Zobrazeno 1 - 10
of 330
pro vyhledávání: '"Martine J Jager"'
Autor:
Alina Miron, Sorcha Ní Dhubhghaill, Viridiana Kocaba, Martine J Jager, Gerrit R J Melles, Silke Oellerich
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285609 (2023)
In this study we describe peripheral corneal endothelial cell migration in vitro in the absence and presence of a ROCK-inhibitor. For this study, 21 corneal endothelial graft rims, with attached trabecular meshwork (TM), were prepared from Descemet m
Externí odkaz:
https://doaj.org/article/a7aad3a405dd430fa887f5605307aa80
Autor:
T Huibertus van Essen, Sake I van Pelt, Inge H G Bronkhorst, Mieke Versluis, Fariba Némati, Cécile Laurent, Gregorius P M Luyten, Thorbald van Hall, Peter J van den Elsen, Pieter A van der Velden, Didier Decaudin, Martine J Jager
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164292 (2016)
Uveal melanoma (UM) with an inflammatory phenotype, characterized by infiltrating leukocytes and increased human leukocyte antigen (HLA) expression, carry an increased risk of death due to metastases. These tumors should be ideal for T-cell based the
Externí odkaz:
https://doaj.org/article/81eba8a66d0847c4b825c012cde07949
Autor:
Mark J de Lange, Lubna Razzaq, Mieke Versluis, Sven Verlinde, Mehmet Dogrusöz, Stefan Böhringer, Marina Marinkovic, Gregorius P M Luyten, Rob J W de Keizer, Frank R de Gruijl, Martine J Jager, Pieter A van der Velden
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138002 (2015)
Uveal melanomas (UM) originate from melanocytes in the interior wall of the eye, namely from the iris, ciliary body and the choroid with marked differences in light exposure (from dark anterior to illuminated posterior). In contrast to UV radiation,
Externí odkaz:
https://doaj.org/article/cde04f31e7364c04b9174b39f6f9d888
Autor:
Mieke Versluis, Mark J de Lange, Sake I van Pelt, Claudia A L Ruivenkamp, Wilma G M Kroes, Jinfeng Cao, Martine J Jager, Gre P M Luyten, Pieter A van der Velden
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0116371 (2015)
Uveal melanoma (UM) development and progression is correlated with specific molecular changes. Recurrent mutations in GNAQ and GNA11 initiate UM development while tumour progression is correlated with monosomy of chromosome 3 and gain of chromosome 8
Externí odkaz:
https://doaj.org/article/6d302590983641da984258cff1c9598d
Autor:
Rosaria Gangemi, Valentina Mirisola, Gaia Barisione, Marina Fabbi, Antonella Brizzolara, Francesco Lanza, Carlo Mosci, Sandra Salvi, Marina Gualco, Mauro Truini, Giovanna Angelini, Simona Boccardo, Michele Cilli, Irma Airoldi, Paola Queirolo, Martine J Jager, Antonio Daga, Ulrich Pfeffer, Silvano Ferrini
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29989 (2012)
Uveal melanoma is an aggressive cancer that metastasizes to the liver in about half of the patients, with a high lethality rate. Identification of patients at high risk of metastases may provide indication for a frequent follow-up for early detection
Externí odkaz:
https://doaj.org/article/8794d72c7aff40deaffe0b6d143e0664
Autor:
Martine J Jager
Publikováno v:
Journal of Ophthalmic & Vision Research, Vol 9, Iss 1, Pp 1-2 (2014)
Externí odkaz:
https://doaj.org/article/01f4e33f05b14c03bf497c7012cfed38
Autor:
Ruben V. Huis in ‘t Veld, Pablo Lara, Martine J. Jager, Roman I. Koning, Ferry Ossendorp, Luis J. Cruz
Publikováno v:
Journal of Nanobiotechnology, Vol 20, Iss 1, Pp 1-18 (2022)
Abstract Extracellular vesicles (EVs) are promising drug carriers of photosensitizers for photodynamic therapy (PDT) in cancer treatment, due to their ability to circulate in blood and enter cells efficiently. The therapeutic potential of EVs has bee
Externí odkaz:
https://doaj.org/article/d1583bc64cce4b1b8b12030c820a96bc
Autor:
Richard D. Carvajal, Joseph J. Sacco, Martine J. Jager, David J. Eschelman, Roger Olofsson Bagge, J. William Harbour, Nicholas D. Chieng, Sapna P. Patel, Anthony M. Joshua, Sophie Piperno-Neumann
Publikováno v:
Nature Reviews Clinical Oncology. 20:99-115
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d44db20830e92ce55d7c829368d5b85c
https://doi.org/10.1038/s41571-022-00714-1
https://doi.org/10.1038/s41571-022-00714-1
Autor:
Ruben Victor Huis in ‘t Veld, Candido G. Da Silva, Martine J. Jager, Luis J. Cruz, Ferry Ossendorp
Publikováno v:
Pharmaceutics, Vol 13, Iss 9, p 1470 (2021)
Photodynamic therapy (PDT) has shown encouraging but limited clinical efficacy when used as a standalone treatment against solid tumors. Conversely, a limitation for immunotherapeutic efficacy is related to the immunosuppressive state observed in lar
Externí odkaz:
https://doaj.org/article/45c2b9340675421d8caa7b12205d53b1
Autor:
Maria Chiara Gelmi, Robert M. Verdijk, Laurien E. Houtzagers, Pieter A. van der Velden, Wilma G. M. Kroes, Gregorius P. M. Luyten, T. H. Khanh Vu, Martine J. Jager
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 10; Pages: 8861
International Journal of Molecular Sciences, 24(10):8861. Multidisciplinary Digital Publishing Institute (MDPI)
International Journal of Molecular Sciences, 24(10):8861. Multidisciplinary Digital Publishing Institute (MDPI)
Microphthalmia-associated transcription factor (MITF) is an important regulator of melanogenesis and melanocyte development. In cutaneous melanoma, MITF loss has been linked to an increased expression of stem cell markers, a shift in epithelial-to-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ab5c0d094b8a345aca2f5b66571cd47