss 2, Pp 285-290 (2022)
Immediate reocclusion after mechanical thrombectomy (MT) for acute ischemic stroke (AIS) is a rare but devastating condition associated with poor functional outcome. The aim of this study was to gain insights into the mechanisms underlying immediate
Externí odkaz:
https://doaj.org/article/91ff75fdb90147a7a08ffcc646396594
Autor:
Stéphane Loyau Inserm, Dorothée Faille, Philippe Gautier, Paquita Nurden, Martine Jandrot-Perrus, Nadine Ajzenberg
Publikováno v:
Platelets, Vol 32, Iss 5, Pp 705-709 (2021)
Acquired deficiencies in platelet glycoprotein VI are rare and have not been found associated with other defects. Here we report the case of a 64-year old male patient presenting an immune GPVI deficiency associated to a mutation in the alpha-actinin
Externí odkaz:
https://doaj.org/article/2cbf19bd53bb46b98c10c5dbbc6f919f
Autor:
Hari Hara Sudhan Lakshmanan, Alexander R. Melrose, Anna-Liisa I. Sepp, Annachiara Mitrugno, Anh T. P. Ngo, Ayesha Khader, Rachel Thompson, Daniel Sallee, Jiaqing Pang, Pierre H. Mangin, Martine Jandrot-Perrus, Joseph E. Aslan, Owen J.T. McCarty
Publikováno v:
Platelets, Vol 32, Iss 3, Pp 424-428 (2021)
The core structure of the extracellular basement membrane is made up of self-assembling networks of collagen and laminin which associate with each other through the bridging adapter proteins including the sulfated monomeric glycoprotein nidogen. Whil
Externí odkaz:
https://doaj.org/article/16f3f750d1f24147a66dcc9bae405302
Autor:
Ilaria De Simone, Constance C. F. M. J. Baaten, Martine Jandrot-Perrus, Jonathan M. Gibbins, Hugo ten Cate, Johan W. M. Heemskerk, Chris I. Jones, Paola E. J. van der Meijden
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 18, p 10203 (2022)
Platelet and coagulation activation are highly reciprocal processes driven by multi-molecular interactions. Activated platelets secrete several coagulation factors and expose phosphatidylserine, which supports the activation of coagulation factor pro
Externí odkaz:
https://doaj.org/article/c894090488b14fa089e8e28a38da2d55
Autor:
Muhammad Usman Ahmed, Nicolas Receveur, Emily Janus‐Bell, Clarisse Mouriaux, Christian Gachet, Martine Jandrot‐Perrus, Béatrice Hechler, Elizabeth E. Gardiner, Pierre H. Mangin
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 5, Iss 5, Pp n/a-n/a (2021)
Abstract Background The interplay between platelets and fibrinogen is the cornerstone of thrombus formation. Integrin αIIbβ3 is the main platelet adhesion receptor for fibrinogen and mediates an outside‐in signal upon ligand binding that reinforc
Externí odkaz:
https://doaj.org/article/79f281201ef34fe6b728f32d8e5e66e2
Publikováno v:
Platelets, Vol 30, Iss 6, Pp 708-713 (2019)
Platelet membrane glycoprotein VI (GPVI) is increasingly recognized as an important receptor for thrombus formation and growth. Numerous arguments have been published indicating that GPVI plays a major role in thrombosis without being essential for p
Externí odkaz:
https://doaj.org/article/025fa129574f4e269e1a85ff4f209f04
Autor:
Cécilia Delattre, Diego Velazquez, Caroline Roques, Graciela Pavon-Djavid, Véronique Ollivier, Anna Lokajczyk, Thierry Avramoglou, Virginie Gueguen, Liliane Louedec, Giuseppina Caligiuri, Martine Jandrot-Perrus, Catherine Boisson-Vidal, Didier Letourneur, Anne Meddahi-Pelle
Publikováno v:
BioImpacts, Vol 9, Iss 1, Pp 25-36 (2019)
Introduction: The major complications of stent implantation are restenosis and late stent thrombosis. PBMA polymers are used for stent coating because of their mechanical properties. We previously synthesized and characterized Dextrangraft-polybutylm
Externí odkaz:
https://doaj.org/article/bbdfbc36412f47048a2b222bdcc62bb1